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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.39 no.4 São Paulo Dec. 1981

http://dx.doi.org/10.1590/S0004-282X1981000400010 

  

Emprego dos gangliosidos do cortex cerebral nas neuropatias perifericas

 

Brain gangliosides in the treatment of peripheral neuropathies

 

 

 

James Pitagoras De MattosI; Fernando Carlos Aleixo SepulvedaI; Lucia Fontenelle VillaçaII

IProfessor Assistente. Instituto de Neurologia Deolindo Couto da U.F.R.J. (Serviço do Prof. Bernardo Couto)
IIAuxiliar de Ensino. Instituto de Neurologia Deolindo Couto da U.F.R.J. (Serviço do Prof. Bernardo Couto)

 

 


 

RESUMO

Os autores registram a experiência pessoal com o emprego de gangliosídios do cortex cerebral nas neuropatias periféricas. O ensaio clínico e eletromiográfico revelou-se eficaz em 30 dos 40 casos tratados. Enfatizam os melhores resultados em casos de paralisias faciais periféricas.


SUMMARY

Personal experience with brain gangliosides in the treatment of peripheral neuropathies is reported. The clinical and electromyografic trials were efficacious in 30 of 40 treated cases. The authors emphasize their better results in peripheral facial palsy cases.


 

 

 

 

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

 

 

   

REFERENCIAS

1. BURTON, R. M. - Gangiosides and relates substances of isolated cerebral tissues examined in relation to tissue excitability. Biochem. J., 81, 72, 1961.         [ Links ]

2. CECCARELI, B.; APORTI, F. & PINESSO, M. - Effects of brain gangliosides on functional recovery in experimental regeneration and reinnervation. Adv. Exp. Med. Biol., vol. 71 ed. Parcellati Plenum Press, 1976.         [ Links ]

3. DRAGO, G. & CASETTI, P. - I gangliosidi cerebrali: struttura, funzione ed alterazioni anatomopatologiche. Osped. Ital. Chir., 22, 189, 1970.         [ Links ]

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8. MARANGOLO, M. & VENTURA, F. - Observazioni cliniche sull'uso dei gangliosidi nelle affezioni dei nervi periferici. Acta Neurológica 31:6, 1976.         [ Links ]

9. MELLANBY, J. & POPE, D. - The relationship between the action of tetanus toxin and its binding by membranes and gangliosides. In Satellite Meeting Intern., Soc. for Neurochemistry, Cartona, 28-31 August, 1975.         [ Links ]

10. NEGRIN, P. & FARDIN, P. - Influenza dei gangliosidi di corteccia cerebrale sull'evoluzione clinico-EMGrafica della parallel facciale a frigore. Min. Med. 67, 1976.         [ Links ]

11. RASTOGI, R. N.; PRICHARD, J. S. & LOWDEN, J. A. - Elevation of phosphorus levels in serum and decreased brair content of gangliosides in rats following neonatal asphyxia. Pediat. Res. 2:125, 1968.         [ Links ]

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Trabalho realizado no Instituto de Neurologia Deolindo Couto da U.F.R.J. (Serviço do Prof. Bernardo Couto).
Instituto de Neurologia Deolindo Couto da U.F.R.J. - An. Venceslau Braz 95 - 22290 Rio de Janeiro, RJ - Brasil.

 

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