Carcinoma de plexo coroideo: relato de um caso

Japp, Hans H.; Farage Filho, Miguel

doi:10.1590/S0004-282X1976000300009

Resumos

É relatado um caso de carcinoma de plexo coróideo em paciente com 3 anos de idade, com hipertensão intracraniana. Sem um claro diagnóstico clínico, o paciente evoluiu para o óbito, em 8 dias. O exame neuropatológico do cérebro e estudo histopatológico do tecido removido, revelou um tumor maligno do plexo coróideo, de extrema raridade no sistema nervoso central.

The case of a three-years-old male with intracranial hypertension is reported. Without a clear clinical diagnosis, a gradual deterioration ocurred before his death, 8 days later. The neuropathological examination of the brain revealed a tumor with indistint borders at the right lateral ventricle, with granulous surface, pink-gray colour, irregular necrotic and hemorragic areas, invading the adjacent brain tissue. The histopathological study revealed a malignant variant of the choroid plexus tumor, of extreme rarity in the central nervous system. The biological and histological criteria accepted by Lewis, Rubinstein and Polak for the correct diagnosis of this type of tumour are discussed.

Carcinoma de plexo coroideo. Relato de um caso

Carcinoma of the choroid plexus: a case report

Hans H. Japp^I; Miguel Farage Filho^II

^IUnidade de Anatomia Patológica do 1.° Hospital Distrital de Brasília: Patologista e Diretor do Centro de Tumores do Sistema Nervoso

^IIUnidade de Anatomia Patológica do 1.° Hospital Distrital de Brasília: Neurocirurgião

RESUMO

É relatado um caso de carcinoma de plexo coróideo em paciente com 3 anos de idade, com hipertensão intracraniana. Sem um claro diagnóstico clínico, o paciente evoluiu para o óbito, em 8 dias. O exame neuropatológico do cérebro e estudo histopatológico do tecido removido, revelou um tumor maligno do plexo coróideo, de extrema raridade no sistema nervoso central.

SUMMARY

The case of a three-years-old male with intracranial hypertension is reported. Without a clear clinical diagnosis, a gradual deterioration ocurred before his death, 8 days later. The neuropathological examination of the brain revealed a tumor with indistint borders at the right lateral ventricle, with granulous surface, pink-gray colour, irregular necrotic and hemorragic areas, invading the adjacent brain tissue. The histopathological study revealed a malignant variant of the choroid plexus tumor, of extreme rarity in the central nervous system. The biological and histological criteria accepted by Lewis, Rubinstein and Polak for the correct diagnosis of this type of tumour are discussed.

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Unidade de Anatomia Patológica 1.° Hospital Distrital 70000 Brasília, DF Brasil.

Nota dos autores Agradecemos ao Prof. Moisés Polak a confirmação diagnóstica do presente caso.

