Monogenea
|
Pseudodactylogyrus sp. |
Anguilla anguilla
|
Acquired resistance (Unknown mechanism); |
Slotved & Buchmann (1993)Slotved HC, Buchmann K. Acquired resistance of the eel, Anguilla anguilla L., to challenge infections with gill monogeneans. J Fish Dis 1993; 16(6): 585-591. http://dx.doi.org/10.1111/j.1365-2761.1993.tb00895.x. http://dx.doi.org/10.1111/j.1365-2761.19...
|
Neobenedenia girellae
|
Paralichtys olivaceus
|
Acquired resistance (Unknown mechanism); |
Bondad-Reantaso et al. (1995)Bondad-Reantaso MG, Ogawa K, Yoshinaga T, Wakabayashi H. Acquired protection against Neobenedenia girellae in Japanese flounder. Fish Pathol 1995; 30(3): 233-238. http://dx.doi.org/10.3147/jsfp.30.233. http://dx.doi.org/10.3147/jsfp.30.233...
|
Neobenedenia girellae
|
Paralichtys olivaceus
|
Increased IgM level |
Wang et al (1997)Wang G, Kim JH, Sameshima M, Ogawa K. Detection of antibodies against the monogenean Heterobothrium okamotoi in tiger puffer by ELISA. Fish Pathol 1997; 32(3): 179-180. http://dx.doi.org/10.3147/jsfp.32.179. http://dx.doi.org/10.3147/jsfp.32.179...
|
Gyrodactylus derjavini
|
Oncorhynchus mykiss
|
Alternative complement pathway activation; |
Buchmann (1998)Buchmann K. Binding and lethal effect of complement from Oncorhynchus mykiss on Gyrodactylus derjavini (Platyhelminthes: monogenea). Dis Aquat Organ 1998; 32(3): 195-200. http://dx.doi.org/10.3354/dao032195. PMid:9676245. http://dx.doi.org/10.3354/dao032195...
|
Gyrodactylus salaris
|
Salmo salar
|
Alternative complement pathway activation: factors in host serum and mucus; |
Harris et al. (1998)Harris PD, Soleng A, Bakke TA. Killing of Gyrodactylus salaris (Platyhelminthes, Monogenea) mediated by host complement. Parasitology 1998; 117(Pt2): 137-143. http://dx.doi.org/10.1017/S003118209800287X. PMid:9778636. http://dx.doi.org/10.1017/S0031182098002...
|
Pseudodactylogyrus anguillae
|
Anguilla anguilla
|
Antibody production; |
Mazzanti et al. (1999)Mazzanti C, Monni G, Cognetti V. Observations on antigenic activity of Pseudodactylogyrus anguillae (Monogenea) on the European eel (Anguilla anguilla). Bull Eur Assoc Fish Pathol 1999; 19(2): 57-59.
|
Neoheterobothrium hirame
|
Paralichthys olivaceus
|
Increased expression of genes related to proteases, immunoglobulin light chain, immunoglobulin heavy chain and B cell differentiation; |
Matsuyama et al. (2007)Matsuyama T, Fujiwara A, Nakayasu C, Kamaishi T, Oseko N, Tsutsumi N, et al. Microarray analyses of gene expression in Japanese flounder Paralichthys olivaceus leucocytes during monogenean parasite Neoheterobothrium hirame infection. Dis Aquat Organ 2007; 75(1): 79-83. http://dx.doi.org/10.3354/dao075079. PMid:17523546. http://dx.doi.org/10.3354/dao075079...
|
Neobenedenia melleni
|
Oreochromis mossambicus
|
Specific antibody production detected in host serum and mucus; |
Kishimori et al. (2015)Kishimori JM, Takemura A, Leong JAC. Neobenedenia melleni-specific antibodies are associated with protection after continuous exposure in Mozambique Tilapia. J Immunol Res 2015; 2015: 635387. http://dx.doi.org/10.1155/2015/635387. PMid:25756055. http://dx.doi.org/10.1155/2015/635387...
