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Sonolência excessiva diurna, apnéia do sono tipo central e distrofia miotônica

Excessive daytime sleepiness, central sleep apnea and myotonic dystrophy

Resumos

São relatados dois casos de distrofia miotônica acompanhada de sonolência excessiva diurna. A avaliação polissonográfica de noite inteira revelou grande número de apnéias do sono tipo central deflagrando despertares freqüentes. As apnéias dos tipos obstrutivo e misto ocorreram em níveis normais e não se constatou hipoxia. Houve diminuição da eficiência do sono e redução dos estágios 3, 4 e REM. A apnéia central e a sonolência diurna que acarreta representariam manifestações precoces do comprometimento do sistema nervoso central na distrofia miotônica.


Two cases of myotonic dystrophy with excessive daytime somnolence are described. All-night polysomnographic studies were performed revealing high number of central sleep apnea which triggered micro-arousals and awakenings leading to decrease of sleep efficiency as well as of stage 3, 4 and REM. Obstructive and mixed apneas were found in the normal range. Hipoxia was not present in both recordings. Central sleep apneas and its secondary excessive daytime sleepinesse may indicate early signs of the central nervous system impairment related to myotonic dystrophy, as a multi-organ disease.


Sonolência excessiva diurna, apnéia do sono tipo central e distrofia miotônica

Excessive daytime sleepiness, central sleep apnea and myotonic dystrophy

Rubens ReimãoI; Helio LemmiII; Tulio BertoriniIII

INeurologista. Department of Neurodiagnostics, Sleep Disorders Center, Baptist Memorial Hospital e da University of Tennessee, Memphis, Tennessee, E.U.A

IIClinical Professor of Neurology. Department of Neurodiagnostics, Sleep Disorders Center, Baptist Memorial Hospital e da University of Tennessee, Memphis, Tennessee, E.U.A

IIIAssociate Professor of Neurology. Department of Neurodiagnostics, Sleep Disorders Center, Baptist Memorial Hospital e da University of Tennessee, Memphis, Tennessee, E.U.A. Bolsa CAPES 3502/82-3

RESUMO

São relatados dois casos de distrofia miotônica acompanhada de sonolência excessiva diurna. A avaliação polissonográfica de noite inteira revelou grande número de apnéias do sono tipo central deflagrando despertares freqüentes. As apnéias dos tipos obstrutivo e misto ocorreram em níveis normais e não se constatou hipoxia. Houve diminuição da eficiência do sono e redução dos estágios 3, 4 e REM. A apnéia central e a sonolência diurna que acarreta representariam manifestações precoces do comprometimento do sistema nervoso central na distrofia miotônica.

SUMMARY

Two cases of myotonic dystrophy with excessive daytime somnolence are described. All-night polysomnographic studies were performed revealing high number of central sleep apnea which triggered micro-arousals and awakenings leading to decrease of sleep efficiency as well as of stage 3, 4 and REM. Obstructive and mixed apneas were found in the normal range. Hipoxia was not present in both recordings. Central sleep apneas and its secondary excessive daytime sleepinesse may indicate early signs of the central nervous system impairment related to myotonic dystrophy, as a multi-organ disease.

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Trabalho do Department of Neurodiagnostics, Sleep Disorders Center, Baptist Memorial Hospital e da University of Tennessee, Memphis, Tennessee, E.U.A.

Sleep Disorders Center, Department of Neurodiagnostics, Baptist Memorial Hospital - 899 Madison Avenue - Memphis, Tennessee, 38146 - U.S.A.

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Datas de Publicação

  • Publicação nesta coleção
    09 Ago 2012
  • Data do Fascículo
    Dez 1985
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