Displasia fibrosa do osso temporal e vasculopatia oclusiva cerebral relato de caso

Inamorato, Elaine; Nogueira, Roberto Gomes; Minatti-Hannuch, Susanmeire N.; Zukerman, Eliova

doi:10.1590/S0004-282X1992000200018

Resumos

Displasia fibrosa é doença óssea benigna de etiologia desconhecida. O envolvimento craniofacial pode causar distúrbios neurológicos. O diagnóstico é feito pelo aspecto radiográfico. É apresentado uni caso de associação entre quadro clínico de displasia fibrosa, com envolvimento do nervo facial, infartos cerebrais e título elevado de anticorpo anticar-diolipina. A angiografia mostrou oclusões de várias artérias cerebrais. O exame pós-morte revelou infarto recente do miocárdio, amolecimento cerebral isquêmico e arteriosclerose generalizada.

displasia fibrosa; trombose cerebral; anticorpo anticardiolipina

Fibrous dysplasia is a benign disease with unknown etiology. Skull attempt may cause neurological disorders. The diagnostic can be made through radiological examination. A case of a patient with right temporal bone involvement with facial palsy, right parietal lobe infarctions and elevated anticardiolipin antibody titers is presented. Cerebral angiography showed occlusion of several cerebral arteries. Post mortem examination displayed recent myocardial infarction, ischemic cerebral softening, and generalized arteriosclerosis. The simultaneous occurrence of fibrous dysplasia and a probable anticardiolipin syndrome is commented.

fibrous dysplasia; cerebral thrombosis; anticardiolipin antibody

Displasia fibrosa do osso temporal e vasculopatia oclusiva cerebral relato de caso

Fibrous dysplasia of the temporal bone and cerebral occlusive vasculopathy: case report

Elaine Inamorato^I; Roberto Gomes Nogueira^II; Susanmeire N. Minatti-Hannuch^III; Eliova Zukerman^IV

^IPós-graduanda. Setor de Investigação e Tratamento das Cefaléias (SITC) do Departamento de Neurologia e Neurocirurgia e Departamento de Diagnóstico por Imagem da Escola Paulista de Medicina

^IIProfessor Assistente de Neurorradiologia. Setor de Investigação e Tratamento das Cefaléias (SITC) do Departamento de Neurologia e Neurocirurgia e Departamento de Diagnóstico por Imagem da Escola Paulista de Medicina

^IIIDoutor em Medicina e Médica Assistente. Setor de Investigação e Tratamento das Cefaléias (SITC) do Departamento de Neurologia e Neurocirurgia e Departamento de Diagnóstico por Imagem da Escola Paulista de Medicina

^IVProfessor Adjunto e Chefe do SITC. Setor de Investigação e Tratamento das Cefaléias (SITC) do Departamento de Neurologia e Neurocirurgia e Departamento de Diagnóstico por Imagem da Escola Paulista de Medicina

RESUMO

Displasia fibrosa é doença óssea benigna de etiologia desconhecida. O envolvimento craniofacial pode causar distúrbios neurológicos. O diagnóstico é feito pelo aspecto radiográfico. É apresentado uni caso de associação entre quadro clínico de displasia fibrosa, com envolvimento do nervo facial, infartos cerebrais e título elevado de anticorpo anticar-diolipina. A angiografia mostrou oclusões de várias artérias cerebrais. O exame pós-morte revelou infarto recente do miocárdio, amolecimento cerebral isquêmico e arteriosclerose generalizada.

Palavras-chave: displasia fibrosa, trombose cerebral, anticorpo anticardiolipina.

SUMMARY

Fibrous dysplasia is a benign disease with unknown etiology. Skull attempt may cause neurological disorders. The diagnostic can be made through radiological examination. A case of a patient with right temporal bone involvement with facial palsy, right parietal lobe infarctions and elevated anticardiolipin antibody titers is presented. Cerebral angiography showed occlusion of several cerebral arteries. Post mortem examination displayed recent myocardial infarction, ischemic cerebral softening, and generalized arteriosclerosis. The simultaneous occurrence of fibrous dysplasia and a probable anticardiolipin syndrome is commented.

Key words: fibrous dysplasia, cerebral thrombosis, anticardiolipin antibody.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Dr. Eliova Zukerman Disciplina de Neurologia, Escola Paulista de Medicima - Rua Botucatu 740 - 04023 São Paulo SP - Brasil.

