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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.31 no.4 São Paulo Dec. 1973

http://dx.doi.org/10.1590/S0004-282X1973000400006 

Índices para estimar o tempo transcorrido entre o surto hemorrágico subaracnóideo e a colheita de líquido cefalorraqueano

 

Appraisement of the time elapsed between cerebro-vascular accidents and cerebrospinal fluid examination. An experimental study

 

 

José M. Marlet

Faculdade de Medicina da Universidade de São Paulo: Professor Titular de Medicina Preventiva na Faculdade de Medicina de Catanduva e Professor Assistente na Faculdade de Medicina da Universidade de São Paulo

 

 


RESUMO

O autor simulou, experimentalmente, acidente vascular cerebral hemorrágico em cães injetando sangue do próprio animal no espaço subaracnóideo, colhendo amostras diárias de LCR durante 14 dias, sendo estudada a evolução das concentrações de oxiemoglobina e de bilirrubina, empregando métodos espectrofotométricos. Define um coeficiente hemoglobínico como a relação entre a concentração de oxiemoglobina e o total de pigmentos do LCR e um índice hemoglobina-bilirrubina como a relação entre as concentrações de oxiemoglobina e bilirrubina. Depois do tratamento estatístico, chega à conclusão de que ambos permitem estimar o tempo transcorrido desde o surto hemorrágico subaracnóideo e a colheita de LCR. São apresentadas sugestões quanto à aplicabilidade prática destes indicadores em Neurologia e Medicina Preventiva.


SUMMARY

Hemorrhagic cerebro-vascular accidents were simulated in dogs by injecting their own blood in the subarachnoidal space. Gathering daily samples of cerebrospinal fluid during 14 days the evolution of the concentrations of oxyhemoglobin and bilirubin using the spectrosphotometric method was studied. The author defines hemoglobin coefficient as being the relatinship between the oxyhemoglobin concentration and the sum of the cerebrospinal fluid pigments and the hemoglobin-bilirubin index as the relationship between the oxyhemoglobin and the bilirubin concentration. After statistical treatment the author concludes that both permit to calculate the time span between the subarachnoidal hemorrhage and the examination of the cerebrospinal fluid. Some suggestions on the practical applicability of these indexes in Clinical Neurology and Preventive Medicine are discussed.


 

 

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REFERÊNCIAS

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Departamento de Medicina Preventiva — Faculdade de Medicina da Universidade de São Paulo — Av. Dr. Arnaldo 455 — São Paulo — Brasil.

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