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Revista do Instituto de Medicina Tropical de São Paulo

versión On-line ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.26 no.1 São Paulo enero/feb. 1984

https://doi.org/10.1590/S0036-46651984000100009 

Inquérito soroepidemiológico sobre malária em escolares de Marabá, Pará

 

Malaria soroepidemiologic survey in school population of Marabá, Pará

 

 

Marcos BoulosI; Antonio Carlos CenevivaII; Mário ShiromaIII; Mário E. CamargoIV; Euclides A. de CastilhoV

IProf. Assistente do Departamento de Medicina Tropical e Dermatologia da Faculdade de Medicina da USP
IIResponsável pelo Setor de Malária do Laboratório de Imunologia do Instituto de Medicina Tropical da USP
IIIProfessor Adjunto do Departamento de Medicina Tropical e Dermatologia da Faculdade de Medicina da USP
IVProf. Assist. Dr. Chefe do Laboratório de Imunologia do Instituto de Medicina Tropical de São Paulo da Faculdade de Medicina da USP
VProf. Adjunto do Departamento de Medicina Preventiva da Faculdade de Medicina da USP

 

 


RESUMO

Realizou-se inquérito sorológico para malária em escolares de Marabá — Pará, por meio de testes de imunofluorescência (IP) para anticorpos IgG e IgM, tendo como antígenos P. falciparum e P. gallinaceum, e teste de hemaglutinação (HAg) com P. gallinaceum. O teste IF-IgG com P. falciparum foi positivo em 6,94% dos 389 indivíduos estudados e o de P. gallinaceum em 11,56%, havendo concordância entre ambos os testes em 88,68% das amostras. No total, observou-se 14,91% de casos reagentes em qualquer dos testes. O teste com P. gallinaceum se mostrou mais abrangente provavelmente devido a maior prevalência na região de infecções por P. vivax. Ao se dividir a população estudada em faixas etárias de 6 a 10 anos (grupo A) e de 11 a 16 anos (grupo B), observou-se diferença significativa de reatividade ao teste IF-IgG com P. falciparum (2,68% para A e 10,94% para B) mas não com P. gallinaceum (10,10% para A e 12,97% para B). Para os testes IF-IgM houve positividade de 2,83% na população, e para o teste de HAg de 1,80%, sem diferença significativa entre os grupos etários A e B.


SUMMARY

A malaria serologic survey was carried out in first grade school children from Marabá, PA. Immunofluorescence (IF) test was used for the detection of IgG and IgM antibodies to P. falciparum and to P. gallinaceum. Also, hemagglutination (HAg) test with P. gallinaceum infected erythrocytes was employed.
The IF-IgG test with P. falciparum was positive in 6.94% of the 389 individuals studied, and the IF-IgG test with P. gallinaceum in 11.56%. Agreement between both tests 'was observed in 88.68% of sera. A total 14.91% reactive cases were seen by any of the two tests. The IF test using P. gallinaceum as antigen showed higher positivity than P. falciparum probably due to the predominance of T. vivax infection in that area.
A statistically significant difference (P < 0.05) was observed for IF-IgG test with P. falciparum antigen between the age group A (6 to 10 years) and group B (11 to 16 years). However, this was not seen when P. gallinaceum antigen was applied.
The positivity obtained in IF-IgM and HAg tests were respectively 2.83% and 1.80%, with no significant differences between the referred age groups (P > 0.05).


 

 

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Recebido para publicação em 18/11/1982.

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