Fear of treatment failure |
Sanderson 2009 [6060. Sanderson T, Calnan M, Morris M, Richards P, Hewlett S. The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study. Musculoskeletal Care. 2009;7(3):194–209.] |
Fear of being taken of a drug |
Sanderson 2009 [6060. Sanderson T, Calnan M, Morris M, Richards P, Hewlett S. The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study. Musculoskeletal Care. 2009;7(3):194–209.] |
Fear of side effects of treatment (mainly long- term side effects) |
Goodacre 2004 [44. Goodacre LJ, Goodacre JA. Factors influencing the beliefs of patients with rheumatoid arthritis regarding disease-modifying medication. Rheumatology. 2004;43(5):583–6.] Popa-Lisseanu 2005 [6161. Popa-Lisseanu MGG, Greisinger A, Richardson M, O'Malley KJ, Janssen NM, Marcus DM, et al. Determinants of treatment adherence in ethnically diverse, economically disadvantaged patients with rheumatic disease. J Rheumatol. 2005;32(5):913–9.] Wong 2007 [55. Wong M, Mulherin D. The influence of medication beliefs and other psychosocial factors on early discontinuation of disease-modifying antirheumatic drugs. Musculoskeletal Care. 2007;5(3):148–59.] Sanderson 2009 [6060. Sanderson T, Calnan M, Morris M, Richards P, Hewlett S. The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study. Musculoskeletal Care. 2009;7(3):194–209.] Fitzcharles 2009 [6262. Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. J Pain. 2009;10(3):300–5.] Kumar 2011 [4343. Kumar K, Gordon C, Barry R, Shaw K, Horne R, Raza K. “It's like taking poison to kill poison but I have to get better”: a qualitative study of beliefs about medicines in rheumatoid arthritis and systemic lupus erythematosus patients of south Asian origin. Lupus. 2011;20(8):837–44.] Van den Bent 2011 [6363. Van Den Bemt BJF, Den Broeder AA, Van Den Hoogen FHJ, Benraad B, Hekster YA, Van Riel PLCM, et al. Making the rheumatologist aware of patients' non-adherence does not improve medication adherence in patients with rheumatoid arthritis. Scand J Rheumatol. 2011;40(3):192–6.] Hayden 2015 [1414. Hayden C, Neame R, Tarrant C. Patients' adherence-related beliefs about methotrexate: a qualitative study of the role of written patient information. BMJ Open. 2015;5(5):e006918.] Gadallah 2015 [4242. Gadallah MA, Boulos DNK, Gebrel A, Dewedar S, Morisky DE. Assessment of rheumatoid arthritis patients' adherence to treatment. Am J Med Sci. 2015; 349(2):151-6.] Pasma 2015 [1515. Pasma A, Van't Spijker A, Luime JJ, Walter MJM, Busschbach JJV, Hazes JMW. Facilitators and barriers to adherence in the initiation phase of diseasemodifying antirheumatic drug (DMARD) use in patients with arthritis who recently started their first DMARD treatment. J Rheumatol. 2015;42(3):379–85.] Nota 2015 [6464. Nota I, Drossaert CHC, Taal E, Van De Laar MAFJ. Patients' considerations in the decision-making process of initiating disease-modifying antirheumatic drugs. Arthritis Care Res. 2015;67(7):956–64.] |
Fear of ‘too many pills/too many drugs”, fear of over-prescription |
Popa-Lisseanu 2005 [6161. Popa-Lisseanu MGG, Greisinger A, Richardson M, O'Malley KJ, Janssen NM, Marcus DM, et al. Determinants of treatment adherence in ethnically diverse, economically disadvantaged patients with rheumatic disease. J Rheumatol. 2005;32(5):913–9.] Wong 2007 [55. Wong M, Mulherin D. The influence of medication beliefs and other psychosocial factors on early discontinuation of disease-modifying antirheumatic drugs. Musculoskeletal Care. 2007;5(3):148–59.] Fitzcharles 2009 [6262. Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. J Pain. 2009;10(3):300–5.] |
Fear of drug interaction |
Fitzcharles 2009 [6262. Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. J Pain. 2009;10(3):300–5.] |
Fear of addiction |
Goodacre 2004 [44. Goodacre LJ, Goodacre JA. Factors influencing the beliefs of patients with rheumatoid arthritis regarding disease-modifying medication. Rheumatology. 2004;43(5):583–6.] Wong 2007 [55. Wong M, Mulherin D. The influence of medication beliefs and other psychosocial factors on early discontinuation of disease-modifying antirheumatic drugs. Musculoskeletal Care. 2007;5(3):148–59.] Sanderson 2009 [6060. Sanderson T, Calnan M, Morris M, Richards P, Hewlett S. The impact of patient-perceived restricted access to anti-TNF therapy for rheumatoid arthritis: a qualitative study. Musculoskeletal Care. 2009;7(3):194–209.] Fitzcharles 2009 [6262. Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. J Pain. 2009;10(3):300–5.] Kumar 2011 [4343. Kumar K, Gordon C, Barry R, Shaw K, Horne R, Raza K. “It's like taking poison to kill poison but I have to get better”: a qualitative study of beliefs about medicines in rheumatoid arthritis and systemic lupus erythematosus patients of south Asian origin. Lupus. 2011;20(8):837–44.] Van den Bent 2011 [6363. Van Den Bemt BJF, Den Broeder AA, Van Den Hoogen FHJ, Benraad B, Hekster YA, Van Riel PLCM, et al. Making the rheumatologist aware of patients' non-adherence does not improve medication adherence in patients with rheumatoid arthritis. Scand J Rheumatol. 2011;40(3):192–6.] Nota 2015 [6464. Nota I, Drossaert CHC, Taal E, Van De Laar MAFJ. Patients' considerations in the decision-making process of initiating disease-modifying antirheumatic drugs. Arthritis Care Res. 2015;67(7):956–64.] |
Fear of masking disease |
Fitzcharles 2009 [6262. Fitzcharles MA, DaCosta D, Ware MA, Shir Y. Patient barriers to pain management may contribute to poor pain control in rheumatoid arthritis. J Pain. 2009;10(3):300–5.] |
Fear of drugs causing reduced life expectancy |
Goodacre 2004 [44. Goodacre LJ, Goodacre JA. Factors influencing the beliefs of patients with rheumatoid arthritis regarding disease-modifying medication. Rheumatology. 2004;43(5):583–6.] |
Fear of being disappointed with a new treatment |
Nyman 1999 [4646. Nyman CS, Lutzen K. Caring needs of patients with rheumatoid arthritis. Nurs Sci Q. 1999;12(2):164–9.] |
Fear of too many changes in therapy |
Kumar 2011 [4343. Kumar K, Gordon C, Barry R, Shaw K, Horne R, Raza K. “It's like taking poison to kill poison but I have to get better”: a qualitative study of beliefs about medicines in rheumatoid arthritis and systemic lupus erythematosus patients of south Asian origin. Lupus. 2011;20(8):837–44.] |