1. DEL RIO HORTEGA, P. Estrutura e sistematización de los gliomas e paragliomas. Arch. Esp. Onc. 2:411, 1932.
2. DEL RIO HORTEGA, P. Anatomia microscopica de los tumores del sistema nervioso central y periferico. Actas del Primer Cong. Int. de Cancer, Madrid, 1933.
3. DASTUR, D. K. The broad field of neuropathology. Neurology (India) 15:51, 1967.
4. HOYTEMA, G. J. VAN & WINCKEL, W. E. F. Zur Frage des primären Plexuskarzinoms. Zbl. Neurochir. 17:353, 1957.
5. ITO, T. Pathology of the brain tumors. Acta Pathol. Jap. 8:415, 1958.
6. KERNOHAN, J. W. & SAYRE, G. P. Tumors of the Central Nervous System. Atlas of Tumor Pathology. Sec. X Fasc. 35-37, Armed Forces Institute of Pathology, Washington D.C., 1952.
7. WOSS, W. Th. & MILLER, M. H. Intracranial Tumors of Infants and Children. George Thieme Verlag, Stuttgart, 1971.
8. LEWIS, P. Carcinoma of the choroid plexus. Brain 90:177, 1967.
9. POLAK, M. Blastomas del Sistema Nervioso Central e Periferico. Lopes Libreros Editores, Buenos Aires, 1966.
10. POLAK, M.; SANCHEZ, J. S.; GOLONBEK, M. & HERREO, L. Consideraciones acerca de la llamada membrana basal. Arch. Fund. Roux-Ocefa 5:67, 1971.
11. ROUSSY, G. & OBERLING, C. Histologic classification of tumors of the central nervous system. Arch. Neurol. Psychiat. (Chicago) 27:1281, 1932.
12. RUSSEL, D. S. & RUBINSTEIN, L. J. Pathology of Tumours of the Nervous System. Third edition. Edward Arnolds Ltd., London, 1971.
13. RUBINSTEIN, L. J. Tumors of the Central Nervous System. Atlas of Tumor Pathology, Sec. Series. Fasc. 6. Armed Forces Institute of Pathology, Washington D.C., 1972.
14. ZIMMERMAN, H. M. Introduction to Tumors of the Central Nervous System. In Jeff Minckler, ed. Pathology of the Nervous System, Vol. II. McGraw-Hill Book Co., New York, 1971, p. 1947.
15. ZÜLCH, K. J. Brain Tumors: Their Biology and Pathology. Springer Publishing Co., New York, 1957.

Datas de Publicação

Publicação nesta coleção
26 Fev 2013
Data do Fascículo
Set 1976

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. DEL RIO HORTEGA, P. Estrutura e sistematización de los gliomas e paragliomas. Arch. Esp. Onc. 2:411, 1932.

[2] 2. DEL RIO HORTEGA, P. Anatomia microscopica de los tumores del sistema nervioso central y periferico. Actas del Primer Cong. Int. de Cancer, Madrid, 1933.

[3] 3. DASTUR, D. K. The broad field of neuropathology. Neurology (India) 15:51, 1967.

[4] 4. HOYTEMA, G. J. VAN & WINCKEL, W. E. F. Zur Frage des primären Plexuskarzinoms. Zbl. Neurochir. 17:353, 1957.

[5] 5. ITO, T. Pathology of the brain tumors. Acta Pathol. Jap. 8:415, 1958.

[6] 6. KERNOHAN, J. W. & SAYRE, G. P. Tumors of the Central Nervous System. Atlas of Tumor Pathology. Sec. X Fasc. 35-37, Armed Forces Institute of Pathology, Washington D.C., 1952.

[7] 7. WOSS, W. Th. & MILLER, M. H. Intracranial Tumors of Infants and Children. George Thieme Verlag, Stuttgart, 1971.

[8] 8. LEWIS, P. Carcinoma of the choroid plexus. Brain 90:177, 1967.

[9] 9. POLAK, M. Blastomas del Sistema Nervioso Central e Periferico. Lopes Libreros Editores, Buenos Aires, 1966.

[10] 10. POLAK, M.; SANCHEZ, J. S.; GOLONBEK, M. & HERREO, L. Consideraciones acerca de la llamada membrana basal. Arch. Fund. Roux-Ocefa 5:67, 1971.

[11] 11. ROUSSY, G. & OBERLING, C. Histologic classification of tumors of the central nervous system. Arch. Neurol. Psychiat. (Chicago) 27:1281, 1932.

[12] 12. RUSSEL, D. S. & RUBINSTEIN, L. J. Pathology of Tumours of the Nervous System. Third edition. Edward Arnolds Ltd., London, 1971.

[13] 13. RUBINSTEIN, L. J. Tumors of the Central Nervous System. Atlas of Tumor Pathology, Sec. Series. Fasc. 6. Armed Forces Institute of Pathology, Washington D.C., 1972.

[14] 14. ZIMMERMAN, H. M. Introduction to Tumors of the Central Nervous System. In Jeff Minckler, ed. Pathology of the Nervous System, Vol. II. McGraw-Hill Book Co., New York, 1971, p. 1947.

[15] 15. ZÜLCH, K. J. Brain Tumors: Their Biology and Pathology. Springer Publishing Co., New York, 1957.