Borges 2007 Brazil |
Cross-sectional |
318 |
57 |
46.2 |
64.3 |
Partial |
NCEP ATP III |
MS |
Association between PD and MS OR 1.11 (0.67-1.83) |
Shimazaki 2007 Japan |
Cross-sectional |
584 |
55.7 |
zero |
6.7% |
Partial |
NCEP ATP III |
PD |
Women with mean PPD ≥ 2mm: OR 4.7 (2.4- 9.7) Women with mean CAL≥ 3mm: 3.3 (1.2- 8.8) |
D'Aiuto 2008 USA |
Cross-sectional |
13,677 |
40.7 |
62.0 |
30.6 |
Partial |
IDF 2005 |
MS |
Association between PD and MS: Moderate PD: OR 1.07 (0.84-1.36) Patients aged >44 years OR 1.06 (0.83-1.34); for non-smokers OR 0.91 (0.56-1.48) Severe PD: OR 1.45 (0.91-2.33) Patients aged >44 years OR 1.74 (1.10-1.76); for non-smokers OR 2.31 (1.13-1.73) |
Khader 2008 Jordan |
Cross-sectional |
156 |
47.2 |
35.9 |
41.0 |
Complete |
NCEP ATP III |
PD |
Association between MS and PD: PPD and CAL were 2.2mm and 0.9m, respectively, greater in Individuals with MS as opposed to those without the condition. |
Kowalski 2009 Poland |
Cross-sectional |
380 |
42.0 |
67.9 |
Not determined |
Partial |
IDF 2005 |
MS |
Direct association between MS and PD was not described. |
Kushiyama 2009 Japan |
Cross-sectional |
1,070 |
63.3 |
26.7 |
9.2 |
Complete |
NCEP ATPIII |
PD |
Association between MS and PD: OR 2.13 (1.22-3.70) |
Li 2009 China |
Case-control |
208 |
60.9 |
56.7 |
20.2 |
Complete |
IDF 2005 |
MS |
Association between MS and PD: OR for % CAL ≥3 and MS tertiles: 0-33 OR 6.91 (1.07-44.77) 33-67 OR 9.89 (1.50-65.24) 67-100 OR 15.60 (2.20-110.43) |
Morita 2009 Japan |
Cross-sectional |
2,478 |
43.3 |
81.8 |
32.1 |
Partial |
Modified (Japanese) IDF 2005
|
MS |
Association between MS and PD: OR of 2.40 (1.70-2.70) |
Andriankaja 2010 USA |
Cross-sectional |
7,431 |
40.45 |
47.32 |
26.77 |
Partial |
NCPEP-ATPIII |
PD |
Association between MS and PD: OR 2.10 (1.20 −3.70) In men, OR 1.00 (0.60 −1.70) In women OR 4.70 (2.00 −11.20). |
Benguigui 2010 France |
Cross-sectional |
255 |
57.9 |
54.9 |
19.2 |
Complete |
NCEP ATPIII |
PD |
Association between MS and PD: Moderate: OR 1.54 (0.59-4.01) Severe: OR 1.97 (0.74-5.23) |
Han 2010 South Korea |
Cross-sectional |
1,046 |
42.3 |
43.7 |
26.5 |
Partial |
AHA/NHBLI and IDF 2009 |
PD |
Association between MS and PD: OR 1.70 (1.22-2.37) |
Morita 2010 Japan |
Retrospective Cohort |
1,023 |
37.1 |
71.0 |
31.3 |
Partial |
Modified (Japanese) IDF 2005 ** |
MS |
Association between PD and MS: OR 1.60 (1.10- 2.20); individuals with PD presented with at least one symptom of MS after 4 years of follow-up. |
Timonen 2010 Finland |
Cross-sectional |
2,050 |
46.0 |
39.2 |
Zero |
Complete |
WHO |
PD |
Association between MS and PD: RR of 1.19 (1.01- 1.42) for PPD ≥ 4 RR of 1.5 (0.96- 2.36) for PPD ≥ 6 |
Bracho 2011 Venezuela |
Cross-sectional |
292 |
48.3 % 30-49 years old |
42.4 |
Not reported |
Partial |
AHA/NHBLI and IDF 2009 |
MS |
Descriptive analysis, association not reported. |
Chen 2011 Taiwan |
Cross-sectional |
253 |
58.8 |
46.2 |
29.6 |
Partial |
NCEP ATP III |
MS |
Association between PD and MS: OR 2.73 (1.29-5.79) |
Li 2011 China |
Cross-sectional |
59 |
57.8 |
42.4 |
6.8 |
Complete |
IDF 2005 |
atherosclerosis |
Primary outcome was atherosclerosis; direct association between MS and PD was not described. |
