Abstracts
Schwannoma é um tumor neurogênico benigno raro, originário das células de Schwann da bainha de mielina dos nervos periféricos. Sua localização nos tecidos oculares não é comum, sendo a órbita o local afetado com maior frequência e o acometimento das pálpebras é muito raro. Há poucos relatos descritos na literatura sobre Schwannoma palpebral, apenas dois em crianças. Este é, em nosso conhecimento, o primeiro caso relatado no Brasil.
Neurilemoma/patologia; Neurilemoma//cirurgia; Neoplasias palpebrais/patologia; Neoplasias palpebrais/cirurgia; Criança; Relatos de casos
Schwannoma is a rare benign neurogenic tumor. It arises from Schwann cells located at the myelin sheath of peripheral nerves. Its incidence is frequently associated with the orbit. Ocular tissues in general and eyelids in particular are rarely affected. Very few reports can be found in the literature describing eyelid schwannomas. Amongst these, we have found only two describing it affecting children. To our knowledge, this is the first case report about eyelid schwanomma in Brazil - and it involves a child.
Neurilemmoma/pathology; Neurilemmoma/surgery; Eyelid neoplasms/pathology; Eyelid neoplasms/surgery; Child; Case reports
INTRODUCTION
Schwannoma or neurilemmoma is a rare benign neurogenic tumour originating from the
Schwann cells of the myelin sheath of peripheral nerves(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.
2. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
7. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
10. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.-1111. Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol.
1960;44:252.). It is a slow-growing encapsulated tumour that seldom
affects ocular tissues. The orbit is the most frequently-affected site (1-2% of all
orbital tumours), while the eyelids are very rarely involved(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.
2. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
7. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
10. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.-1111. Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol.
1960;44:252.). It usually develops in adults as an isolated tumour or in
association with neurofibromatosis(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.). When
isolated it is rarely associated with neurofibromatosis(55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.), since the presence of multiple
schwannomas is usually indicative of the condition(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.).
There are few reports of eyelid schwannoma in the literature(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.
2. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
7. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
10. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.-1111. Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol.
1960;44:252.), and the case reported here is, to our knowledge, the first
in Brazil.
CASE REPORT
Ten-year-old female patient complaining of a lump in the lateral corner of the upper left eyelid; the patient was diagnosed with chalazion and underwent surgical excision. During surgery it was noted that the lesion's appearance was not compatible with the medical diagnosis of chalazion, but suggestive of a hard, well-demarcated tumour of the subcutaneous tissue with benign features.The lesion was excised and submitted to histopathology. Macroscopic examination showed an irregular fragment of whitish, compact, elastic tissue measuring 1.1 x 0.7 x 0.2 cm. Microscopic examination showed histological sections consisting of spindle-shaped cells with oval nuclei and elongated oval cytoplasm forming bundles, most of them loose, corresponding to the Antoni A pattern for schwannoma, as well as small areas corresponding to the Antoni B pattern (Figure 1A). The lesion was diagnosed as a schwannoma (neurilemmoma) with a histopathological predominance of the Antoni A pattern.
A) Histological sections showing a proliferation of spindleshaped cells with oval nuclei and elongated oval cytoplasm forming bundles, most of them loose, corresponding to the Antoni A pattern for schwannoma, as well as small areas corresponding to the Antoni B pattern. B) The tissue was immunopositive for the S-100 protein.
Immunohistochemical examination of the lesion showed that the tissue was immunopositive for the S-100 protein and immunonegative for the other tested proteins (melan-A, smooth muscle actin, GEAP [glial fibrillary acidic protein], and the Ki-67 antigen), with evidence of low cell proliferation (Figure 1B). These tests confirmed the diagnosis of schwannoma.
The patient recovered well postoperatively with complete wound healing. After six months there were no signs of relapse. The patient is still undergoing follow-up.
DISCUSSION
Schwannomas or neurilemmomas are slow-growing benign tumours of the cranial and
peripheral nerves. Their origin is ectodermal and they are derived from the Schwann
cells of the myelin sheath(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.
2. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
7. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.-1010. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.).
Schwannomas are firm encapsulated tumours with solid and cystic areas and a
brown-yellow colour. They are asymptomatic(55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.).
Schwannomas can be associated with neurofibromatosis, but when isolated they are not related to this condition(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol. 2009;57(4):318-20.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.).
Schwannomas occur in two histological patterns.The Antoni A pattern, found in the patient presented here, presents with spindle-shaped cells arranged in compact stacks, usually in palisades.The Antoni B pattern is characterised by cells dispersed in a myxoid matrix(33. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.,66. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.).
Eyelid schwannomas are extremely rare and usually occur in adults(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.-77. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.,99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.,1010. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.). Only two other cases have been
reported in children(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.,88. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.). The
patient presented here was 10 years old at the time of diagnosis. Among the cases
reported in the literature, the incidence in males and females seems to be similar
(there are reports of schwannoma in 6 males 8 females, including the case presented
here) (Table 1).
