The prevalence of antibody to human parvovirus B19 in Rio de Janeiro, Brazil

Nascimento, Jussara P.; Buckley, Marie M.; Brown, Kevin E.; Cohen, Bernard J.

doi:10.1590/S0036-46651990000100007

Abstracts

During 1985 and 1986 serum samples were collected from the Rio de Janeiro population and examined for the presence of IgG antibody to human parvovirus B19. No difference in prevalence was found between males and females. Antibody prevalence rose from 35% in children less than five years old to almost 80% in children aged eleven to fifteen years. The antibody prevalence in individuals over 50 years old was over 90%.

Human parvovirus B19 anti-B19 IgG prevalence

Amostras de soros coletadas da população do Rio de Janeiro durante os anos de 1985/1986 foram examinadas para a presença de anticorpos da classe IgG contra o parvovirus humano B19. Nenhuma diferença foi encontrada com relação ao sexo. A prevalência de anticorpos aumenta a partir de 35% em crianças menores que 5 anos de idade até 80% nos indivíduos na faixa etária entre 11 e 15 anos. A prevalência de anticorpos seguiu aumentando ate mais de 90% entre os indivíduos acima de 50 anos de idade.

EPIDEMIOLOGY

The prevalence of antibody to human parvovirus B19 in Rio de Janeiro, Brazil

Prevalência de anticorpos para o parvovirus humano B19 na população do Rio de Janeiro, Brasil

Jussara P. Nascimento^I,II; Marie M. Buckley^II; Kevin E. Brown^II; Bernard J. Cohen^II

^IDepartamento de Virologia, Fundação Instituto Oswaldo Cruz, Rio de Janeiro, Brasil

^IIVirus Reference Laboratory, Central Public Health Laboratory, London, UK

^{Address for correspondence} Address for correspondence: Dra. Jussara P. Nascimento Departamento de Virologia, Fundação instituto Oswaldo Cruz Caixa Postal 926 CEP 20010, Rio de Janeiro, Brasil

SUMMARY

During 1985 and 1986 serum samples were collected from the Rio de Janeiro population and examined for the presence of IgG antibody to human parvovirus B19. No difference in prevalence was found between males and females. Antibody prevalence rose from 35% in children less than five years old to almost 80% in children aged eleven to fifteen years. The antibody prevalence in individuals over 50 years old was over 90%.

Key words: Human parvovirus B19 anti-B19 IgG prevalence.

RESUMO

Amostras de soros coletadas da população do Rio de Janeiro durante os anos de 1985/1986 foram examinadas para a presença de anticorpos da classe IgG contra o parvovirus humano B19. Nenhuma diferença foi encontrada com relação ao sexo. A prevalência de anticorpos aumenta a partir de 35% em crianças menores que 5 anos de idade até 80% nos indivíduos na faixa etária entre 11 e 15 anos. A prevalência de anticorpos seguiu aumentando ate mais de 90% entre os indivíduos acima de 50 anos de idade.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

ACKNOWLEDGEMENTS

We would like to thank A. S. Cruz from the National Influenza Centre, FIOCRUZ for selecting and sending the sera to the Central Public Health Laboratory in London where this work was done. The work was partially supported by a grant from the Commission of the European Communities. We are also grateful to Dr. P. P. Mortimer for his critical reading of the manuscript and to Miss Debra L. Williams for preparing the report.

Recebido para publicação em 7/6/1989.