|
Neobenedenia melleni
|
Seriola lalandi
|
Increased level of total protein concentration in serum and anti-protease and myeloperoxidase activity; |
Reyes-Becerril et al. (2017)Reyes-Becerril M, Alamillo E, Trasviña A, Hirono I, Kondo H, Jirapongpairoj W, et al. In vivo and in vitro studies using larval and adult antigens from Neobenedenia melleni on immune response in yellowtail (Seriola lalandi). J Fish Dis 2017; 40(11): 1497-1509. http://dx.doi.org/10.1111/jfd.12620. PMid:28422295. http://dx.doi.org/10.1111/jfd.12620...
|
Gyrodactylus kobayashii
|
Carassius auratus
|
Increased expression of inflammatory genes: IL-1β2, TNF-α1 and TNF-α2; |
Zhou et al. (2018)Zhou S, Li WX, Zou H, Zhang J, Wu SG, Li M, et al. Expression analysis of immune genes in goldfish (Carassius auratus) infected with the monogenean parasite Gyrodactylus kobayashii. Fish Shellfish Immunol 2018; 77: 40-45. http://dx.doi.org/10.1016/j.fsi.2018.03.033. PMid:29567133. http://dx.doi.org/10.1016/j.fsi.2018.03....
|
Thaparocleidus sp.
|
Pangasianodon hypophthalmus
|
Increased production of lactate dehydrogenase, lactate, creatinine, serum glutamate-oxaloacetate transaminase and serum glutamate-pyruvate transaminase; |
Kumar et al. (2018)Kumar S, Raman RP, Prasad KP, Srivastava PP, Kumar S, Rajendran KV. Effects on haematological and serum biochemical parameters of Pangasianodon hypophthalmus to an experimental infection of Thaparocleidus sp. (Monogenea: dactylogyridae). Exp Parasitol 2018; 188: 1-7. http://dx.doi.org/10.1016/j.exppara.2018.02.007. PMid:29501694. http://dx.doi.org/10.1016/j.exppara.2018...
|
(b)
|
Parasite |
Species |
Host |
Immune response |
Reference |
Cestoda
|
Diphyllobothrium spp. |
Salmo gairdneri
|
Antibody production correlated with worm burdens in individual fish; |
Sharp et al (1989)Sharp GJE, Pike AW, Secombes CJ. The immune response of wild rainbow trout, Salmo gairdneri Richardson, to naturally acquired plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824) and D. ditremum (Creplin, 1825). J Fish Biol 1989; 35(6): 781-794. http://dx.doi.org/10.1111/j.1095-8649.1989.tb03029.x. http://dx.doi.org/10.1111/j.1095-8649.19...
|
Diphyllobothrium dendriticum
|
Oncorhynchus mykiss
|
Antibody production after 5 weeks of experimental infection; |
Sharp et al. (1992)Sharp GJE, Pike AW, Secombes CJ. Sequential development of the immune response in rainbow trout [Oncorhynchus mykiss (Walbaum, 1792)] to experimental plerocercoid infections of Diphyllobothrium dendriticum (Nitzsch, 1824). Parasitology 1992; 104(1): 169-178. http://dx.doi.org/10.1017/S0031182000060911. PMid:1614733. http://dx.doi.org/10.1017/S0031182000060...
|
Ligula intestinalis
|
Rutilus rutilus
|
Specific antibody production to tegumental antigens; |
Williams & Hoole (1992)Williams MA, Hoole D. Antibody response of the fish Rutilus rutilus to the metacestode of Ligula intesinalis. Dis Aquat Organ 1992; 12: 83-89. http://dx.doi.org/10.3354/dao012083. http://dx.doi.org/10.3354/dao012083...
|
Diphyllobothrium dendriticum
|
Coregonus migratorius
|
Suppression of antibody production; |
Mazur & Tolochko (2015)Mazur OE, Tolochko LV. Cytomorphological and biochemical characteristics of the whitefish, Baikal omul Coregonus migratorius, infected by plerocercoids of Diphyllobothrium dendriticum (Cestoda: pseudophyllidae). Biol Bull 2015; 42(2): 117-123. http://dx.doi.org/10.1134/S1062359015020065. PMid:26021157. http://dx.doi.org/10.1134/S1062359015020...
