Associação entre retinopatia da prematuridade e hemorragia intraventricular em recém-nascidos pré-termo e de baixo peso

Tavano, Valéria; Moraes, Nilva S. B.; Almeida, Maria Fernanda B. de; Farah, Michel Eid

doi:10.5935/0004-2749.19980095

RESUMO

Foram estudadas prospectivamente 71 crianças pré-termo nascidas no Hospital São Paulo durante o ano dei 995. A análise das observações referentes ao peso ao nascer, idade gestacional, oftalmoscopia, e exame de ultrassom de fontanela dos recém-nascidos, revelou uma relação estatisticamente significante entre retinopatia da prematuridade (RP), baixo peso ao nascimento (796,6 g), menor idade gestacional (média de 28,3 semanas) e hemorragia intraventricular (HV), sugerindo um possível mecanismo fisiopatológico vascular comum para RP e HV.

Palavras-chave:
Retinopatia da prematuridade; Hemorragia intraventricular; Recém-nascido pré-termo; Unitermo

SUMMARY

A total of 71 preterm infants born in 1995 at the São Paulo Hospital were prospectively studied. The analysis of the relation among weight, gestational age, fundus examination and fontanelas ultrasound showed a statistically significant relation between retinopathy of prematurity (RP), low birth weight (796.6 g), small gestational age (28.3 weeks) and intraventricular hemorrhage (HV), suggesting a possible common physiophathological mechanism to RP and HV.

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REFERÊNCIAS BIBLIOGRÁFICAS

¹
McCormick AQ. Retinopathy of prematurity. In: Gluck L, ed. Current Problems in pediatrics. Vol VII (11). Chicago: Year Book Medical Publishers lnc, 1977.
²
Hamblenton, G.; Wigglesworth, J. S. - Origin of intraventricular hemorrhage in preterm infant. Arch Chil 1976;51:651-9.
³
Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with weights less than 1500g. J Pediatr 1978;92:529-34.
⁴
Lou HC, Lassen NA, Friis-Hansen B. lmpaired autoregulation of cerebral blood flow in the distressed newbom infant. J Pediatr 1979;94: 118-21.
⁵
James LS, Lanman JT. History ofoxygen therapy and retrolental fibroplasia. Pediatrics 1976;57:591-642.
⁶
Tsacopoulous M, David NJ. The effect of arterial Pco2 on relative retinal blood flow in monkeys. Invest Ophthalmol 1973;12:335-47.
⁷
Procianoy SR, Garcia-Prats JA, Hittner MH, Rudolf JA. An association between retinopathy of prematurity and intraventricular hemorrhage in very low birth weight infants. Acta Paediatr Scand 1981;70:473-7.
⁸
The Committee for the Classification of Retinopathy of Prematurity: An international classification of retinopathy of prematurity Arch Ophthalmol 1984;102:1130-4.
⁹
Bada HS, Hajjar W, Chua C, Sumner DS. Non invasive diagnosis of neonatal asphyxia and intraventricular hemorrhage by doppler ultrasound. J Pediatr 1979;95:775-9.
¹⁰
Hungerford, J.; Stewart, A; Hope, P. Ocular sequel of preterm and their relation to ultrasound evidence of cerebral damage. British J Ophthal, 1986;70:463-8.

Datas de Publicação

Publicação nesta coleção
Feb 1998

Este é um artigo publicado em acesso aberto (Open Access) sob a licença Creative Commons Attribution, que permite uso, distribuição e reprodução em qualquer meio, sem restrições desde que o trabalho original seja corretamente citado.

[1] ¹
McCormick AQ. Retinopathy of prematurity. In: Gluck L, ed. Current Problems in pediatrics. Vol VII (11). Chicago: Year Book Medical Publishers lnc, 1977.

[2] ²
Hamblenton, G.; Wigglesworth, J. S. - Origin of intraventricular hemorrhage in preterm infant. Arch Chil 1976;51:651-9.

[3] ³
Papile LA, Burstein J, Burstein R, Koffler H. Incidence and evolution of subependymal and intraventricular hemorrhage: A study of infants with weights less than 1500g. J Pediatr 1978;92:529-34.

[4] ⁴
Lou HC, Lassen NA, Friis-Hansen B. lmpaired autoregulation of cerebral blood flow in the distressed newbom infant. J Pediatr 1979;94: 118-21.

[5] ⁵
James LS, Lanman JT. History ofoxygen therapy and retrolental fibroplasia. Pediatrics 1976;57:591-642.

[6] ⁶
Tsacopoulous M, David NJ. The effect of arterial Pco2 on relative retinal blood flow in monkeys. Invest Ophthalmol 1973;12:335-47.

[7] ⁷
Procianoy SR, Garcia-Prats JA, Hittner MH, Rudolf JA. An association between retinopathy of prematurity and intraventricular hemorrhage in very low birth weight infants. Acta Paediatr Scand 1981;70:473-7.

[8] ⁸
The Committee for the Classification of Retinopathy of Prematurity: An international classification of retinopathy of prematurity Arch Ophthalmol 1984;102:1130-4.

[9] ⁹
Bada HS, Hajjar W, Chua C, Sumner DS. Non invasive diagnosis of neonatal asphyxia and intraventricular hemorrhage by doppler ultrasound. J Pediatr 1979;95:775-9.

[10] ¹⁰
Hungerford, J.; Stewart, A; Hope, P. Ocular sequel of preterm and their relation to ultrasound evidence of cerebral damage. British J Ophthal, 1986;70:463-8.

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