Meningeomas: aspectos histopatológicos e recidiva

Hilbig, Arlete; Barbosa-Coutinho, Lígia Maria

doi:10.1590/S0004-282X1997000300014

Resumos

Os autores realizaram a avaliação de 246 casos de meningeomas que foram classificados como típico, atípico, anaplásico e papilar segundo critérios previamente definidos. Entre os critérios utilizados para definição de tumores não típicos, a invasão do sistema nervoso central predominou com 62,3% dos casos. Os meningeomas foram típicos em 75,22% dos casos, atípicos em 19,1%, anaplásicos em 5,68%. Houve recidiva em 3,78% dos meningeomas típicos, em 42,55% dos atípicos e 45,45% dos anaplásicos. Os autores concluem que os critérios utilizados para definição de típicos e não típicos foram adequados para predizer maior chance de recidiva tumoral.

meningeomas; histopatologia; recidiva

The authors assessed 246 cases of meningiomas that were classified as typical, atypical, anaplastic and papillary, according to previously defined criteria. Among the criteria used to define non-typical tumours, brain invasion was predominant in 62.3%. Meningiomas were typical in 75.22%, atypical in 19.1 %, anaplastic in 5.68% of the cases. There was recurrence in 3.78% of typical, 42.55% of atypical and 45.45% of anaplastic. The authors conclusion was that the criteria used to define typical and non-typical were adequate to predict a higher chance to tumour recurrence.

meningiomas; histopathology; recurrence

Meningeomas: aspectos histopatológicos e recidiva

Meningiomas: histopathological aspects and recurrence

Arlete Hilbig^I; Lígia Maria Barbosa-Coutinho^II

^INeurologista, Mestre em Clínica Médica pela Universidade Federal do Rio Grande do Sul

^IIProfessora Titular de Anatomia Patológica da FFFCMPA, Livre-Docente em Anatomia Patológica, Neuropatologista

RESUMO

Os autores realizaram a avaliação de 246 casos de meningeomas que foram classificados como típico, atípico, anaplásico e papilar segundo critérios previamente definidos. Entre os critérios utilizados para definição de tumores não típicos, a invasão do sistema nervoso central predominou com 62,3% dos casos. Os meningeomas foram típicos em 75,22% dos casos, atípicos em 19,1%, anaplásicos em 5,68%. Houve recidiva em 3,78% dos meningeomas típicos, em 42,55% dos atípicos e 45,45% dos anaplásicos. Os autores concluem que os critérios utilizados para definição de típicos e não típicos foram adequados para predizer maior chance de recidiva tumoral.

Palavras-chave: meningeomas, histopatologia, recidiva.

ABSTRACT

The authors assessed 246 cases of meningiomas that were classified as typical, atypical, anaplastic and papillary, according to previously defined criteria. Among the criteria used to define non-typical tumours, brain invasion was predominant in 62.3%. Meningiomas were typical in 75.22%, atypical in 19.1 %, anaplastic in 5.68% of the cases. There was recurrence in 3.78% of typical, 42.55% of atypical and 45.45% of anaplastic. The authors conclusion was that the criteria used to define typical and non-typical were adequate to predict a higher chance to tumour recurrence.

Key words: meningiomas, histopathology, recurrence.

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Aceite: 4-abril-1997.

Dra. Aríete Hilbig - Rua Dona Laura 570 - 90430-090 Porto Alegre RS - Brasil.

