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Brazilian Journal of Pharmaceutical Sciences

On-line version ISSN 2175-9790


CABRAL, Ingridy Simone Ribeiro et al. The correlation between the phenolic composition and biological activities of two varieties of Brazilian propolis (G6 and G12). Braz. J. Pharm. Sci. [online]. 2012, vol.48, n.3, pp.557-564. ISSN 2175-9790.

Biological assays that have been performed on different types of Brazilian propolis have shown that type 6 propolis (G6) has a strong antimicrobial activity and a low flavonoid content. This study aimed to evaluate the correlation between the phenolic composition and the biological activities displayed by propolis G6 from the state of Bahia and green propolis, also known as type 12 (G12). The values of the flavonoids and the total phenolics in propolis G6 were different than those in propolis G12. Although the G12 variety presented greater antioxidant activity, propolis G6 proved to have greater antimicrobial and cytotoxic activities. The results showed that the phenolic compounds may not be the only compounds responsible for the biological activity. More detailed studies of the chemical composition and an assessment of the biological activity are required to establish the quality of propolis.

Keywords : Brazilian própolis [evaluation]; Flavonoids [determination in propolis]; Phenolic compounds [determination in propolis]; Propolis [quality control].

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