1. Brey RL, Hart RG, Sherman DG, Tegeler CH. Antiphospholipid antibodies and cerebral ' isquemia in young people. Neurology 1990, 40:1190-1195.
2. Daffner RH, Kirko DR, Gehweiler JA Jr, Heaston DDK. Computed tomography of fibrous dysplasia. AJR 1982, 139:943-948.
3. Damao-Camara T, Clough JD. Anticardiolipin antibodies in systemic lupus eritematosus. Clev Clin J Med 1989, 56:525-528.
4. Freitas PE, Ribeiro TR, Coutinho MF, Anicet A. Displasia fibrosa do crânio: manifestações neurológicas. Arq Neuro-Psiquiat (São Paulo) 1989, 47:187-191.
5. Hamsten A, Bjorkholm M, Norberg R, Be Faire V, Holm G. Antibodies to cardiolipin in young survivors of myocardial infarction: an association with recurrent cardiovascular events. Lancet 1986, 2:113-115.
6. Hughes GRV. The anticardiolipin syndrome. J Rheumatol 1986, 13:486-489.
7. Levine SR, Deegan MJ, Futrell N, Welch KMA. Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 cases. Neuroüogy 1990, 40:1181-1189.
8. Levine SR, Kim S, Deegan MJ, Welch KMA. Ischemic stroke associated with anticardiolipin antibodies. Stroke 1987, 18:1101-1106.
9. Levine SR, Welch KMA. The spectrum of neurologic disease associated with anticardiolipin antibodies: lupus eritematosus anticoagulants and anticardiolipin antibodies. Arch Neurol 1987, 44:876-883.
10. Levine SR, Welch KMA. Antiphospholipid antibodies. Ann Neurol 1989, 26:386-389.
11. Lin JP, Goodkin R, Chase NE, Kricheff II. The angiographic features of fibrous dysplasia of skull. Radiology 1969, 92:1275-1280.
12. Mendelson DB, Hetzanu J, Cohen M, Tello G. Computed tomography of craniofacial fibrous dysplasia. J Comput Assist Tomogr 1984, 8:1062-1065.
13. Nager GT, Holliday MJ. Fibrous dysplasia of the temporal bone: Update with case reports. Ann Otol Rhinol Laryngol 1984, 93:630-633.
14. Nager GT, Kennedy DW, Kopstein E. Fibrous dysplasia: a review of the disease and manifestations in the temporal bone. Ann Otol Rhinol Laringol 1982, 91 (suppl 92):l-52.
15. Ramsey HE, Strong EW, Frazel EL. Fibrous dysplasia of the craniofacial bones. Am J Surg 1968, 116:542-547.
16. Younus M, Haleen A. Monostotic fibrous dysplasia of the temporal bone. J Laryngol Otol 1987, 101:1070-1074.

Datas de Publicação

Publicação nesta coleção
22 Fev 2011
Data do Fascículo
Jun 1992

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Brey RL, Hart RG, Sherman DG, Tegeler CH. Antiphospholipid antibodies and cerebral ' isquemia in young people. Neurology 1990, 40:1190-1195.

[2] 2. Daffner RH, Kirko DR, Gehweiler JA Jr, Heaston DDK. Computed tomography of fibrous dysplasia. AJR 1982, 139:943-948.

[3] 3. Damao-Camara T, Clough JD. Anticardiolipin antibodies in systemic lupus eritematosus. Clev Clin J Med 1989, 56:525-528.

[4] 4. Freitas PE, Ribeiro TR, Coutinho MF, Anicet A. Displasia fibrosa do crânio: manifestações neurológicas. Arq Neuro-Psiquiat (São Paulo) 1989, 47:187-191.

[5] 5. Hamsten A, Bjorkholm M, Norberg R, Be Faire V, Holm G. Antibodies to cardiolipin in young survivors of myocardial infarction: an association with recurrent cardiovascular events. Lancet 1986, 2:113-115.

[6] 6. Hughes GRV. The anticardiolipin syndrome. J Rheumatol 1986, 13:486-489.

[7] 7. Levine SR, Deegan MJ, Futrell N, Welch KMA. Cerebrovascular and neurologic disease associated with antiphospholipid antibodies: 48 cases. Neuroüogy 1990, 40:1181-1189.

[8] 8. Levine SR, Kim S, Deegan MJ, Welch KMA. Ischemic stroke associated with anticardiolipin antibodies. Stroke 1987, 18:1101-1106.

[9] 9. Levine SR, Welch KMA. The spectrum of neurologic disease associated with anticardiolipin antibodies: lupus eritematosus anticoagulants and anticardiolipin antibodies. Arch Neurol 1987, 44:876-883.

[10] 10. Levine SR, Welch KMA. Antiphospholipid antibodies. Ann Neurol 1989, 26:386-389.

[11] 11. Lin JP, Goodkin R, Chase NE, Kricheff II. The angiographic features of fibrous dysplasia of skull. Radiology 1969, 92:1275-1280.

[12] 12. Mendelson DB, Hetzanu J, Cohen M, Tello G. Computed tomography of craniofacial fibrous dysplasia. J Comput Assist Tomogr 1984, 8:1062-1065.

[13] 13. Nager GT, Holliday MJ. Fibrous dysplasia of the temporal bone: Update with case reports. Ann Otol Rhinol Laryngol 1984, 93:630-633.

[14] 14. Nager GT, Kennedy DW, Kopstein E. Fibrous dysplasia: a review of the disease and manifestations in the temporal bone. Ann Otol Rhinol Laringol 1982, 91 (suppl 92):l-52.

[15] 15. Ramsey HE, Strong EW, Frazel EL. Fibrous dysplasia of the craniofacial bones. Am J Surg 1968, 116:542-547.

[16] 16. Younus M, Haleen A. Monostotic fibrous dysplasia of the temporal bone. J Laryngol Otol 1987, 101:1070-1074.