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MedicalExpress

Print version ISSN 2318-8111On-line version ISSN 2358-0429

Abstract

RIO, Rute et al. The biochemistry of saliva throughout pregnancy. MedicalExpress (São Paulo, online) [online]. 2015, vol.2, n.5, M150506. ISSN 2358-0429.  https://doi.org/10.5935/MedicalExpress.2015.05.06.

BACKGROUND & OBJECTIVE:

Sialometric and sialochemical analyses during pregnancy are not consistent, and frequently contradictory in terms of salivary flow rate, pH, and concentration of calcium, phosphorous, sodium, potassium, chloride, glucose and α-amylase. We, therefore, measured the evolution of these parameters throughout pregnancy.

METHOD:

A cross-sectional study compared sialometric and sialochemical analyses of 30 pregnant women vs. 30 age-matched non-pregnant women, and a longitudinal study evaluated the pregnant women in the first and third trimester of pregnancy.

RESULTS:

Pregnant women presented acidic non-stimulated saliva, but neutral stimulated saliva pH, and no relevant changes in salivary flow rate. Scialochemical analysis showed decreased calcium levels, increased phosphate levels, and a progressive decrease in glucose levels throughout pregnancy.

CONCLUSION:

Pregnancy significantly changes the oral biochemical milieu, creating a favorable environment for the development of oral pathology, in particular, dental caries.

Keywords : Saliva; pregnancy; pH; calcium; phosphorous; glucose.

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