Manifestações clínicas da epilepsia temporal observadas durante a ativação pelo cardiazol

Ribeiro, Rubens Moura

doi:10.1590/S0004-282X1963000300005

Resumos

Foram analisados, do ponto de vista clínico e eletrencefalográfico, 25 pacientes portadores de epilepsia temporal com a finalidade de comparar a sintomatologia clínica evidenciada através da ativação pelo cardiazol com os achados eletrencefalográficos obtidos simultâneamente. Para facilidade do estudo, os pacientes foram divididos em grupos de acôrdo com a sintomatologia clínica. A eclosão de cada sintoma foi analisada objetivamente utilizando a ativação pelo cardiazol em doses fracionadas. Com isso foi possível estabelecer uma seqüência entre o quadro clínico e as alterações eletrencefalográficas. Em cada um dos casos estudados os resultados foram comparados com aqueles referidos na literatura.

Based on the metrazol activation of 25 cases of temporal lobe epilepsy, the author analyzes the varied clinical manifestations and electroencephalo- graphic sequence. In order to appreciate more readily the various patterns of temporal lobe seizures the major types of manifestations have been grouped in separate tabulations. The material suggests that there may be an ordered arrangement of certain clinical and electroencephalographic patterns concerned the temporal lobe.

Rubens Moura Ribeiro

Assistente. Trabalho da Clínica Neurológica da Fac. Med. de Ribeirão Prêto, da Univ. de São Paulo (Prof. Jorge Armbrust-Figueiredo)

RESUMO

Foram analisados, do ponto de vista clínico e eletrencefalográfico, 25 pacientes portadores de epilepsia temporal com a finalidade de comparar a sintomatologia clínica evidenciada através da ativação pelo cardiazol com os achados eletrencefalográficos obtidos simultâneamente. Para facilidade do estudo, os pacientes foram divididos em grupos de acôrdo com a sintomatologia clínica. A eclosão de cada sintoma foi analisada objetivamente utilizando a ativação pelo cardiazol em doses fracionadas. Com isso foi possível estabelecer uma seqüência entre o quadro clínico e as alterações eletrencefalográficas. Em cada um dos casos estudados os resultados foram comparados com aqueles referidos na literatura.

SUMMARY

Based on the metrazol activation of 25 cases of temporal lobe epilepsy, the author analyzes the varied clinical manifestations and electroencephalo- graphic sequence. In order to appreciate more readily the various patterns of temporal lobe seizures the major types of manifestations have been grouped in separate tabulations. The material suggests that there may be an ordered arrangement of certain clinical and electroencephalographic patterns concerned the temporal lobe.

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Clínica Neurológica, Faculdade de Medicina - Ribeirão Prêto, São Paulo - Brasil

