SciELO - Scientific Electronic Library Online

 
vol.17 issue3The orthodontist's profile in Minas Gerais author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Dental Press Journal of Orthodontics

On-line version ISSN 2176-9451

Abstract

CONSOLARO, Alberto. Advances in knowledge about induced tooth movement Part 1: the osteocytes. Dental Press J. Orthod. [online]. 2012, vol.17, n.3, pp. 14-18. ISSN 2176-9451.  http://dx.doi.org/10.1590/S2176-94512012000300004.

Osteoblasts and clasts were primary targets for the understanding of bone biopathology. In recent years, evidence has shifted attention to the osteocytes. The biology of induced tooth movement and jaw orthopedics should research the role of osteocytes and the specific effects of mediators such as RANKL and sclerostin. The sclerostin represents a regulatory molecule: When more bone is necessary, osteocytes release less sclerostin, when it is necessary to inhibit bone formation, osteocytes release more sclerostin. RANKL is connected to local osteoclastogenesis in order to have more cells capable of reabsorbing the mineralized matrix. New therapeutic ways of controlling the metabolic bone diseases have been targeted at these mediators.

Keywords : Osteocytes; Mechanotransduction; Tooth movement; Sclerostin; RANKL.

        · text in English     · pdf in English