Abstracts
Mycobacterium avium complex (MAC) is frequently isolated from patients with late complications of Acquired Immunodeficiency Syndrome (AIDS), especially in North America and Europe. However, its isolation from the central nervous system (CNS) has been seldom reported in these countries. MAC infections in AIDS patients in African and Latin American countries are believed to be uncommon. We report the isolation of MAC from cerebrospinal fluid (CSF) of 11 AIDS patients out of 1723 (0.63%) seen at "Centro de Referência e Treinamento - AIDS", São Paulo and discuss the significance of its isolation.
Mycobacterium avium complex (MAC); Cerebrospinal fluid (CSF); Acquired immunodeficiency syndrome (AIDS)
O complexo Mycobacterium avium (CMA) é frequentemente isolado de pacientes com complicações tardias de Síndrome de Imunodeficiência Adquirida (AIDS), especialmente na América do Norte e Europa. Entretanto, existem poucos relatos do isolamento deste complexo a partir do sistema nervoso central (SNC) nestes países. Acredita-se que infecções pelo CMA sejam raras entre pacientes portadores de AIDS em países da África e América Latina. Neste trabalho relatamos o isolamento do CMA do líquor de 11 pacientes portadores de AIDS dentre 1723 (0.63%) atendidos no Centro de Referência e Treinamento -AIDS, de São Paulo, e discutimos a significância deste achado.
MICROBIOLOGY
Mycobacterium avium complex (MAC): an unusual potential pathogen in cerebrospinal fluid of AIDS patients
Complexo Mycobacterium avium: um patógeno potencial pouco comum no líquido céfalo -raquidiano de pacientes com AIDS
David Jamil HadadI; Tereza Cristina PetryII; Anaenza Freie MarescaIII; Lucilaine FerrazoliIV; Maria Conceição MartinsIV; Maria Cecilia de Almeida PalharesV; Walkyria Pereira PintoVI; Adauto Castelo FilhoVII; Moises PalaciIV
IMédico infectologista do Centro de Referência e Treinamento AIDS (CRTA), Mestre em Doenças Infecciosas e Parasitárias pela Escola Paulista de Medicina
IIMédico Infectologista do CRTA
IIIEx-Infectologista do CRTA
IVPesquisadores Científicos do Setor de Micobactérias do Instituto Adolfo Lutz
VChefe do Laboratório do CRTA
VIDiretora Técnica do CRTA
VIIProfessor Adjunto da Disciplina de Doenças Infecciosas e Parasitárias da Escola Paulista de Medicina
Correspondence to Correspondence to: David Jamil Hadad Rua Dr. Diogo de Faria, 666/35 Vila Clementino, 04037-222 São Paulo, S.P., Brasil
SUMMARY
Mycobacterium avium complex (MAC) is frequently isolated from patients with late complications of Acquired Immunodeficiency Syndrome (AIDS), especially in North America and Europe. However, its isolation from the central nervous system (CNS) has been seldom reported in these countries. MAC infections in AIDS patients in African and Latin American countries are believed to be uncommon. We report the isolation of MAC from cerebrospinal fluid (CSF) of 11 AIDS patients out of 1723 (0.63%) seen at "Centro de Referência e Treinamento - AIDS", São Paulo and discuss the significance of its isolation.
Keywords:Mycobacterium avium complex (MAC); Cerebrospinal fluid (CSF); Acquired immunodeficiency syndrome (AIDS).
RESUMO
O complexo Mycobacterium avium (CMA) é frequentemente isolado de pacientes com complicações tardias de Síndrome de Imunodeficiência Adquirida (AIDS), especialmente na América do Norte e Europa. Entretanto, existem poucos relatos do isolamento deste complexo a partir do sistema nervoso central (SNC) nestes países. Acredita-se que infecções pelo CMA sejam raras entre pacientes portadores de AIDS em países da África e América Latina. Neste trabalho relatamos o isolamento do CMA do líquor de 11 pacientes portadores de AIDS dentre 1723 (0.63%) atendidos no Centro de Referência e Treinamento -AIDS, de São Paulo, e discutimos a significância deste achado.
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ACKNOWLEDGEMENTS
We are grateful to Prof. Dr. Gildo Del Negro, from Faculdade de Medicina - Universidade de São Paulo, for his critical review of this manuscript.
Recebido para publicação em 05/09/1994
Aceito para publicação em 20/09/1994
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Publication Dates
-
Publication in this collection
22 Feb 2007 -
Date of issue
Apr 1995
History
-
Accepted
20 Sept 1994 -
Received
05 Sept 1994