Disfunções neuropsicológicas na doença de Parkinson: estudo de 64 casos

 

Neuropsychologic dysfunctions in Parkinson's disease: a study of 64 cases

 

 

Egberto Reis Barbosa^I; Beatriz Helena Lefèvre^II; Luiz Roberto Comerlatti^I; Milberto Scaff^III; Horácio Martins Canelas^IV

^IMédico Assistente - Trabalho realizado na Divisão de Clínica Neurológica (Ambulatório de Moléstias Extrapiramidais) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
^IIPsicóloga - Trabalho realizado na Divisão de Clínica Neurológica (Ambulatório de Moléstias Extrapiramidais) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
^IIIProfessor Adjunto - Trabalho realizado na Divisão de Clínica Neurológica (Ambulatório de Moléstias Extrapiramidais) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
^IVProfessor Titular - Trabalho realizado na Divisão de Clínica Neurológica (Ambulatório de Moléstias Extrapiramidais) do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

 

 

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RESUMO

Foram estudados 64 casos de doença de Parkinson idiopática mediante aplicação de questionário de 30 itens de avaliação neuropsicológica. Os casos com desempenho abaixo do normal e que preenchiam os critérios de demência do Manual de Diagnóstico e Estatística de Distúrbios Mentais, terceira edição (DSM III) foram considerados demenciados. O resultado dessa avaliação mostrou que a taxa de prevalência de demência no grupo de parkinsonianos estudado foi de 18,7%. Pacientes com desempenho abaixo do normal apresentavam oligocinesia em maior grau que o grupo dos normais. Das funções neuropsicológicas, as mais afetadas foram: memória imediata, abstração, gnosia visual, cálculo, função motora dinâmica das mãos, praxia construtiva e memória recente. Discutem-se os dados encontrados e comparam-se com os da literatura.

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SUMMARY

Sixty-four cases of idiopathic Parkinson's disease were studied focusing the neuropsychological performance. To all subjects a brief mental status questionnaire was administered (30 items). Cases with a performance below normal and meeting the dementia criteria of the Diagnosis and Statistical Manual of Mental Disorders, third edition (DSM III), were considered demented. This evaluation showed that 12 of the 64 patients had dementia, a prevalence rate of 18.7%. Patients that had neuropsychological performance below normal showed more severe bradykinesia than normals. Short term memory, abstract thinking, visual gnosia, calculations, dynamic motor function of hands, constructional ability and recent memory were the most affected psychological functions. The significance of the mentioned findings is discussed and the literature reviewed.

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Full text available only in PDF format.

 

 

Agradecimentos - Agradecemos aos Drs. Sérgio Domingos Pitelli e Luís dos Ramos Machado pelo estudo estatístico, e a Marina San Martin Machado pelo trabalho datilográfico.

 

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