Tuberculomas cerebrais múltiplos: relato de um caso autopsiado com 37 lesões

Pittella, José Eymard Homem; Toppa, Nivaldo Hartung

doi:10.1590/S0004-282X1988000200008

Resumos

É descrito caso autopsiado com 37 tuberculomas cerebrais, o de maior número de lesões descrito na literatura. O paciente era alcoólatra crônico e tinha tuberculose generalizada. Faz-se revisão da literatura de tuberculomas cerebrais múltiplos e comenta-se o quadro clínico neurológico apresentado pelo paciente e a associação entre tuberculose generalizada e alcoolismo crônico.

An autopsied case of multiple cerebral tuberculomas with 37 lesions, the one with the greatest number of lesions described in the literature, is reported. The patient was a chronic alcoholic and had generalized tuberculosis. The literature on multiple cerebral tuberculomas is reviewed and the neurological clinical picture presented by the patient and the association between generalized tuberculosis and chronic alcoholism arc commented upon.

José Eymard Homem Pittella; Nivaldo Hartung Toppa

Laboratório de Neuropatologia, Departamento de Anatomia Patológica e Medicina Legal, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG)

RESUMO

É descrito caso autopsiado com 37 tuberculomas cerebrais, o de maior número de lesões descrito na literatura. O paciente era alcoólatra crônico e tinha tuberculose generalizada. Faz-se revisão da literatura de tuberculomas cerebrais múltiplos e comenta-se o quadro clínico neurológico apresentado pelo paciente e a associação entre tuberculose generalizada e alcoolismo crônico.

SUMMARY

An autopsied case of multiple cerebral tuberculomas with 37 lesions, the one with the greatest number of lesions described in the literature, is reported. The patient was a chronic alcoholic and had generalized tuberculosis. The literature on multiple cerebral tuberculomas is reviewed and the neurological clinical picture presented by the patient and the association between generalized tuberculosis and chronic alcoholism arc commented upon.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Departamento de Anatomia Patológica e Medicima Legal, Faculdade de Medicina, UFMG - Av. Alfredo Balena 190 - 30130 Belo Horizonte MG - Brasil.