1. AJMONE-MARSAN, C; RALSTON, B. L. - The Epileptic Seizure. A Clinical-Electrographic Analysis of Metrazol-induced attacks. Charles C. Thomas, Springfield (Illinois), 1957.
2. AJMONE-MARSAN, C; van BUREN, J. M. - Epileptiform activity in cortical and subcortical structure in the temporal lobe of man. In Temporal Lobe Epilepsy edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois) 1958.
3. ARMBRUST-FIGUEIREDO, J. - Contribuição ao Estudo Clínico da Epilepsia Temporal. Tese de docência. Escola Paulista de Medicina, 1958.
4. BALDWIN, M.; FROST, L. L.; WOOD, C. D. - Investigation of the primate amygdala. Neurology 4:586-593, 1954.
5. BRANDT, H. A.; JEUB, R. P. - Definitive diagnosis in loss consciousness: Further experience with metrazol activation. Dis. Nerv. System 17:43-47, 1956.
6. BROSER, F.; HANN, J.; LEUBE, H. - Die perorale Cardiozolmedikation als Epilepsietest: Untersuchungen an Epileptiken unter EEG-Kontrolle. Nervenarzt 22:351-353, 1951.
7. CURE, C; RASMUSSEN, T.; JASPER, H. - Activation of seizures and electroencephalographic disturbances in epileptic and in control subjects with metrazol. Arch. Neurol. & Psychiat., 59:691-717, 1948.
8. DELL, M. B. - L'epilepsie temporale. Presse Med., 61:505-508, 1953.
9. FUGLSANG-FREDERIKSEN, V. - Activation of EEG disturbances with Metrazol (Pentazol) in epileptics, normals and patients with syncopal attacks. Electroence-phalog. & Clin. Neurophysiol., 4:471-480, 1952.
10. GASTAUT, H.; NAQUET, R.; MEYER, A.; CAVANAGH, J. B.; BECK, E. - Clinical, Electroencephalographic and Anatomo-Pathological Study of "Psychomotor" Epilepsy Induced in the Cat. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.
11. GASTAUT, H.; TOG, M.; NAQUET, R. - Clinical electrographical and anatomical study of epilepsy induced in dog by the ingestion of agenized proteins. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.
12. GASTAUT, H.; VIGOROUX, M. - Electroclinical correlations in 500 cases of psychomotor seizures. In Temporal Lobe Epilepsy, edit. por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.
13. GIBBS, E. L.; GIBBS, F. A.; FUSTER, B. - Psychomotor epilepsy. Arch. Neurol. & Psychiat., 60:331-339, 1948.
14. GIBBS, F. A.; STAMPS, F. W. - Epilepsy Handbook. Charles C. Thomas, Springfield (Illinois), 1958.
15. JONES, E.; BAGCHI, B. K. - Orally administered metrazol combined with photic stimulation as an EEG activating procedure. Electroencephalog. & Clin. Neurophysiol., 6:696-697, 1954.
16. KAUFMAN, F. C; MARSHALL, C; WALKER, A. E. - Metrazol activated electroencephalography. Proc. Am. Res. Nerv. & Ment. Dis., 26:476, 1957.
17. MERLIS, J. K.; GROSSMAN, C; HENRICKSEN, G. F. - Comparative effectiveness of sleep and Metrazol-activated electroencephalography. Electroencephalog. & Clin. Neurophysiol., 3:71-78, 1951.
18. MERLIS, J. K.; HENRICKSEN, G. F.; GROSSMAN, C. - Metrazol activations of seizures discharges in epileptics with normal routine electroencephalograms. Electroencephalog. & Clin. Neurophysiol., 2:17-22, 1950.
19. MOORE, F. J.; KELLAWAY, P.; KAGAWA, N. - Metrazol activation as a diagnostic adjunct in electroencephalography; a re-evaluation. Neurology 4:325-338, 1954.
20. MULDER, D. M.; DALY, D. - Psychiatric symptoms associated with lesions of temporal lobe. J.A.M.A., 150:173-176, 1952.
21. PAPEZ, J. W. - A proposed mechanism of emotion. Arch. Neurol. & Psychiat., 38:725, 1937.
22. PENFIELD, W. - Epileptic automatism and the centroencephalic integrating system. Proc. Am. Res. Nerv. & Ment. Dis., 30:513-528, 1952.
23. PENFIELD, W.; ERICKSON, T. C. - Epilepsy and Cerebral Localization. Charles C. Thomas, Springfield (Illinois), 1941.
24. PENFIELD, W.; JASPER, H. - Epilepsy and the Functional Anatomy of the Human Brain. Little Brown, Boston, 1954.
25. PEREZ-ACHARD, L.; GARCIA-ARUST, E. - Metrazol activation in epileptic and non-epileptic patients. Eletroencephalog. & Clin. Neurophysiol., 6:536, 1954.
26. PEREZ-ACHARD, L.; GARCIA-ARUST, E.; GALEANO-MUÑOZ, C. - Metrazol activation in epilepsy. Electroencephalog. & Clin. Neurophysiol., 8:153-154, 1956.
27. PUPO, P. P.; ZUKERMAN, E. - Some comparative results of activation methods in electroencephalography. Electroencephalog. & Clin. Neurophysiol., 8:154, 1956.
28. RAS-MUSSEN, T.; JASPER, H. - Temporal lobe epilepsy: indication for operation and surgical technique. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.
29. SMITH, B.; FAZEKAS, J.; FORSTER, F. M.; SMITH, G. E. - Activation of the electroencephalogram with oral pentylenetetrazol. Proc. III Internat. Congress EEG Clin. Neurophysiol., Cambridge (Mass.), 1953.
30. STEVENS, J. R. - The "march" of temporal lobe epilepsy. Arch. Neurol. & Psychiat., 77:227-236, 1957.
31. STROBOS, R. J. - Mechanims in temporal lobe seizures. Arch. Neurol., 5:36-45, 1961.
32. TOWER, D. B. - The evidence for a neurochemical basis of seizures. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.
33. VICTOR, M.; ANGEVINE, V.; MANCALL, E. L.; FISHER, C. M. - Memoryloss with lesions of hipocampal formation. Arch. Neurol., 5:244-263, 1961.
34. von MEDUNA, L. - Versuche über die biologische Beeinflussung des Ablaufes der Schizophrenia: Campher- und cardiazol Krampfe. Ztschr. Ges. Neurol, u. Psychiat., 152: 235, 1935.
35. WALKER, A. E. - Post-traumatic Epilepsy. Charles C. Thomas, Springfield (Illinois), 1949.
36. WEIL, A. A. - Ietal emotions occurring in temporal lobe dysfunction. Arch. Neurol., 1:87-97, 1959.

