ABSTRACT
BACKGROUND AND OBJECTIVES:
This study aimed at evaluating postoperative analgesia with ropivacaine instillation inside the peritoneal cavity in videolaparoscopic cholecystectomy.
METHODS:
This is a randomized clinical trial with 60 patients. The intervention group (RP, n = 30) received 0.5% ropivacaine instillation in right and left subdiaphragmatic regions and in gallbladder bed in equal volumes of 10 mL. The control group (SS, n = 30) received 0.9% saline solution instillation. Patients of both groups received multimodal analgesia. Scores of abdominal pain and referred pain in shoulder were evaluated at emergence and after 1, 2, 4, 12 and 24 hours, in addition to the need for rescue analgesia, opioid consumption and adverse events, considering statistically significant p<0.05.
RESULTS:
There has been no statistical difference between groups with regard to demographic data and anesthetic-surgical time. The intervention group had lower and statistically significant pain scores as compared to control group at emergence (p=0.001), 1 (p=0.019) and 2 (p=0.04) postoperative hours, in addition to lower opioid consumption at emergence (p=0.022) and in total in the first 24 hours (p=0.001). Time for first request for rescue analgesia was longer in the intervention group (p=0.001).
CONCLUSION:
Ropivacaine instillation inside the peritoneal cavity has decreased pain scores in the first 2 hours and postoperative opioid consumption.
Keywords:
Analgesia; Laparoscopic cholecystectomy; Local anesthetics; Postoperative pain; Ropivacaine