SciELO - Scientific Electronic Library Online

vol.23 issue3Assessment of changes in spine curvatures and the sensations caused in three different types of working seatsDifferences in game statistics between winning and losing for male wheelchair tennis players in Paralympics Games author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Motriz: Revista de Educação Física

On-line version ISSN 1980-6574


FEITOZA, Maiane da Silva et al. Effect of salbutamol on the cardiovascular response in healthy subjects at rest, during physical exercise, and in recovery phase: a randomized, double-blind, crossover study. Motriz: rev. educ. fis. [online]. 2017, vol.23, n.3, e101737.  Epub Nov 13, 2017. ISSN 1980-6574.


To evaluate the effect of the short-acting beta agonists (SABAs) salbutamol on cardiovascular response rest, exercise and recovery phase.


This study was conducted as a randomized, double-blind, placebo controlled, crossover study in 15 healthy adults, with a mean age of 30.2±6.6 years. Participants underwent a maximal effort test on two non-consecutive days with 400 mcg of salbutamol or placebo. Throughout the protocol, the variables HR, blood pressure (BP), perceived rate of effort (modified Borg scale) and peak expiratory flow (PEF) were monitored.


After salbutamol, baseline HR and PEF had increase from 71±8 to 80±11 bpm (p<0.05) and 454.0±64.5 to 475.3±71.4 L/min (p < 0.05), respectively. The variables HR, BP and Borg were similar between interventions during all the protocol phases (p>0.05).


Administration of salbutamol increased rest heart rate; however, did not change heart rate, blood pressure and perceived exertion during exercise or recovery. This suggests that the salbutamol administration is safe and does not affect exercise intensity prescription in healthy subjects.

Keywords : salbutamol; exercise; eeart rate; blood pressure; healthy subject.

        · text in English     · English ( pdf )