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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.39 no.3 São Paulo Sept. 1981

http://dx.doi.org/10.1590/S0004-282X1981000300009 

Calcificação de núcleos da base do cérebro: estudo anatomopatológico de 4 casos

 

Calcification of basal ganglia: a study of 4 autopsied cases

 

 

Aristides Cheto de QueirozI; Ana Maria Blanco MalbouissonII

IProfessor Assistente do Departamento de Anatomia Patológica e Medicina Legal da Universidade Federal da Bahia, Bolsista do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
IIResidente do Serviço de Anatomia Patológica do Hospital Prof. Edgard Santos, Bolsista do CNPq

 

 


RESUMO

O trabalho consta do estudo anatomopatológico de 4 casos de calcificação de núcleos da base do cérebro, entidade que está mais relacionada a distúrbio metabólico endócrino do tipo hipoparatireoidismo e pseudohipoparatireoidismo. O estudo mostra a associação da deposição cálcica nos núcleos da base com lesão calcificada do cerebelo (cortex e núcleo denteado) em 2 casos. Demonstra também a presença não só de cálcio mas também de ferro nas lesões e a distribuição de manguito perivascular, característica dos depósitos. A ausência de uma doença básica comum e a falta de qualquer distúrbio metabólico associado, permite caracterizar estes casos como sendo de natureza idiopática ou pelo menos de causa não determinada.


SUMMARY

The paper reports the pathological study of 4 autopsied cases of massive basal ganglia calcifications, an entity that although related to hypoparathyroidism or pseudohypoparathyroidism, some times can be considered as idiopathic. In our cases no metabolic disturb or any common related disease could be found in association. Interesting is to point out that the lesion is confined to the central nervous system, with no foci of calcification outside the brain. There is a characteristic perivascular distribuition of the deposits that, as demonstrated by histochemical study are composed by ron besides calcium.


 

 

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Trabalho realizado no Serviço de Anatomia Patológica do Hospital Prof. Edgard Santos, Salvador, Bahia.
Serviço de Anatomia Patológica - Hospital Prof. Edgard Santos - 40.000 Salvador, B A. - Brasil.

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