Brazilian Journal of Pharmaceutical Sciences
Print version ISSN 1984-8250
SILVA, Wilson Gomes da; CORTESI, Nicoletta and FUSARI, Paola. Copaiba oleoresin: evaluation of the presence of polycyclic aromatic hydrocarbons (PAHs). Braz. J. Pharm. Sci. [online]. 2010, vol.46, n.3, pp. 597-602. ISSN 1984-8250. http://dx.doi.org/10.1590/S1984-82502010000300025.
The copaiba oleoresin extracted by perforating the tree-trunk found in the Amazonian forest has been used by the native indigenous communities to treat several diseases and also as fuel for lighting and for the motorboats plying the region's rivers. Currently, the oleoresin is mostly employed as a traditional remedy, mainly for the treatment of tonsillitis and as an anti-inflammatory and healing agent in oil and capsule forms, and is also used in several industry sectors. Due to its use in oral form, especially as a traditional remedy, an analysis of the presence of polycyclic aromatic hydrocarbons (PAHs) as contaminants in the oleoresin was performed. PAHs are substances formed by two or more benzoic rings and found in the atmosphere as a residue from incomplete combustion of petroleum derivatives and industrial activities. These substances are found everywhere on land and water, and as a consequence can also be found in vegetables and foodstuffs in general. The use of products contaminated with these substances can compromise human and animal life. This study was performed on oleoresin from different areas or regions in the Amazon, using the HPLC methodology with fluorescence detection. The samples analyzed revealed different concentrations of these compounds.
Keywords : Copaiba [oil]; Copaiba [qualitative analysis]; Polycyclic aromatic hydrocarbons; High performance liquid chromatography [qualitative analysis]; Amazônia [traditional remedy].