|
(c)
|
Parasite |
Species |
Host |
Immune response |
Reference |
Trematoda
|
Telogaster opisthorchis
|
Anguilla australis schmidtii;
Anguilla dieffenbachii
|
Antibody production detected in plasm and intestinal mucus. |
McArthur (1978)McArthur CP. Humoral antibody production by New Zealand eels, against the intestinal trematode Telogaster opisthorchis Macfarlane, 1945. J Fish Dis 1978; 1(4): 377-387. http://dx.doi.org/10.1111/j.1365-2761.1978.tb00042.x. http://dx.doi.org/10.1111/j.1365-2761.19...
|
Diplostomum spathaceum
|
Salmo gairdneri
|
Acquired resistance (Unknown mechanism). |
Stables & Chappell (1986)Stables JN, Chappell LH. Putative immune response of rainbow trout, Salmo gairdneri, to Diplostomum spathaceum infections. J Fish Biol 1986; 29(1): 115-122. http://dx.doi.org/10.1111/j.1095-8649.1986.tb04931.x. http://dx.doi.org/10.1111/j.1095-8649.19...
|
Diplostomum spathaceum
|
Oncorhynchus mykiss
|
Acquired resistance (increased level of total immunoglobulins and in the proportion of neutrophils and monocytes); |
Höglund & Thuvander (1990)Höglund J, Thuvander A. Indications of non-specific protective mechanisms in rainbow trout Oncorhynchus mykiss with diplostomosis. Dis Aquat Organ 1990; 8(2): 91-97. http://dx.doi.org/10.3354/dao008091. http://dx.doi.org/10.3354/dao008091...
|
Rhipidocotyle fennica
|
Rutilus rutilus
|
Acquired resistance (increased IgM production); |
Aaltonen et al. (1997)Aaltonen TM, Valtonen ET, Jokinen EI. Humoral response of roach (Rutilus rutilus) to digenean Rhipidocotyle fennica infection. Parasitology 1997; 114(3): 285-291. http://dx.doi.org/10.1017/S0031182096008499. http://dx.doi.org/10.1017/S0031182096008...
|
Diplostomum spathaceum
|
Oncorhynchus mykiss
|
Acquired resistance (Unknown mechanism). |
Karvonen et al. (2004)Karvonen A, Hudson PJ, Seppälä O, Valtonen ET. Transmission dynamics of a trematode parasite: exposure, acquired resistance and parasite aggregation. Parasitol Res 2004; 92(3): 183-188. http://dx.doi.org/10.1007/s00436-003-1035-y. PMid:14652746. http://dx.doi.org/10.1007/s00436-003-103...
|
Cardicola forsteri
|
Thunnus maccoyii
|
Acquired resistance (antibody production); |
Aiken et al. (2008)Aiken HM, Hayward CJ, Crosbie P, Watts M, Nowak BF. Serological evidence of an antibody response in farmed southern bluefin tuna naturally infected with the blood fluke Cardicola forsteri. Fish Shellfish Immunol 2008; 25(1-2): 66-75. http://dx.doi.org/10.1016/j.fsi.2007.12.010. PMid:18502150. http://dx.doi.org/10.1016/j.fsi.2007.12....
|
Cardicola oriental; Cardicola opisthorchis
|
Thunnus orientalis
|
Increased transcription of IgM, MHC2, TCR-β and IL-8 in heart; Only IgM increased transcription in gills; |
Polinski et al. (2014)Polinski M, Shirakashi S, Bridle A, Nowak B. Transcriptional immune response of cage-cultured Pacific bluefin tuna during infection by two Cardicola blood fluke species. Fish Shellfish Immunol 2014; 36(1): 61-67. http://dx.doi.org/10.1016/j.fsi.2013.10.008. PMid:24161760. http://dx.doi.org/10.1016/j.fsi.2013.10....
|
(d)
|
Parasite |
Species |
Host |
Immune response |
Reference |
Nematoda
|
Anguillicola crassus
|
Anguilla anguilla
|
Specific antibody production |
Buchmann et al. (1991)Buchmann K, Pedersen LØ, Glamann J. Humoral immune response of European eel Anguilla anguilla to a major antigen in Anguillicola crassus (Nematoda). Dis Aquat Organ 1991; 12(1): 55-57.