1. Adams HG, Jordan C - Infections in the alcoholic. Med Clin North Am 68: 179, l984.
2. Ali MV, Nolan JP - Alcohol induced depression of reticuloendothelial function in the rat. J Lab Clin Med 70: 295, 1967.
3. Anderson JM, MacMillan JJ - Intracranial tuberculoma: as increasing problem in Britain. J Neurol Neurosurg Psychiat 38: 194, 1975.
4. Arseni C - Two hundred and one cases of intracranial tuberculoma treated surgically. J Neurol Neurosurg Psychiat 21: 308, 1958.
5. Asenjo A, Valladares H, Fierro J - Tuberculomas of the brain: report of one hundred and fifty-nine cases. Arch Neurol Psychiat 65: 146, 1951.
6. Bagchi A - The intracranial tuberculomas. J Ind Med Assoc 37: 429, 1961.
7. Balaparameswararao MS, Dinakar I - Tuberculomas of the, brain. Int Surg 57: 216, 1972.
8. Barbosa LML, Teixeira LC - Tuberculomas cerebrais múltiplos em lactente. Arq Neuro-Psiquiat (São Paulo) 30: 72, 1972.
9. Berlin L - Tuberculoma of the brain. Am J Roentgen 90: 1185, 1963.
10. Bijorkholm M - Immunological and hematological abnormalities in chronic alcoholism. Acta Med Scand 207: 197, 1980.
11. Brayton RG, Stokes PE, Schwartz MS, Louria DB - Effect of alcohol and various diseases on leukocyte mobilization, phagocytosis and intracellular bacterial killing. N Engl J Med 282: 123, 1970.
12. Castro M, Lepe A - Cerebral tuberculoma. Acta Radiol 1: 821, 1963.
13. Conn HO - A rational program for the management of hepatic coma. Gastroenterology 57: 715, 1969.
14. Dastur HM, Desai AD - A comparative study of brain tuberculomas and gliomas based upon 107 cases records of each. Brain 88: 375, 1965.
15. Dastur DK, Lalitha VS - The many facets of neurotuberculosis: an epitome of neuropathology. In Progress in Neuropathology, Vol. 2. Grune & Stratton, New York, 1973.
16. Dastur DK, Lalitha VS, Prabhakar V - Pathological analysis of intracranial space-occupying lesions in 1000 cases including children. Part 1: age, sex and pattern; and the tuberculomas. J Neurol Sci 6: 575, 1968.
17. Dimitri V - Algunos aspectos de la tuberculosis del encefalo. Rev Arg Tuberc 3: 367, 1937.
18. Garland HG, Armitage G - Intracranial tuberculoma. J Path Bact 37: 461, 1933.
19. Gluckman SJ, Dvorak VC, MacGregor RR - Host defenses during prolonged alcohol consumption in a controled environment. Arch Intern Med 137: 1539, 1977.
20. Gonzalez-Revilla A - Intracranial tuberculomas: experience with ten consecutive cases. J Neurosurg 9: 555, 1952.
21. Grant FC - A study of the results of surgical treatment in 2326 consecutive patients with brain tumour. J Neurosurg 13: 475, 1956.
22. Guarnieri JJ, Laurenzi GA - Effect of alcohol on the mobilization of alveolar macrophages. J Lab Clin Med 72: 40, 1968.
23. Harder E, Al-Kawi MZ, Carney P - Intracranial tuberculoma: conservative management. Am J Med 74: 570, 1983.
24. Harriman DGF - Bacterial infections of the central nervous system. In Greenfield's Neuropathology. Ed. 4. Edward Arnold, London, 1984.
25. Lana-Peixoto MA, Pittella JEH, Bambirra EA, Arouca EMG - Tuberculomas intracranianos: estudo clínico e patológico. Arq Neuro-Psiquiat (São Paulo) 40: 117, 1982.
26. Lees AJ, Marshall J, MacLeod AF - Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet 1: 1208, 1980.
27. Levy LF, Axton J - Neurosurgery in Rhodesia. In Spillane JD (ed): Tropical Neurology. Oxford Univ Press, London, 1973.
28. Liu YK - Phagocytic capacity of reticuloendothelial system in alcoholics. J Reticuloendothel Soc 25: 605, 1979.
29. Loizou LA, Anderson M - Intracranial tuberculomas: correlation of computerized tomography with clinicopathological findings. Quart J Med 51: 104, 1982.
30. MacGregor RR, Gluckman JR Senior - Granulocyte function and levels of immunoglobulins and complement in patients admitted for withdrawal from alcohol. J Infect Dis 138: 747, 1978.
31. Mocquard Y, Chevalier F, Borsotti JP, Goas JY, Le. Guyader J - Tubereulcmes multiples intra-cérébraux: diagnostic et contrôles tomodensitométriques de l'évolution: un cas. Ann Med Interne 136: 405, 1985.
32. Morland B, Morland J - Effects of long term ethanol consumption on rat peritoneal macrophages. Acta Pharmacol Toxicol 50: 221, 1982.
33. Odeku EL, Adeloye A - Cerebral tuberculomas in nigérian patients. Trop Geograph Med 21: 293, 1969.
34. Olivecrona H - The surgical treatment of intracranial tumors. In Handbuch der Neurochirurgie, Vol. 4, Part 4. Springer, Berlin, 1967.
35. Rasdolsky I - Tuberkulome des Gehirnes. Z ges Neurol Psychiatr 154: 18, 1935.
36. Scheidegger S - Tuberkulose. In Handbuch der speziellen pathologischen Anatomie und Histologie: dreizehnter Band, zweiter Teil, Bandteil A. Springer, Berlin, 1958.
37. Sibley WA, O'Brien JL - Intracranial tuberculomas: a review of clinical features and treatment. Neurology 6: 157, 1956.
38. Tennembraum JI, Ruppert RD, St Pierre RL, Greenberger NJ - The effect of chronic alcohol administration on the immune responsiveness of rats. J Allergy 44: 272, 1969.
39. Thrush DC, Barwick DD - Theree patients with intracranial tuberculomas with unusual features. J Neurol Neurosurg Psychiat 37: 566, 1974.
40. Tyler B, Bennett H, Kim J - Intracranial tuberculomas in a child: computed tomographic scan diagnosis and nonsurgical management. Pediatrics 71: 952, 1983.
41. Zülch KJ - Biologie und Pathologie der Hirngeschwülste. In Handbuch der Neurochirurgie, Vol. 3. Springer, Berlin, 1956.

