Doença de Binswanger: estudo anátomo-clínico de um caso

Brito-Marques, Paulo Roberto de; Mello, Roberto Vieira de

doi:10.1590/S0004-282X1997000400021

Resumos

Descreve-se o caso de uma paciente com doença de Binswanger e que foi acompanhada durante 10 anos, antes e depois da síndrome demencial. O diagnóstico clínico ficou estabelecido pela história, exames clinico e neurológico, e avaliação neuropsicológica. As imagens de tomografia cerebral computadorizada e, principalmente, de ressonância magnética do crânio sugeriram o diagnóstico, o qual foi confirmado pelo estudo anátomo-patológico. Comentam-se os dados clínicos e comportamentais, aspectos de ordem radiológica e histopatológica, confrontando-os à literatura.

demência; doença de Binswanger; hipertensão arterial sistêmica

The authors describe a case of Binswanger's disease in a female patient with arterial hypertension followed during 10 years, before and after the demential syndrome. The clinical diagnosis was established through history, clinical and neurological examination, and neuropsychologic evaluation. Computed tomography and particularly magnetic resonance imaging suggested the diagnosis, that was confirmed by the anatomo-pathological study. They discuss behavioral and clinical data, and radiological and histopathologic aspects, comparing them with data found in the literature.

dementia; Binswanger's disease; systemic arterial hypertension

Doença de Binswanger: estudo anátomo-clínico de um caso

Binswanger's disease: case report

Paulo Roberto de Brito-Marques^I; Roberto Vieira de Mello^II

^IProfessor Assistente da Disciplina de Neurologia da Faculdade de Ciências Médicas (DN-FCM) da Universidade de Pernambuco (UPE), Coordenador do Núcleo de Neurologia Cognitiva e do Comportamento (NC) da DN-FCM-UPE

^IIProfessor Adjunto do Departamento de Patologia do Centro de Ciências da Saúde da Universidade Federal de Pernambuco, Neuropatologista Associado do NC-DN-FCM-UPE

RESUMO

Descreve-se o caso de uma paciente com doença de Binswanger e que foi acompanhada durante 10 anos, antes e depois da síndrome demencial. O diagnóstico clínico ficou estabelecido pela história, exames clinico e neurológico, e avaliação neuropsicológica. As imagens de tomografia cerebral computadorizada e, principalmente, de ressonância magnética do crânio sugeriram o diagnóstico, o qual foi confirmado pelo estudo anátomo-patológico. Comentam-se os dados clínicos e comportamentais, aspectos de ordem radiológica e histopatológica, confrontando-os à literatura.

Palavras-chave: demência, doença de Binswanger, hipertensão arterial sistêmica.

ABSTRACT

The authors describe a case of Binswanger's disease in a female patient with arterial hypertension followed during 10 years, before and after the demential syndrome. The clinical diagnosis was established through history, clinical and neurological examination, and neuropsychologic evaluation. Computed tomography and particularly magnetic resonance imaging suggested the diagnosis, that was confirmed by the anatomo-pathological study. They discuss behavioral and clinical data, and radiological and histopathologic aspects, comparing them with data found in the literature.

Key-words: dementia, Binswanger's disease, systemic arterial hypertension.

Texto completo disponível apenas em PDF.

Full text available only in PDF format.

Aceite: 17-junho-1997.

Dr. Paulo Roberto Brito-Marques - Rua Santa Terezinha, 58 - 53140-170 Olinda PE - Brasil.

