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Arquivos de Neuro-Psiquiatria

Print version ISSN 0004-282X

Arq. Neuro-Psiquiatr. vol.55 no.2 São Paulo June 1997 

The intracarotid amobarbital procedure (Wada test) with two protocols combined, Montreal and Seattle


Procedimentos do amobarbital intracarotideo (teste de Wada) com dois protocolos combinados, Montreal e Seattle



Paulo J. M. LeiteI; Rosana PereiraIII; Diogo F. AlmeidaIV; Marcos C. SandmannI; Paulo César SouzaV; Ronei SandrinniV; Jorge KaneguzukoV; Paulo Roberto M. de BittencourtII

INeurologist, Program of Epilepsy Surgery, Hospital Nossa Senhora das Graças, Curitiba
IIHead of Neurology and EEC Services, Program of Epilepsy Surgery, Hospital Nossa Senhora das Graças, Curitiba
IIISpeech Therapist, Program of Epilepsy Surgery, Hospital Nossa Senhora das Graças, Curitiba
IVMedical student, Program of Epilepsy Surgery, Hospital Nossa Senhora das Graças, Curitiba
VRadiologist. Program of Epilepsy Surgery, Hospital Nossa Senhora das Graças, Curitiba




The intracarotid amobarbital procedure was carried out in 8 male and 7 female candidates to temporal lobectomy, and a female candidate to frontal lesionectomy, aged 18-50 (mean 32.5) years. Language and memory were tested after injection in each hemisphere. Both were measured by the Montreal procedure. In 9 patients language and memory were evaluated with the Seattle procedure too. In 12 patients the left hemisphere was dominant for language; three had bilateral dominance. In I patient the Seattle procedure demonstrated the dominant hemisphere by relatively slowness of speech during the drug effect in the left hemisphere. Memory was defined to be in the left hemisphere in 12 patients, in the right in 2, bilateral in 1 and in another lateralization was not possible. In 1 patient memory dominance was determined by the Montreal protocol alone because of lack of cooperation. These early results indicate that the methods may be complementary for determination of language and memory dominance in epilepsy surgery candidates.

Key words: amobarbital (Wada) test, epilepsy surgery, language, memory.


O testo do amobarbital intracarotídeo foi realizado em 8 homens e 7 mulheres candidatos a lobectomia temporal e em uma mulher candidata a lesionectomia frontal, com idades de 18-50 (média 32,5) anos. Linguagem e memória foram testadas após a injeção do amobarbial em cada hemisfério cerebral. Todos os pacientes foram avaliados pelo método de Montreal e 9 também pelo método de Seattle. Em 12 pacientes o hemisfério cerebral esquerdo foi dominante para linguagem e em 3 pacientes houve dominância bilateral. Em uma paciente a linguagem foi determinada apenas através do método de Seattle, com lentificação relativa da fal a, sob ação da droga no hemisfério cerebral esquerdo. Dominância da memória à esquerda foi observada em 12 pacientes, à direita em 2, bilateral em 1 e em outro não foi lateralizada. Dominância da memória foi definida apenas através do método de Montreal em um paciente, devido à pouca cooperação. Estes resultados preliminares indicam que os métodos podem ser complementares para a determinação da dominância da linguagem e memória em especial nos candidatos à lobectomia temporal.

Palavras-chave: teste do amobarbital (Wada), cirurgia de epilepsia, linguagem, memória.



Texto completo disponível apenas em PDF.

Full text available only in PDF format.




The authors wish to thank Dr Carl B Dodrill (Seattle, USA) for the advice he has continuously given to the team of the Program for Epilepsy Surgery of Hospital Nossa Senhora das Graçs.



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Aceite: 4-fevereiro-1997.



Dr. Paulo R. M. de Bittencourt - Unidade de Neurologia Clínica - Rua Padre Anchieta 155 - 80410-030 Curitiba PR - Brasil.

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