1. Böker DK, Meurer H, Gullotta P. Recurring intracranial meningiomas: evaluation of some factors predisposing for tumor recurrence. J Neurosurg Sci 1985;29:11-17.
2. Fogelholm R, Uutela T, Munos K. Epidemiology of central nervous system neoplasms: a regional survey in central Finland. Acta Neurol Scand 1984;69:129-136.
3. Jaaskelainen J, Haltia M, Laasonen E. The growth rate of intracranial meningiomas and its relation to histology. Surg Neurol 1985;24:165-172.
4. Jaaskelainen J, Haltia M, Servo A. Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy and outcome. Surg Neurol 1986;25:233-242.
5. Kepes JJ. The histopathology of meningiomas: a reflection of origins and expected behavior? J Neuropathol Exper Neurol 1986;45:95-107.
6. Kleihues P, Burger PC, Scheithauer BW The new WHO classification of brain tumors. Brain Pathol 1993;3:255-268.
7. Kostron H, Daxenbichler G, Maier H. Steroidrezeptoren und atypische Histologie als prognostische Parameter bei Meningiomen. Wiener Klin Wochenschrift 1990;18:525-528.
8. Maier H, Ofner D, Hittmair A et al. Classical, atypical and anaplastic meningiomas: three histopathological subtypes of clinical relevance. J Neurosurg 1992;77:616-623.
9. Markwalder TM, Zava DT, Goldhirsch A, Markwalder RV. Estrogen and progesterone receptors in meningiomas in relation to clinical and pathologic features. Surg Neurol 1983;20:42-47.
10. May PL, Broome JC, Path MRC et al. The prediction of recurrence in meningiomas. J Neurosurg 1989;71:347-351.
11. Melamed S, Sahar A, Beller AJ. The recurrence of intracranial meningiomas. Neurochirurgia 1979;22:47-51.
12. Russell DS, Rubinstein LI. Pathology of tumors of the nervous system. Ed 5. London: Edward Arnold, 1989.
13. Schoenberg BS, Christine BW, Whisnant JP. The descriptive epidemiology of primary intracranial neoplasms: the Connecticut experience. Am J Epidemiol 1976;104:499-510.
14. Walker AE, Robins M, Weinfeld FD. Epidemiology of brain tumours: the national survey of intracranial neoplasms. Neurology 1985;35:219-226.
15. Wertheimer P, Lapras C, Tommasi M et al. A propôs des méningiomes récidivants et de huit observations. Neurochirurgie 1959;2:72-90.
16. Younis GA, Sawaya R, De Monte F et al. Aggressive meningeal tumors: review of a series. J Neurosurg 1995;82:17-27.
17. Zulch KJ. Brain tumors: their biology and pathology, Ed 3. Berlin: Springer-Verlag, 1986.

Datas de Publicação

Publicação nesta coleção
18 Out 2010
Data do Fascículo
Set 1997

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Böker DK, Meurer H, Gullotta P. Recurring intracranial meningiomas: evaluation of some factors predisposing for tumor recurrence. J Neurosurg Sci 1985;29:11-17.

[2] 2. Fogelholm R, Uutela T, Munos K. Epidemiology of central nervous system neoplasms: a regional survey in central Finland. Acta Neurol Scand 1984;69:129-136.

[3] 3. Jaaskelainen J, Haltia M, Laasonen E. The growth rate of intracranial meningiomas and its relation to histology. Surg Neurol 1985;24:165-172.

[4] 4. Jaaskelainen J, Haltia M, Servo A. Atypical and anaplastic meningiomas: radiology, surgery, radiotherapy and outcome. Surg Neurol 1986;25:233-242.

[5] 5. Kepes JJ. The histopathology of meningiomas: a reflection of origins and expected behavior? J Neuropathol Exper Neurol 1986;45:95-107.

[6] 6. Kleihues P, Burger PC, Scheithauer BW The new WHO classification of brain tumors. Brain Pathol 1993;3:255-268.

[7] 7. Kostron H, Daxenbichler G, Maier H. Steroidrezeptoren und atypische Histologie als prognostische Parameter bei Meningiomen. Wiener Klin Wochenschrift 1990;18:525-528.

[8] 8. Maier H, Ofner D, Hittmair A et al. Classical, atypical and anaplastic meningiomas: three histopathological subtypes of clinical relevance. J Neurosurg 1992;77:616-623.

[9] 9. Markwalder TM, Zava DT, Goldhirsch A, Markwalder RV. Estrogen and progesterone receptors in meningiomas in relation to clinical and pathologic features. Surg Neurol 1983;20:42-47.

[10] 10. May PL, Broome JC, Path MRC et al. The prediction of recurrence in meningiomas. J Neurosurg 1989;71:347-351.

[11] 11. Melamed S, Sahar A, Beller AJ. The recurrence of intracranial meningiomas. Neurochirurgia 1979;22:47-51.

[12] 12. Russell DS, Rubinstein LI. Pathology of tumors of the nervous system. Ed 5. London: Edward Arnold, 1989.

[13] 13. Schoenberg BS, Christine BW, Whisnant JP. The descriptive epidemiology of primary intracranial neoplasms: the Connecticut experience. Am J Epidemiol 1976;104:499-510.

[14] 14. Walker AE, Robins M, Weinfeld FD. Epidemiology of brain tumours: the national survey of intracranial neoplasms. Neurology 1985;35:219-226.

[15] 15. Wertheimer P, Lapras C, Tommasi M et al. A propôs des méningiomes récidivants et de huit observations. Neurochirurgie 1959;2:72-90.

[16] 16. Younis GA, Sawaya R, De Monte F et al. Aggressive meningeal tumors: review of a series. J Neurosurg 1995;82:17-27.

[17] 17. Zulch KJ. Brain tumors: their biology and pathology, Ed 3. Berlin: Springer-Verlag, 1986.