ABSTRACT
BACKGROUND
Morbid obesity is a multifactorial disease that is increasingly treated by surgery.
OBJECTIVE
To evaluate gastric histopathological changes in obese, and to compare with patients who underwent gastrojejunal bypass and the jejunal mucosa after the surgery.
METHODS
This is an observational study performed at a tertiary public hospital, evaluating endoscopic biopsies from 36 preoperative patients and 35 postoperative.
RESULTS
In the preoperative group, 80.6% had chronic gastritis, which was active in 38.9% (77.1% and 20.1%, respectively, in the postoperative). The postoperative group had a significant reduction in Helicobacter pylori infection (P=0.0001). A longer length of the gastric stump and a time since surgery of more than two years were associated with Helicobacter pylori infection. The jejunal mucosa was normal in 91.4% and showed slight nonspecific chronic inflammation in 8.6%.
CONCLUSION
There was a reduction in the incidence of Helicobacter pylori infection in the postoperative group. A longer length of the gastric stump and longer time elapsed since surgery were associated with Helicobacter pylori infection. The jejunal mucosa was considered normal in an absolute majority of patients.
Headings:
Obesity; Bariatric surgery; Histology; Gastritis; Helicobacter pylori
RESUMO
CONTEXTO
A obesidade mórbida é doença multifatorial cujo tratamento cirúrgico é cada vez mais indicado.
OBJETIVO
Avaliar alterações histopatológicas gástricas em obesos e comparar com os submetidos à bypass gastrojejunal e a mucosa jejunal após a operação.
MÉTODOS
Estudo observacional realizado em hospital público terciário avaliando biópsias endoscópicas de 36 pacientes no pré-operatório e 35 no pós-operatório.
RESULTADOS:
No pré-operatório 80,6% apresentaram gastrite crônica, 38,9% em atividade (77,1% e 20,1%, respectivamente, no pós-operatório). O grupo pós-operatório apresentou diminuição significativa na infecção por Helicobacter pylory (P=0,0001). Maior comprimento do coto gástrico e tempo de operação superior a dois anos associaram-se a infecção por Helicobacter pylori. A mucosa jejunal foi normal em 91,4% e apresentava leve inflamação crônica inespecífica em 8,6%.
CONCLUSÃO
Houve diminuição da infecção por Helicobacter pylori após a operação. Maior comprimento do coto gástrico e do tempo de operação associaram-se à infecção por Helicobacter pylori. A mucosa jejunal foi considerada normal na maioria absoluta dos pacientes do grupo pós-operatório.
Descritores:
Obesidade; Cirurgia bariátrica; Histologia; Gastrite; Helicobacter pylori
The Editorial Board of Archives of Gastroenterology, ISSN 1678-4219 online, decided, after analysis, to retract the article following:
Rodrigues RSN, Almeida ECS, Terra Júnior JA, Guimarães LC, Duque ACR, Etchebehere RM. Gastric and jejunal histopathological changes in patients undergoing bariatric surgery. Arq Gastroenterol. 2017,54(1):75-8. doi: 10.1590/S0004-2803.2017v54n1-15.
The submission process is based on the authors’ ethics in ensuring exclusivity to a single journal. There are no means of submission and publication duplicity control in two jornals in near dates.
Publication Dates
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Publication in this collection
Jan-Mar 2017
History
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Received
06 Sept 2016 -
Accepted
13 Sept 2016