Manifestações clínicas da epilepsia temporal observadas durante a ativação pelo cardiazol

Clinical symptoms associated with metrazol activation in temporal lobe epilepsy.

Datas de Publicação

Publicação nesta coleção
21 Ago 2013
Data do Fascículo
Set 1963

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. AJMONE-MARSAN, C; RALSTON, B. L. - The Epileptic Seizure. A Clinical-Electrographic Analysis of Metrazol-induced attacks. Charles C. Thomas, Springfield (Illinois), 1957.

[2] 2. AJMONE-MARSAN, C; van BUREN, J. M. - Epileptiform activity in cortical and subcortical structure in the temporal lobe of man. In Temporal Lobe Epilepsy edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois) 1958.

[3] 3. ARMBRUST-FIGUEIREDO, J. - Contribuição ao Estudo Clínico da Epilepsia Temporal. Tese de docência. Escola Paulista de Medicina, 1958.

[4] 4. BALDWIN, M.; FROST, L. L.; WOOD, C. D. - Investigation of the primate amygdala. Neurology 4:586-593, 1954.

[5] 5. BRANDT, H. A.; JEUB, R. P. - Definitive diagnosis in loss consciousness: Further experience with metrazol activation. Dis. Nerv. System 17:43-47, 1956.

[6] 6. BROSER, F.; HANN, J.; LEUBE, H. - Die perorale Cardiozolmedikation als Epilepsietest: Untersuchungen an Epileptiken unter EEG-Kontrolle. Nervenarzt 22:351-353, 1951.

[7] 7. CURE, C; RASMUSSEN, T.; JASPER, H. - Activation of seizures and electroencephalographic disturbances in epileptic and in control subjects with metrazol. Arch. Neurol. & Psychiat., 59:691-717, 1948.

[8] 8. DELL, M. B. - L'epilepsie temporale. Presse Med., 61:505-508, 1953.

[9] 9. FUGLSANG-FREDERIKSEN, V. - Activation of EEG disturbances with Metrazol (Pentazol) in epileptics, normals and patients with syncopal attacks. Electroence-phalog. & Clin. Neurophysiol., 4:471-480, 1952.

[10] 10. GASTAUT, H.; NAQUET, R.; MEYER, A.; CAVANAGH, J. B.; BECK, E. - Clinical, Electroencephalographic and Anatomo-Pathological Study of "Psychomotor" Epilepsy Induced in the Cat. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.

[11] 11. GASTAUT, H.; TOG, M.; NAQUET, R. - Clinical electrographical and anatomical study of epilepsy induced in dog by the ingestion of agenized proteins. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.

[12] 12. GASTAUT, H.; VIGOROUX, M. - Electroclinical correlations in 500 cases of psychomotor seizures. In Temporal Lobe Epilepsy, edit. por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.

[13] 13. GIBBS, E. L.; GIBBS, F. A.; FUSTER, B. - Psychomotor epilepsy. Arch. Neurol. & Psychiat., 60:331-339, 1948.

[14] 14. GIBBS, F. A.; STAMPS, F. W. - Epilepsy Handbook. Charles C. Thomas, Springfield (Illinois), 1958.

[15] 15. JONES, E.; BAGCHI, B. K. - Orally administered metrazol combined with photic stimulation as an EEG activating procedure. Electroencephalog. & Clin. Neurophysiol., 6:696-697, 1954.