|
Anisakis simplex
|
Pollachius virens
|
Acquired resistance (antibody production); |
Priebe et al. (1991)Priebe K, Huber C, Märtlbauer E, Terplan G. Detection of antibodies against the larva of Anisakis simplex in the pollock Pollachius virens using ELISA. Zentralbl Veterinärmed B 1991; 38(3): 209-214. PMid:1858459.
|
Anguillicola crassus
|
Anguilla anguilla
|
Specific antibody production in response to natural infection and injected whole-worm extract; |
Höglund & Pilström (1994)Höglund J, Pilström L. Purification of adult Anguillicola crassus whole-worm extract antigens for detection of specific antibodies in serum from the European eel (Anguilla anguilla) by ELISA. Fish Shellfish Immunol 1994; 4(4): 311-319. http://dx.doi.org/10.1006/fsim.1994.1027. http://dx.doi.org/10.1006/fsim.1994.1027...
|
Anguillicola crassus
|
Anguilla anguilla
|
Specific antibody production in response to cuticle and gonad antigens; |
Nielsen & Buchmann (1997)Nielsen ME, Buchmann K. Glutathione-s-transferase is an important antigen in the eel nematode Anguillicola crassus. J Helminthol 1997; 71(4): 319-324. http://dx.doi.org/10.1017/S0022149X00016138. PMid:9443950. http://dx.doi.org/10.1017/S0022149X00016...
|
Anguillicola crassus
|
Anguilla japonica;
Anguilla anguilla
|
Specific antibody production; Acquired resistance post-immunization in Anguilla japonica;
|
Knopf & Lucius (2008)Knopf K, Lucius R. Vaccination of eels (Anguilla japonica and Anguilla anguilla) against Anguillicola crassus with irradiated L 3. Parasitology 2008; 135(5): 633-640. http://dx.doi.org/10.1017/S0031182008004162. PMid:18302804. http://dx.doi.org/10.1017/S0031182008004...
|
Anisakis simplex
|
Oncorhynchus mykiss
|
Suppression of IgM transcription, increased expression of CD4 and complement factor C3; |
Haarder et al. (2013)Haarder S, Kania PW, Bahlool QZ, Buchmann K. Expression of immune relevant genes in rainbow trout following exposure to live Anisakis simplex larvae. Exp Parasitol 2013; 135(3): 564-569. http://dx.doi.org/10.1016/j.exppara.2013.09.011. PMid:24051344. http://dx.doi.org/10.1016/j.exppara.2013...
|
(e)
|
Parasite |
Species |
Host |
Immune response |
Reference |
Acanthocephala
|
Dentitruncus truttae
|
Salmo trutta
|
Increased number of master cells and fibroblasts expressing proliferation cell nuclear antigen (PCNA); |
Dezfuli et al. (2012)Dezfuli BS, Giari L, Lui A, Squerzanti S, Castaldelli G, Shinn AP, et al. Proliferative cell nuclear antigen (PCNA) expression in the intestine of Salmo trutta trutta naturally infected with an acanthocephalan. Parasit Vectors 2012; 5(1): 198. http://dx.doi.org/10.1186/1756-3305-5-198. PMid:22967751. http://dx.doi.org/10.1186/1756-3305-5-19...
|
Pomphorhynchus kashmirensis
|
Schizothorax sp. |
Antibody production in response to somatic antigens; |
Nazir et al. (2013)Nazir S, Ali MN, Chishti MZ. Purification and Characterization of Pomphorhynchus kashmirensis Somatic Antigens Collected from Naturally Infected Local Fish Schizothorax. N Y Sci J 2013; 6(7): 24-28.
|
Acanthocephalus lucii
|
Esox lucius
|
Master cells immunoreactive to piscidin-3, lysozyme, interleukin-6, TNF - α, met-enkephalin;
|
Dezfuli et al. (2018)Dezfuli BS, Giari L, Lorenzoni M, Carosi A, Manera M, Bosi G. Pike intestinal reaction to Acanthocephalus lucii (Acanthocephala): immunohistochemical and ultrastructural surveys. Parasit Vectors 2018; 11(1): 424. http://dx.doi.org/10.1186/s13071-018-3002-6. PMid:30012189. http://dx.doi.org/10.1186/s13071-018-300...
|