Ocular schwannomas are more common in the orbit, representing 1-2% of orbital tumours(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower eyelid in a 13-year-old girl.Ophthal Plast Reconstr Surg.2009;25(1):50-2.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.,66. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.), while eyelid schwannomas are extremely rare(66. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.,99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.). There are also reports of schwannomas in the conjunctiva, sclera, and uveal tract(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower eyelid in a 13-year-old girl.Ophthal Plast Reconstr Surg.2009;25(1):50-2.,22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol. 2009;57(4):318-20.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.,99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.). Orbital schwannomas usually originate from the oculomotor, ciliary, and supraorbital nerves. Eyelid schwannomas are believed to originate from branches of the supraorbital, supratrochlear, and infraorbital nerves(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower eyelid in a 13-year-old girl.Ophthal Plast Reconstr Surg.2009;25(1):50-2.).
Schwannomas manifest clinically as solid, painless, slowgrowing masses which are often confused with chalazion(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol. 2009;57(4):318-20.,44. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J Ophthalmol. 2007;51(3):231-2.,99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.) or inclusion cysts(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol. 2009;57(4):318-20.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.). The differential diagnosis should include chalazion, sweat gland tumour, sebaceous gland carcinoma, hair follicle tumour, and other neurogenic and soft tissue tumours(99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.).
Schwannomas can rarely become malignant(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.). Computed tomography is important to delineate the tumour
for surgery, as the lesion has to be excised completely to prevent relapse or
malignant transformation(44. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.,77. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
10. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.-1111. Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol.
1960;44:252.).
The diagnosis of eyelid schwannoma can be suggested by clinical examination and
imaging studies in conjunction with its macroscopic appearance during surgery;
however, because the condition is so rare, it is seldom considered in the
differential diagnosis of eyelid masses and the diagnosis is often made by
histopathological examination(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower
eyelid in a 13-year-old girl.Ophthal Plast Reconstr
Surg.2009;25(1):50-2.
2. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.
3. Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in
an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
4. Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J
Ophthalmol. 2007;51(3):231-2.
5. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.
6. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a
male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
7. Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as
a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
8. Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of
the eyelid in a child. J Pediatr Ophthalmol
Strabismus.1994;31(5):332-3.
9. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a
recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
10. Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid.
Indian J Ophthalmol.1980;28(3):155-6.-1111. Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol.
1960;44:252.), as was
the case with our patient. However, it is a hypothesis to be considered, especially
in cases of recurrent chalazion. It is also important to search for similar lesions
in other areas of the body in order to investigate neurofibromatosis, since
schwannomas can be associated with this condition(22. Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma
of the eyelid: apropos of two cases. Indian J Ophthalmol.
2009;57(4):318-20.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR.
Schwannoma of the eyelid: report of two cases. Dermatol Online
J.2007;13(2):12.). In our case no signs of the disease were found.
Schwannomas in the ocular region are rare, although they represent approximately 1-2% of orbital tumours(11. Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower eyelid in a 13-year-old girl.Ophthal Plast Reconstr Surg.2009;25(1):50-2.,55. López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.,66. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.). Eyelid schwannomas are extremely rare(66. Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.,99. Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.). Although uncommon, schwannomas should be included in the differential diagnosis of any eyelid tumour.
-
Institution: Recife Eye Institute, Recife/PE, Brazil;
REFERÊNCIAS
-
1Onaran Z, Ornek K, Yilmazbas P, Bozdogan O. Schwannoma of the lower eyelid in a 13-year-old girl.Ophthal Plast Reconstr Surg.2009;25(1):50-2.
-
2Touzri RA, Errais K, Zermani R, Benjilani S, Ouertani A. Schwannoma of the eyelid: apropos of two cases. Indian J Ophthalmol. 2009;57(4):318-20.
-
3Kumar S, Kumar S, Kulshrestha R. Cystic schwannoma of the eyelid in an Indian male: a rare presentation.Orbit. 2008; 27(6):407-9.
-
4Chung YR, Moon S, Jang JW. Eyelid schwannoma in a Korean woman. Jpn J Ophthalmol. 2007;51(3):231-2.
-
5López-Tizón E, Mencía-Gutiérrez E, Gutiérrez-Díaz E, Ricoy JR. Schwannoma of the eyelid: report of two cases. Dermatol Online J.2007;13(2):12.
-
6Siddiqui MA, Leslie T, Scott C, Mackenzie J. Eyelid schwannoma in a male adult. Clin Experiment Ophthalmol.2005;33(4):412-3.
-
7Butt Z, Ironside JW. Superficial epithelioid schwannoma presenting as a subcutaneous upper eyelid mass. Br J Ophthalmol. 1994;78(7):586-8.
-
8Shields JA, Kiratli H, Shields CL, Eagle RC Jr, Luo S. Schwannoma of the eyelid in a child. J Pediatr Ophthalmol Strabismus.1994;31(5):332-3.
-
9Shields JA, Guibor P. Neurilemoma of the eyelid resembling a recurrent chalazion. Arch Ophthalmol.1984;102(11):1650.
-
10Baijal GC, Garg SK, Kanhere S, Monga S. Schwannoma of the eye-lid. Indian J Ophthalmol.1980;28(3):155-6.
-
11Mishra S, Sharan J. Palpebral neurilemmoma. Br J Ophthalmol. 1960;44:252.
Publication Dates
-
Publication in this collection
Mar-Apr 2014
History
-
Received
10 June 2011 -
Accepted
29 Sept 2012