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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.33 no.1 São Paulo Mar. 1975

http://dx.doi.org/10.1590/S0004-282X1975000100002 

Studies of the thyroid function in children with Down's syndrome

 

Estudos da função tireóidea em crianças com síndrome de Down

 

 

Benjamin J. SchmidtI; Nelson CarvalhoII; Cláudio C. OrtegaIII; José LibermamIII; Jane M. M. BiazziIII; Pojucan M. TapajósIII; Stanislau KrynskiIV

IProfessor Adjunto do Departamento de Pediatria da EPM (Serviço Prof. A. A. Carvalho)
IIDiretor Clínico do Centro de Medicina Nuclear da FMUSP
IIIMédicos do Centro de Habilitação de São Paulo
IVDiretor Técnico do Centro de Habilitação de São Paulo

 

 


SUMMARY

The thyroid function (T-3 triiodothyronine; T-4 tetraiodothyronine and the captation of the I131 through the thyroid, in 2 and 24 hours after the intake of isotope radium), was studied in patients with Down's syndrome and the results being compared to those obtained from the respective siblings, all clinically normal. The comparative results showed no significant differences, except in the 2 hours captation of the I131 through the thyroid (P < 0.01). The findings suggest that the hypothalamus-hypophysary or the response of the thyroid gland would be slow, but compensated when analyzed after 24 hours.


RESUMO

Os autores estudaram a função tireóidea (T-3, triiodotironina; T-4, tetraiodotironina e captação do I131 pela tireóide com 2 e 24 horas após a ingestão do radioisótopo) em pacientes com síndrome de Down, e compararam os resultados com os obtidos nos seus respectivos irmãos, todos clinicamente normais. Os resultados comparativos não apresentaram diferenças significativas, exceto na captação de 2 horas do I131 pela tireóide (P < 0,01). Os achados sugerem que o estímulo hipotálamo hipofisário ou a resposta da glândula tireóide seria lento (a) mas compensado (a) quando analisados após 24 horas.


 

 

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REFERENCES

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Departamento de Pediatria — Escola Paulista de Melicina — Rua Botucatu 720 — 04203 São Paulo, SP — Brasil.
Trabalho apresentado no XVIII Congresso Brasileiro de Pediatria (Salvador, BA, de 13-10-1973), realizado no Centro de Habilitação de São Paulo, em colaboração com a Escola Paulista de Medicina (EPM) e o Centro de Medicina Nuclear da Faculdade de Medicina da Universidade de São Paulo (FMUSP), sob auxílio da Comissão Nacional de Energia Nuclear (São Paulo)

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