[16] 16. KAUFMAN, F. C; MARSHALL, C; WALKER, A. E. - Metrazol activated electroencephalography. Proc. Am. Res. Nerv. & Ment. Dis., 26:476, 1957.

[17] 17. MERLIS, J. K.; GROSSMAN, C; HENRICKSEN, G. F. - Comparative effectiveness of sleep and Metrazol-activated electroencephalography. Electroencephalog. & Clin. Neurophysiol., 3:71-78, 1951.

[18] 18. MERLIS, J. K.; HENRICKSEN, G. F.; GROSSMAN, C. - Metrazol activations of seizures discharges in epileptics with normal routine electroencephalograms. Electroencephalog. & Clin. Neurophysiol., 2:17-22, 1950.

[19] 19. MOORE, F. J.; KELLAWAY, P.; KAGAWA, N. - Metrazol activation as a diagnostic adjunct in electroencephalography; a re-evaluation. Neurology 4:325-338, 1954.

[20] 20. MULDER, D. M.; DALY, D. - Psychiatric symptoms associated with lesions of temporal lobe. J.A.M.A., 150:173-176, 1952.

[21] 21. PAPEZ, J. W. - A proposed mechanism of emotion. Arch. Neurol. & Psychiat., 38:725, 1937.

[22] 22. PENFIELD, W. - Epileptic automatism and the centroencephalic integrating system. Proc. Am. Res. Nerv. & Ment. Dis., 30:513-528, 1952.

[23] 23. PENFIELD, W.; ERICKSON, T. C. - Epilepsy and Cerebral Localization. Charles C. Thomas, Springfield (Illinois), 1941.

[24] 24. PENFIELD, W.; JASPER, H. - Epilepsy and the Functional Anatomy of the Human Brain. Little Brown, Boston, 1954.

[25] 25. PEREZ-ACHARD, L.; GARCIA-ARUST, E. - Metrazol activation in epileptic and non-epileptic patients. Eletroencephalog. & Clin. Neurophysiol., 6:536, 1954.

[26] 26. PEREZ-ACHARD, L.; GARCIA-ARUST, E.; GALEANO-MUÑOZ, C. - Metrazol activation in epilepsy. Electroencephalog. & Clin. Neurophysiol., 8:153-154, 1956.

[27] 27. PUPO, P. P.; ZUKERMAN, E. - Some comparative results of activation methods in electroencephalography. Electroencephalog. & Clin. Neurophysiol., 8:154, 1956.

[28] 28. RAS-MUSSEN, T.; JASPER, H. - Temporal lobe epilepsy: indication for operation and surgical technique. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.

[29] 29. SMITH, B.; FAZEKAS, J.; FORSTER, F. M.; SMITH, G. E. - Activation of the electroencephalogram with oral pentylenetetrazol. Proc. III Internat. Congress EEG Clin. Neurophysiol., Cambridge (Mass.), 1953.

[30] 30. STEVENS, J. R. - The "march" of temporal lobe epilepsy. Arch. Neurol. & Psychiat., 77:227-236, 1957.

[31] 31. STROBOS, R. J. - Mechanims in temporal lobe seizures. Arch. Neurol., 5:36-45, 1961.

[32] 32. TOWER, D. B. - The evidence for a neurochemical basis of seizures. In Temporal Lobe Epilepsy, edit, por M. Baldwin e P. Bailey. Charles C. Thomas, Springfield (Illinois), 1958.

[33] 33. VICTOR, M.; ANGEVINE, V.; MANCALL, E. L.; FISHER, C. M. - Memoryloss with lesions of hipocampal formation. Arch. Neurol., 5:244-263, 1961.

[34] 34. von MEDUNA, L. - Versuche über die biologische Beeinflussung des Ablaufes der Schizophrenia: Campher- und cardiazol Krampfe. Ztschr. Ges. Neurol, u. Psychiat., 152: 235, 1935.

[35] 35. WALKER, A. E. - Post-traumatic Epilepsy. Charles C. Thomas, Springfield (Illinois), 1949.

[36] 36. WEIL, A. A. - Ietal emotions occurring in temporal lobe dysfunction. Arch. Neurol., 1:87-97, 1959.