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Degeneração hepatolenticular: conteúdos de ferro e cobre em tecidos de material de autópsia

Hepatolenticular degeneration: iron and copper contents of tissues of autopsy material

Resumos

Os autores apresentam os resultados das dosagens de ferro e cobre nos tecidos de um paciente com degeneração hepatolenticular, no qual a moléstia teve curso fulminante. Parece que o curso da moléstia foi agravado pela administração de drogas tranqüilizantes quando foi iniciado o tratamento com penicilamina. Esta observação pode ser de interesse clínico. Os teores de cobre e ferro estavam muito aumentados nos tecidos cerebrais, no fígado, nos pulmões, nos rins, no baço, na suprarenal e em outros órgãos.


Iron and copper contents in tissues of one patient with hepatolenticular degeneration, with fulminating course, are reported. It seems that the disease's course was aggravated by tranquilizer drugs, when treatment with penicillamine was started. This observation may be of clinical interest. Copper and iron contents were increased in the brain tissues, in the liver, lungs, kidneys, spleen, suprarenal gland and in other organs.


Hepatolenticular degeneration: iron and copper contents of tissues of autopsy material

Degeneração hepatolenticular: conteúdos de ferro e cobre em tecidos de material de autópsia

Francisco Bastos De JorgeI; Luiz C. Gagliardi-FerreiraII; Charles Peter TilberyII

IDepartment of Medicine, Laboratory of Hormones, Escola Paulista de Medicina (Prof. Luciano Decourt)

IIDepartment of Medicine, Section of Neurology, Faculdade de Ciências Médicas da Santa Casa de São Paulo (Prof. O. Lemmi)

SUMMARY

Iron and copper contents in tissues of one patient with hepatolenticular degeneration, with fulminating course, are reported. It seems that the disease's course was aggravated by tranquilizer drugs, when treatment with penicillamine was started. This observation may be of clinical interest. Copper and iron contents were increased in the brain tissues, in the liver, lungs, kidneys, spleen, suprarenal gland and in other organs.

RESUMO

Os autores apresentam os resultados das dosagens de ferro e cobre nos tecidos de um paciente com degeneração hepatolenticular, no qual a moléstia teve curso fulminante. Parece que o curso da moléstia foi agravado pela administração de drogas tranqüilizantes quando foi iniciado o tratamento com penicilamina. Esta observação pode ser de interesse clínico. Os teores de cobre e ferro estavam muito aumentados nos tecidos cerebrais, no fígado, nos pulmões, nos rins, no baço, na suprarenal e em outros órgãos.

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Datas de Publicação

  • Publicação nesta coleção
    23 Abr 2013
  • Data do Fascículo
    Mar 1970
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