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Original article • Epidemiol. Serv. Saúde 26 (2) • Apr-Jun 2017 • https://doi.org/10.5123/S1679-49742017000200015   copy

Prevalence of Kaposi's sarcoma in patients with AIDS and associated factors, São Paulo-SP, Brazil, 2003-2010* * Study funded by Johns Hopkins University (JHU) - ICOORTA - Process Number 3D43TW000010-21S1 - and the American National Institute of Health (NIH/USA) - Process number AI06699 (JEG).

Authorship SCIMAGO INSTITUTIONS RANKINGS

Abstract

OBJECTIVE:

to estimate the prevalence of Kaposi’s sarcoma (KS) in patients with AIDS and identify the associated factors to the occurrence of this neoplasm.

METHODS:

this is a cross-sectional study with notification data from two AIDS reference centers in São Paulo-SP, Brazil, from January, 2003 to March, 2010; probabilistic linkage and multiple logistic regression methods were applied.

RESULTS:

among 3,557 AIDS cases, 213 (6%) presented KS; 95.3% of them occurred in males; male sex (OR=3.1; 95%CI=1.4;6.6), age at the AIDS diagnosis >28 years old (OR=1.6; 95%CI=1.0;2.6), MSM (OR=3.2; 95%CI=2.0;4.9), prior use of HAART (OR=0.4; 95%CI=0.3;0.5), AIDS diagnosis between 2007-2010 (OR=0.3; 95%CI=0.2;0.4), and CD4+ T-cell counting under 200cells/mm3 (OR=16.0; 95%CI=6.0;42.7) and 200-500cells/mm³ (OR=2,5; 95%CI=1.1;6.4) were associated to the occurrence of KS.

CONCLUSION:

KS has a high prevalence in São Paulo-SP; strategies for early HIV diagnosis may reduce this prevalence.

Keywords:
Acquired Immunodeficiency Syndrome; Kaposi's Sarcoma; Highly Active Antiretroviral Therapy; Epidemiology, Descriptive

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