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Motor impairments and predictors of mobility loss at the end of hospitalization in individuals with neurotoxoplasmosis

ABSTRACT

Neurotoxoplasmosis (NTX) is one of the main opportunistic diseases present in individuals with the human immunodeficiency virus (HIV). This disease promotes focal brain lesions with mass effect that can generate a variety of sequelae capable of compromising the performance of activities of daily living, including ambulation. Our study sought to verify the main motor deficits presented and identify risk factors for mobility loss at the end of hospitalization. It is a observational study, whose sample consisted of data from medical records of individuals with HIV and diagnosed with NTX. Electronic medical records were reviewed, clinical and epidemiological data were collected and hospital mobility was classified. Descriptive statistics and binary logistic regression were applied. We evaluated 161 medical records, with male prevalence, with a median age of 39 years. Motor deficits at admission were absence of ambulation (42.9%), hemiparesis (42.3%), lower limb paresis (37.3%), balance deficit (35.4%) and 32.9 % could not walk at the end of hospitalization. Predictors of mobility loss at the end of hospitalization were: use of invasive mechanical ventilation (IMV), inclusion in the palliative care program and non-ambulation on admission. The main motor deficits were the absence of ambulation, hemiparesis on the right and the balance deficit. The predictors for inability to walk at the end of hospitalization were the need for IMV, inclusion in the palliative care program, and no ambulation at admission.

Keywords|
Toxoplasmosis, Cerebral; HIV; Motor Disorders

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