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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.52 no.2 São Paulo June 1994

http://dx.doi.org/10.1590/S0004-282X1994000200005 

Tremor essencial: caracterização clínica de uma amostra de 176 pacientes

 

Essential tremor: clinical evaluation of 176 patients

 

 

Vanderci BorgesI; Henrique Ballalai FerrazII; Luiz Augusto Franco de AndradeIII

ISetor de Investigação de Moléstias Extrapiramidais do Departamento de Neurologia e Neurocirurgia da Escola Paulista de Medicina (EPM): Pós-Graduanda
IISetor de Investigação de Moléstias Extrapiramidais do Departamento de Neurologia e Neurocirurgia da Escola Paulista de Medicina (EPM): Médico Assistente-Doutor
IIISetor de Investigação de Moléstias Extrapiramidais do Departamento de Neurologia e Neurocirurgia da Escola Paulista de Medicina (EPM): Professor Adjunto

 

 


RESUMO

Revisamos os registros de 176 pacientes com tremor essencial (TE) quanto à história familiar, características do tremor, distribuição anatômica, idade de início dos sintomas. Os pacientes foram divididos em dois grupos: familiar (F) e não familiar (NF). História familiar de tremor foi encontrada em 47,2% da amostra. O tremor de ação e postura ocorreu combinadamente em 49,4%, somente de postura em 26,7% e somente de ação em 9,1%. O tremor de repouso foi registrado em 10,2%, sempre associado a outras características. Não houve diferenças clínicas entre os grupos Fe NF As mãos foram acometidas em 94,9% e a cabeça em 26,5%. O acometimento isolado das mãos foi mais frequente no sexo masculino, enquanto o tremor de cabeça foi mais frequente no sexo feminino. A idade de início variou de 4 a 85 anos e se mostrou significantemente menor nos pacientes do sexo masculino com história familiar (36,5 anos) e também nos pacientes do sexo masculino com tremor de ação e postura combinados. A idade de início não foi diferente quando se compararam grupos de pacientes com a mãe ou o pai acometidos. Embora existam diferenças nesta amostra, elas não são suficientes para considerar o TE familiar e o não familiar como entidades distintas.

Palavras-chave: tremor essencial, características clínicas, hereditariedade.


SUMMARY

We reviewed the clinical records of 176 patients with essential tremor (ET) according to sex, age of onset, family history, tremor characteristics and body distribution. The patients were divided into two groups: familial (F) and non familial (NF). A positive family history for tremor was observed in 47,2% of the patients. Action and postural tremor were the most frequent characteristic (49,4%), postural alone in 26,7% and action alone in 9,1%. Rest tremor was recorded in 10,2%, always associated with other characteristics. There were no clinical differences between the F and NF groups. Hands were involved in 94,9% and the head in 26,5%. Isolated tremor of the hands was the most frequent form of presentation with some greater frequency in males. Sixty per cent of the patients who presented head tremor either isolated or not, were females. The presence or absence of family history did not show difference in this proportion. The age of onset ranged between 4 and 85 years. In the F group a lower mean of onset (36,5 years) was seen in males with statistical significance. In male patients with combined action and postural tremor a lower age of onset was found. The fact of a patient having either parent affected by ET produced no difference in the age of onset. Familial or non familial ET bearing some differences, may not be considered as distinct entities.

Key words: essential tremor, clinical characteristics, genetics.


 

 

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

 

 

Agradecimentos: Os autores agradecem o auxílio do CNPq.

 

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Aceite: 21-outubro-1993.

 

 

Este estudo é uma súmula da Dissertação de Mestrado apresentada ao Curso de Pós Graduação em Neurologia da Escola Paulista de Medicina em 1993.
Dra. Vanderci Borges - Rua Cassandoca, 1196 bloco 22 apto.34 - 03169-010 São Paulo SP Brasil.