1. Brun A, Englund E. A white matter disorder in dementia of the Alzheimer type: a patho-anatomical study. Ann Neurol 1986;19:253-262.
2. Caplan LR. Binswanger's disease. Handbook of clinical neurology, Vol 2 (46): Neurobehavioural disorders. Amsterdam: Elsevier, 1985:317-321.
3. Caplan LR. Binswanger's disease revisited. Neurology 1995,45:626-633.
4. Englund E, Brun A, Ailing C. White matter changes in dementia of Alzheimer's disease type: biochemical and neuropathological correlates. Brain 1988;111:1425-1439.
5. Fisher CM. Binswanger's encephalopathy: a review. J Neurol 1989;236:65-79.
6. Garcia-Albea E, Cabello A, Frach O. Subcortical arteriosclerotic encephalopathy (Binswanger's disease): a report of five patients. Acta Neurol Scand 1987;75:295-303.
7. George AE, de León MJ, Gentes CI, Miller J, London E, Budzilovich GN, Chase N. Leukoencephalophaty in normal and pathological aging: 1. CT of brain Iucencies. AJNR 1986;7:561-566.
8. Gray F, Dubas, F, Roullet E, Escourolle R. Leukoencecephalopathy in diffuse hemorrhagic amyloid angiopathy. Ann Neurol 1985;141:93-108.
9. Jellinger K, Neumayer E. Progressive subcorticale vasculare Encephalopathie Binswanger. Arch Psychiatr ges Neurol 1964;205:523-554.
10. Olszewki J. Subcortical arteriosclerotic encephalopaty: review of the literature on the so-called Binswanger's disease and presentation of two cases. World Neurol 1965;3:359-373.
11. Saussure RV. Philippe Pinel. In: Kolle, K.Grosse Nervenärste. Stutgart: Georg Thieme Verlag, 1970:216-235.
12. Vega MG, Faccio EJ. Enfermedad de Binswanger: evolucion de las ideas y propuesta de un tripode diagnóstico. Arq Neuropsiquiatr 1995;53:518-525.

Datas de Publicação

Publicação nesta coleção
18 Out 2010
Data do Fascículo
Set 1997

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. Brun A, Englund E. A white matter disorder in dementia of the Alzheimer type: a patho-anatomical study. Ann Neurol 1986;19:253-262.

[2] 2. Caplan LR. Binswanger's disease. Handbook of clinical neurology, Vol 2 (46): Neurobehavioural disorders. Amsterdam: Elsevier, 1985:317-321.

[3] 3. Caplan LR. Binswanger's disease revisited. Neurology 1995,45:626-633.

[4] 4. Englund E, Brun A, Ailing C. White matter changes in dementia of Alzheimer's disease type: biochemical and neuropathological correlates. Brain 1988;111:1425-1439.

[5] 5. Fisher CM. Binswanger's encephalopathy: a review. J Neurol 1989;236:65-79.

[6] 6. Garcia-Albea E, Cabello A, Frach O. Subcortical arteriosclerotic encephalopathy (Binswanger's disease): a report of five patients. Acta Neurol Scand 1987;75:295-303.

[7] 7. George AE, de León MJ, Gentes CI, Miller J, London E, Budzilovich GN, Chase N. Leukoencephalophaty in normal and pathological aging: 1. CT of brain Iucencies. AJNR 1986;7:561-566.

[8] 8. Gray F, Dubas, F, Roullet E, Escourolle R. Leukoencecephalopathy in diffuse hemorrhagic amyloid angiopathy. Ann Neurol 1985;141:93-108.

[9] 9. Jellinger K, Neumayer E. Progressive subcorticale vasculare Encephalopathie Binswanger. Arch Psychiatr ges Neurol 1964;205:523-554.

[10] 10. Olszewki J. Subcortical arteriosclerotic encephalopaty: review of the literature on the so-called Binswanger's disease and presentation of two cases. World Neurol 1965;3:359-373.

[11] 11. Saussure RV. Philippe Pinel. In: Kolle, K.Grosse Nervenärste. Stutgart: Georg Thieme Verlag, 1970:216-235.

[12] 12. Vega MG, Faccio EJ. Enfermedad de Binswanger: evolucion de las ideas y propuesta de un tripode diagnóstico. Arq Neuropsiquiatr 1995;53:518-525.