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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.45 no.3 São Paulo Sept. 1987

http://dx.doi.org/10.1590/S0004-282X1987000300005 

Eletrencefalograma antes e após hemodiálise, diálise peritoneal e transplante renal: estudo de correlações da atividade de fundo com a bioquímica plasmática

 

Electroencephalogram before and after hemodyalisis, peritoneal dialysis and renal transplant: study of correlations between background activity and plasmatic biochemistry

 

 

Luiz Antonio de Lima ResendeI; José Geraldo SpecialiII

IMestre em Neurologia - Trabalho realizado no Departamento de Neuropsiquiatria e Psicologia Médica da Faculdade de Medicina de Ribeirão Preto (FMRP) da Universidade de São Paulo
IIProfessor Livre-Docente - Trabalho realizado no Departamento de Neuropsiquiatria e Psicologia Médica da Faculdade de Medicina de Ribeirão Preto (FMRP) da Universidade de São Paulo

 

 


RESUMO

Estudamos as correlações entre atividade de fundo no EEG e anormalidades bioquímicas do plasma em 49 pacientes com insuficiência renal crônica. Foi realizado estudo do EEG e bioquímico antes e após hemodiálise em 20 pacientes, antes e após diálise peritoneal em 14 e antes e após transplante renal em 15 pacientes. Observamos piora do EEG após hemodiálise e diálise peritoneal e melhora do EEG após transplante, sugerindo que em nossos pacientes as alterações da atividade de fundo induzidas pela uremia crônica eram reversíveis. Com base em nossos resultados, consideramos difícil estabelecer correlações entre o EEG e alterações da bioquímica plasmática. Entretanto, há correlação estatística entre hipernatremia, melhora da acidose metabólica, aumento da relação zinco/cobre e piora da atividade de fundo no EEG.


SUMMARY

We report disorganization of background activity in the EEG of 49 patients with chronic renal failure. An electroencephalographic and biochemical study was performed in 20 patients before and after dialysis sessions. We did the same study before and after peritoneal dialysis in 14 patients. We analysed the EEG compared to biochemical blood abnormalities before and after renal transplantation in 15 patients. We observed worsening of the EEG after hemodialysis and peritoneal dialysis and improvement after renal transplantation, suggesting that in our patients the abnormalities in EEG caused by chronic renal failure were reversible. From our results, we found it difficult to establish correlations between the EEG and the biochemical blood abnormalities. However, there is statistical correlation between hipernatremia, improvement of metabolic acidosis, increase of the ratio of zinc to copper and worsening of the background activity in EEG.


 

 

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