Brazilian Journal of Pharmaceutical Sciences
Print version ISSN 1984-8250
ZUBIOLI, Arnaldo et al. Comparative performance of lab tests and blood testing device to monitor glucose, total cholesterol and triacylglycerol in type 2 diabetic patients. Braz. J. Pharm. Sci. [online]. 2011, vol.47, n.3, pp.615-621. ISSN 1984-8250. http://dx.doi.org/10.1590/S1984-82502011000300020.
The performance of lab tests (LT) and blood testing devices (BTD) to monitor glycemia vs. glycated hemoglobin A1c (A1c) were compared. In addition, the performance of blood glucose, total cholesterol (TC) and triacylglycerol measured by LT and BDT were compared. All parameters were measured based on the same blood samples from overnight fasted type 2 diabetic patients (T2DP). Linear regression analysis was used for all comparisons. The results showed that A1c correlated better with LT-glucose (r = 0.58) than BTD-glucose (r = 0.42). Moreover, LT vs. BTD showed r values of 0.90, 0.82 and 0.92 for glucose, TC and triacylglycerol, respectively. It was concluded that the performance of LT-glucose was better than BDT-glucose. Moreover, since triacylycerol and TC measured by BTD correlated better with LT compared to BDT-glucose vs. LT-glucose, the inclusion of BTD-TC and BTD-triacylglycerol for detecting and monitoring hyperlipidemia in T2DP should be considered.
Keywords : Laboratory tests; Glycated hemoglobin; Glycemia; Total cholesterol; Triacylglycerol; Type 2 diabetes.