Kwon 2011 Korea |
Cross-sectional |
7,178 |
45.6 |
37.5 |
37.0 |
Partial |
NCEP ATP III |
PD |
Association between PD and MS: OR 1.55 (1.32-1.83) |
Fukui 2012 Japan |
Cross-sectional |
6,421 |
43.4 |
76.9 |
25.1 |
Partial |
NCEP ATP III |
MS |
Association between PD and MS: Moderate OR 1.25 (1.05-1.49) Severe OR 1.32 (1.01-1.71) |
Yu 2012 China |
Cross-sectional |
903 |
62.6 |
50.5 |
20.2 |
Complete |
IDF 2005 |
PD |
Association between PD severity and MS: OR 1.524 (1.066-2.328) |
Sora 2013 USA |
Cross-sectional |
283 |
55.3 |
24.0 |
42.0 |
Complete |
NCEP ATP III |
PD |
Association between MS and PD: Sites with PPD ≥5mm: RR 2.18 (0.98 – 4.87) Sites with CAL ≥ 6mm : RR 2.77 (1.11 – 6.93) |
Furuta 2013 Japan |
Cross-sectional |
2,370 |
59.5 |
43.9 |
Not described |
Complete |
NCEP ATP III |
PD |
MS and PPD >3.0mm Women: OR 3.06 (1.42-6.59) Men: OR 1.32 (0.75–2.34) MS and PPD >3.5mm Women: OR 3.60 (1.30–12.61) Men: OR 1.21 (0.59–2.49) |
Thanakun 2014 Taiwan |
Cross-sectional |
125 |
47 |
42.4 |
8.8 |
Complete |
AHA/NHBLI and IDF 2009 |
PD |
Association between MS and PD: CAL>4mm: OR 3.60 (1.34-9.65) PPD> 4mm+ BOP> 10% sites: OR 6.94 (1.62-29.80) |
LaMonte 2014 USA |
Cross-sectional |
653 |
65.5 |
zero |
2.1 |
Complete |
NCEP ATP III |
MS |
MS was associated with supragingival plaque OR 1.47 (1.00-2.16) MS and PD (criteria 1) Severe: OR 1.02 (0.62, 1.68) MS and PD (criteria 2) Severe: OR 1.11 (0.71, 1.75) |
Alhabashneh 2015 Jordan |
Cross-sectional |
280 |
53.8 |
50.7 |
21.8 |
Complete |
IDF 2005 |
PD |
Association between MS and PD: OR 3.28 (1.30-8.30) |
Gomes-Filho 2015 Brazil |
Cross-sectional |
419 |
59 |
38.2 |
29.8 |
Complete |
IDF 2005 |
MS |
Association between PD and MS: Diagnosis of periodontitis: 0.98 (0.62 – 1.53) Severe periodontitis: 2.11 (1.01 – 4.40) |
Kim 2015 Korea |
Cross-sectional |
6,620 |
60.7 63.0 |
47.4 |
16.6 |
Partial |
AHA/NHBLI |
PD |
Descriptive analysis, association not reported. |
Minagawa 2015 Japan |
Cross-sectional |
234 |
80 |
47.4 |
5.5 |
Complete |
Modified (Japanese) IDF 2005
|
PD |
Association between MS and severity of PD: OR 2.10 (1.03-4.28) |
Safavi 2015 Iran |
Cross-sectional |
834 |
15-75 |
Not described |
Not described |
Partial |
NCEP ATP III |
PD |
Association between PD and MS: OR 1.58 (1.1-2.2) |
Chen 2016 China |
Cross-sectional |
303 |
34.9 |
100 |
31 |
Partial |
IDF 2009 |
MS |
Descriptive analysis, association not reported. |
Jaramillo 2016 Colombia |
Case-control |
651 |
27-84 |
36.1 |
20.1 |
Complete |
AACE 2003 |
PD |
Association between PD and MS: OR 2.72 (1.09–6.79) |
Kaye 2016 USA |
Cohort |
760 |
61 |
100 |
3.0 |
Complete |
IDF 2009 NCEP ATP III |
MS |
Association between MS and PD: PPD ≥5 mm: OR 1.37 (1.14 to 1.65) CAL ≥5 mm: OR 1.19 (1.00 to 1.41) |
Musskopf 2016 Brazil |
Cross-sectional |
363 |
18-81 |
36.1 |
44.1 |
Complete |
IDF 2009 |
MS |
Association between MS and Severe PD: PR 1.62 (1.13–2.34) |
Kikui 2017 Japan |
Cross-sectional |
1,856 |
66.4 |
41.6 |
9.8 |
Partial |
AHA/NHBLI and IDF 2009 |
PD |
Association between PD and MS components: Three components: OR 1.42 (1.03-1.96) Four components: OR 1.89 (1.31-2.73) |