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Trends in Psychiatry and Psychotherapy

Print version ISSN 2237-6089

Abstract

TOSTES, Márcia Helena Fávero de Souza et al. Fatty acid and phospholipase A2 plasma levels in children with autism. Trends Psychiatry Psychother. [online]. 2013, vol.35, n.1, pp.76-80. ISSN 2237-6089.  http://dx.doi.org/10.1590/S2237-60892013000100009.

OBJECTIVE: To evaluate fatty acid plasma levels, phospholipase A2 activity, and the developmental profiles of children with autism vs. control subjects. METHODS: Twenty four children with autism underwent laboratory analysis for fatty acid quantification using gas chromatography and PLA2 activity determination by fluorometric assay. RESULTS: No correlation was observed between the developmental quotient and fatty acid plasma levels. Phospholipase A2 activity was significantly higher among autistic children compared with controls. CONCLUSION: The study did not show a correlation between fatty acid and phospholipase A2 plasma levels and the developmental profile of children with autism.

Keywords : Autistic disorder; fatty acids; phospholipase A2.

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