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Einstein (São Paulo)

Print version ISSN 1679-4508On-line version ISSN 2317-6385

Abstract

VIANA, Ana Carolina Cavalcante et al. Correlation between nutritional assessment and oxidative stress in candidates for liver transplant. Einstein (São Paulo) [online]. 2020, vol.18, eAO4039.  Epub Dec 13, 2019. ISSN 1679-4508.  https://doi.org/10.31744/einstein_journal/2020ao4039.

Objective

To evaluate the oxidative profile, nutritional status and food intake (caloric value; macronutrients; vitamins A, E and C; and zinc), and to correlate oxidative stress with nutritional status in patients who were candidates for liver transplant.

Methods

This is a cross-sectional, analytical, and descriptive study with 51 candidates for liver transplant. Sociodemographic and clinical data, anthropometric parameters, food consumption, and a 10mL blood sample were collected from each patient. Oxidative stress was analyzed by the thiobarbituric acid method. The consumption of macronutrients, caloric value and micronutrients (zinc, vitamins A, E and C) were qualitatively analyzed, and zinc was also quantitatively analyzed.

Results

The mean age was 49.17±8.17 years. The highest percentage of malnutrition was according to arm muscle circumference (56.86%), followed by arm circumference (52.94%), triceps skin fold (50.98%), and body mass index (1.96%). The mean malondialdehyde level was 14.80±8.72μM/L, presenting a negative correlation with the body mass index for patients with liver cirrhosis according to IMC-Campillo values (p=0.001; r=-0.430). Low energy, carbohydrate, protein, vitamin A and E consumption were observed in more than 50% of subjects.

Conclusion

This study showed an association of nutritional status through body mass index for patients with liver cirrhosis according to IMC-Campillo, with oxidative stress in patients with liver cirrhosis on a liver transplant waiting list.

Keywords : Nutrition assessment; Oxidative stress; Antioxidants; Eating; Liver cirrhosis.

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