Tuberculomas cerebrais múltiplos: relato de um caso autopsiado com 37 lesões

Multiple cerebral tuberculomas: report of a post-mortem examined case with 37 lesions

Datas de Publicação

Publicação nesta coleção
21 Jun 2011
Data do Fascículo
Jun 1988

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Adams HG, Jordan C - Infections in the alcoholic. Med Clin North Am 68: 179, l984.

[2] 2. Ali MV, Nolan JP - Alcohol induced depression of reticuloendothelial function in the rat. J Lab Clin Med 70: 295, 1967.

[3] 3. Anderson JM, MacMillan JJ - Intracranial tuberculoma: as increasing problem in Britain. J Neurol Neurosurg Psychiat 38: 194, 1975.

[4] 4. Arseni C - Two hundred and one cases of intracranial tuberculoma treated surgically. J Neurol Neurosurg Psychiat 21: 308, 1958.

[5] 5. Asenjo A, Valladares H, Fierro J - Tuberculomas of the brain: report of one hundred and fifty-nine cases. Arch Neurol Psychiat 65: 146, 1951.

[6] 6. Bagchi A - The intracranial tuberculomas. J Ind Med Assoc 37: 429, 1961.

[7] 7. Balaparameswararao MS, Dinakar I - Tuberculomas of the, brain. Int Surg 57: 216, 1972.

[8] 8. Barbosa LML, Teixeira LC - Tuberculomas cerebrais múltiplos em lactente. Arq Neuro-Psiquiat (São Paulo) 30: 72, 1972.

[9] 9. Berlin L - Tuberculoma of the brain. Am J Roentgen 90: 1185, 1963.

[10] 10. Bijorkholm M - Immunological and hematological abnormalities in chronic alcoholism. Acta Med Scand 207: 197, 1980.

[11] 11. Brayton RG, Stokes PE, Schwartz MS, Louria DB - Effect of alcohol and various diseases on leukocyte mobilization, phagocytosis and intracellular bacterial killing. N Engl J Med 282: 123, 1970.

[12] 12. Castro M, Lepe A - Cerebral tuberculoma. Acta Radiol 1: 821, 1963.

[13] 13. Conn HO - A rational program for the management of hepatic coma. Gastroenterology 57: 715, 1969.

[14] 14. Dastur HM, Desai AD - A comparative study of brain tuberculomas and gliomas based upon 107 cases records of each. Brain 88: 375, 1965.

[15] 15. Dastur DK, Lalitha VS - The many facets of neurotuberculosis: an epitome of neuropathology. In Progress in Neuropathology, Vol. 2. Grune & Stratton, New York, 1973.

[16] 16. Dastur DK, Lalitha VS, Prabhakar V - Pathological analysis of intracranial space-occupying lesions in 1000 cases including children. Part 1: age, sex and pattern; and the tuberculomas. J Neurol Sci 6: 575, 1968.

[17] 17. Dimitri V - Algunos aspectos de la tuberculosis del encefalo. Rev Arg Tuberc 3: 367, 1937.

[18] 18. Garland HG, Armitage G - Intracranial tuberculoma. J Path Bact 37: 461, 1933.

[19] 19. Gluckman SJ, Dvorak VC, MacGregor RR - Host defenses during prolonged alcohol consumption in a controled environment. Arch Intern Med 137: 1539, 1977.

