Expansão da circulação do vírus Zika da África à América, 1947-2018: revisão da literatura

Sampaio, Gilmara de Souza; Brites, Carlos; Drexler, Jan Felix; Moreira-Soto, Andres; Miranda, Fernanda; Martins Netto, Eduardo

doi:10.5123/S1679-49742019000200022

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Epidemiologia e Serviços de Saúde

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Sumário

REVISÃO NARRATIVA • Epidemiol. Serv. Saúde 28 (2) • 2019 • https://doi.org/10.5123/S1679-49742019000200022 copiar

Expansão da circulação do vírus Zika da África à América, 1947-2018: revisão da literatura^* * Artigo derivado de tese de doutorado intitulada ‘Dispersão, prevalência e dinâmica da transmissão do vírus Zika, de 1947 a 2018’, defendida por Gilmara de Souza Sampaio junto ao Programa de Pós-Graduação em Ciências da Saúde da Faculdade de Medicina da Universidade Federal da Bahia, em 21 de março de 2019.

Expansión de la circulación del virus Zika de África a América, 1947-2018: una revisión de literatura

Autoria SCIMAGO INSTITUTIONS RANKINGS

Resumo

Objetivo:

descrever as expansões temporal e geográfica da circulação do vírus Zika (ZIKV) em países e territórios, desde seu isolamento até 2018.

Métodos:

revisão não sistemática da literatura do período entre 1947 e 2018, utilizando a base MEDLINE e estimativas da Organização Mundial da Saúde.

Resultados:

desde seu isolamento em 1947, a circulação do ZIKV expandiu-se pela África, Ásia e Pacífico, até chegar à América em 2013, causando manifestações clínicas graves; as maiores soroprevalências foram registradas na ilha de Yap (74%) e no Brasil (63%); mutações genéticas, a ausência de imunidade e a alta susceptibilidade dos vetores podem ter influenciado sua transmissibilidade e ajudam a explicar a magnitude de sua expansão.

Conclusão:

a expansão da circulação do ZIKV nas Américas foi a mais ampla já registrada, possivelmente resultado de características populacionais e geográficas dos locais por onde o vírus circulou.

Palavras-chave:
Zika virus; Flavivírus; Epidemiologia; Epidemias; Anormalidades Congênitas; Literatura de Revisão como Assunto

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[1] Endereço para correspondência: Gilmara de Souza Sampaio - Universidade Federal da Bahia, Hospital Universitário Edgard Santos, Laboratório de Pesquisa em Infectologia, Rua João das Botas, n^o 157b, Canela, Salvador, BA, Brasil. CEP: 40110-160 E-mail: gilmara.s.sampaio@hotmail.com