[20] 20. Gonzalez-Revilla A - Intracranial tuberculomas: experience with ten consecutive cases. J Neurosurg 9: 555, 1952.

[21] 21. Grant FC - A study of the results of surgical treatment in 2326 consecutive patients with brain tumour. J Neurosurg 13: 475, 1956.

[22] 22. Guarnieri JJ, Laurenzi GA - Effect of alcohol on the mobilization of alveolar macrophages. J Lab Clin Med 72: 40, 1968.

[23] 23. Harder E, Al-Kawi MZ, Carney P - Intracranial tuberculoma: conservative management. Am J Med 74: 570, 1983.

[24] 24. Harriman DGF - Bacterial infections of the central nervous system. In Greenfield's Neuropathology. Ed. 4. Edward Arnold, London, 1984.

[25] 25. Lana-Peixoto MA, Pittella JEH, Bambirra EA, Arouca EMG - Tuberculomas intracranianos: estudo clínico e patológico. Arq Neuro-Psiquiat (São Paulo) 40: 117, 1982.

[26] 26. Lees AJ, Marshall J, MacLeod AF - Cerebral tuberculomas developing during treatment of tuberculous meningitis. Lancet 1: 1208, 1980.

[27] 27. Levy LF, Axton J - Neurosurgery in Rhodesia. In Spillane JD (ed): Tropical Neurology. Oxford Univ Press, London, 1973.

[28] 28. Liu YK - Phagocytic capacity of reticuloendothelial system in alcoholics. J Reticuloendothel Soc 25: 605, 1979.

[29] 29. Loizou LA, Anderson M - Intracranial tuberculomas: correlation of computerized tomography with clinicopathological findings. Quart J Med 51: 104, 1982.

[30] 30. MacGregor RR, Gluckman JR Senior - Granulocyte function and levels of immunoglobulins and complement in patients admitted for withdrawal from alcohol. J Infect Dis 138: 747, 1978.

[31] 31. Mocquard Y, Chevalier F, Borsotti JP, Goas JY, Le. Guyader J - Tubereulcmes multiples intra-cérébraux: diagnostic et contrôles tomodensitométriques de l'évolution: un cas. Ann Med Interne 136: 405, 1985.

[32] 32. Morland B, Morland J - Effects of long term ethanol consumption on rat peritoneal macrophages. Acta Pharmacol Toxicol 50: 221, 1982.

[33] 33. Odeku EL, Adeloye A - Cerebral tuberculomas in nigérian patients. Trop Geograph Med 21: 293, 1969.

[34] 34. Olivecrona H - The surgical treatment of intracranial tumors. In Handbuch der Neurochirurgie, Vol. 4, Part 4. Springer, Berlin, 1967.

[35] 35. Rasdolsky I - Tuberkulome des Gehirnes. Z ges Neurol Psychiatr 154: 18, 1935.

[36] 36. Scheidegger S - Tuberkulose. In Handbuch der speziellen pathologischen Anatomie und Histologie: dreizehnter Band, zweiter Teil, Bandteil A. Springer, Berlin, 1958.

[37] 37. Sibley WA, O'Brien JL - Intracranial tuberculomas: a review of clinical features and treatment. Neurology 6: 157, 1956.

[38] 38. Tennembraum JI, Ruppert RD, St Pierre RL, Greenberger NJ - The effect of chronic alcohol administration on the immune responsiveness of rats. J Allergy 44: 272, 1969.

[39] 39. Thrush DC, Barwick DD - Theree patients with intracranial tuberculomas with unusual features. J Neurol Neurosurg Psychiat 37: 566, 1974.

[40] 40. Tyler B, Bennett H, Kim J - Intracranial tuberculomas in a child: computed tomographic scan diagnosis and nonsurgical management. Pediatrics 71: 952, 1983.

[41] 41. Zülch KJ - Biologie und Pathologie der Hirngeschwülste. In Handbuch der Neurochirurgie, Vol. 3. Springer, Berlin, 1956.