1. AGER, E.A.; CHIN, T.D.Y. & POLAND, J.D. - Epidemic erythema infectiosum. New Engl. J. Med., 275: 1326-1331, 1966.
2. ANDERSON, L.J.; TSOU, C.; PARKER, R.A.; CHORBA, T.L.; WULFF, H.; TATTERSALL, P. & MORTIMER, P.P. - Detection of antibodies and antigens of human parvovirus B19 by enzyme-linked immunosorbent assay. J. clin. Microbiol., 24: 522-526, 1986.
3. ANDERSON. L.J & HURWITZ, E.S. - Human parvovirus B19 and pregnancy. Clin. Perinatol.,15: 273-286, 1988.
4. ANDERSON, M.J.; LEWIS, E.; KIDD, I.M.; HALL, S.M. & COHEN, B.J. - An outbreak of erythema infectiosum associated with human parvovirus infection. J. Hyg. (Lond.), 93: 85-93, 1984.
5. ANDERSON, M.J.; HIGGINS, P.G.; DAVIS, L.R.; WILLMAN, J.S.; JONES, S.E.; KIDD, I.M.; PATTISON, J.R. & TYRELL, D.A.J. - Experimental parvoviral infection in humans. J. infect. Dis., 152: 257-265, 1985.
6. ANDERSON, M.J. & CHERRY, J.D. - Parvovirus. In: FEIGIN, R.D. & CHERRY, J.D. - Textbook of pediatric infectious diseases. 2nd. ed. Philadelphia, W.B. Saunders. 1987. p. 1646-1652.
7. COHEN, B.J.; HEWISH, R.A. & MORTIMER, P.P. - Comparison of radioimnunoassay and counter-immuno eleclrophoresis for the detection of antibody to hepatitis B core antigen. J. virol. Meth., 2: 181-192, 1981.
8. COHEN, B.J.; MORTIMER, P.P. & PEREIRA, M.S. - Diagnosis assays with monoclonal antibodies for the human serum parvovirus-like virus (SPLV). J. Hyg. (Lond.), 91: 113-130, 1983.
9. COHEN, B.J. & BUCKLEY, M.M. - The prevalence of antibody to human parvovirus B19 in England and Wales. J. med. Microbiol., 25: 151-153, 1988.
10. COSSART, Y.E.; FIELD, A.M.; CANT, B. & WIDDOWS, K. - Parvovirus like particles in human sera. Lancet, 1: 72-73, 1975.
11. CRAMP, H.E. & ARMSTRONG, B.D.J. - Erythema infectiosum: an outbreak of "Slapped cheek" disease in north Devon. Brit. med. J., 1: 885-886, 1976.
12. CRUZ, A.S.; SERPA, M.J.A.; BARTH, O.M. & NASCIMENTO, J.P. - Detection of the human parvovirus B19 in a blood donor plasma in Rio de Janeiro. Mem. Inst. Oswaldo Cruz, 84: 279-280, 1989.
13. EDWARDS, J.M.B.; KESSEL, J.; GARDNER, S.D.; EATON, B.R.; POLLOCK, T.M.; FLECK, D.G.; GIBSON, P.; WOODROOF, M. & PORTER, A.D. - A search for a characteristic illness in children with serological evidence of viral or toxoplasma infection. J. Infect., 3: 316-323, 1981.
14. FREITAS, R.B.; LINHARES, A.C.; MIRANDA, M.F.R. & GABBAY, Y. - Novo agente de doença exantematica na Amazônia: o parvovirus "B19". Bol. epidem. (Rio de Janeiro.), 20: 104, 1988.
15. KOCH, W.C. & ADLER, S.P. - Human parvovirus B19 infections in women of childbearing age and within families. Pediat. infect. Dis. J., 8: 83-87, 1989.
16. LAUER, B.A.; MACCORMACK, J.N. & WILFERT, C. - Erythema infectiosum: An elementary school outbreak. Amer. J. Dis. Child., 130: 252-254, 1976.
17. MORI, J.; BEATTIE, P.; MELTON, D.W.; COHEN, B.J. & CLEWLEY, J.P. - Structure and mapping of the DNA of human parvovirus B19. J. gen. Virol., 68: 2797-2806, 1987.
18. NASCIMENTO, J.P.; BUCKLEY, M.M.; CRUZ, A. & COHEN, B.J. - Antibodies to human parvovirus B19 in Rio de Janeiro. In: CONGRESSO BRASILEIRO DE VIROLOGIA, 4., Săo Lourenço, 1988. Resumo. p.108.
19. NUNOUE, T.; OKOCHI, K.; MORTIMER, P.P. & COHEN, B.J. - Human parvovirus (B19) and erythema infectiosum. J. Pediat., 107: 38-40, 1985.
20. PATTISON, J.R. - Diseases caused by the human parvovirus B19. Arch. Dis. Childh., 63: 426-427, 1988.
21. SCHWARZ, T.F.; ROGGENDORF, M. & DEINHARDT, F. - Human parvovirus B19 infections in United Kingdom 1984-86. Lancet, 1: 738-739, 1985.
22. SCHWARZ, T.F.; ROGGENDORF, M. & DEINHARDT, F. - Haufigkeit der Parvovirus-B19-Infectionen. Dtsch. med. Wschr., 112: 1526-1531, 1987.
23. THURN, J. - Human parvovirus B19: historical and clinical review. Rev. infect. Dis., 10: 1005-1011, 1988.
24. WOOLF, A.D.; CAMPION, G.V.; CHISHICK, A.; WISER, S.; COHEN, B.J.; KLOUDA, P.T.; CAUL, E.O. & DIEPPE, P.A. - Clinical manifestations of human parvovirus B19 in adults. Arch. intern. Med. (In press)

Address for correspondence:

Dra. Jussara P. Nascimento

Departamento de Virologia, Fundação instituto Oswaldo Cruz

Caixa Postal 926

CEP 20010, Rio de Janeiro, Brasil

Publication Dates

Publication in this collection
13 Sept 2006
Date of issue
Feb 1990

History

Received
07 June 1989

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. AGER, E.A.; CHIN, T.D.Y. & POLAND, J.D. - Epidemic erythema infectiosum. New Engl. J. Med., 275: 1326-1331, 1966.

[2] 2. ANDERSON, L.J.; TSOU, C.; PARKER, R.A.; CHORBA, T.L.; WULFF, H.; TATTERSALL, P. & MORTIMER, P.P. - Detection of antibodies and antigens of human parvovirus B19 by enzyme-linked immunosorbent assay. J. clin. Microbiol., 24: 522-526, 1986.

[3] 3. ANDERSON. L.J & HURWITZ, E.S. - Human parvovirus B19 and pregnancy. Clin. Perinatol.,15: 273-286, 1988.

[4] 4. ANDERSON, M.J.; LEWIS, E.; KIDD, I.M.; HALL, S.M. & COHEN, B.J. - An outbreak of erythema infectiosum associated with human parvovirus infection. J. Hyg. (Lond.), 93: 85-93, 1984.

[5] 5. ANDERSON, M.J.; HIGGINS, P.G.; DAVIS, L.R.; WILLMAN, J.S.; JONES, S.E.; KIDD, I.M.; PATTISON, J.R. & TYRELL, D.A.J. - Experimental parvoviral infection in humans. J. infect. Dis., 152: 257-265, 1985.

[6] 6. ANDERSON, M.J. & CHERRY, J.D. - Parvovirus. In: FEIGIN, R.D. & CHERRY, J.D. - Textbook of pediatric infectious diseases. 2nd. ed. Philadelphia, W.B. Saunders. 1987. p. 1646-1652.

[7] 7. COHEN, B.J.; HEWISH, R.A. & MORTIMER, P.P. - Comparison of radioimnunoassay and counter-immuno eleclrophoresis for the detection of antibody to hepatitis B core antigen. J. virol. Meth., 2: 181-192, 1981.

[8] 8. COHEN, B.J.; MORTIMER, P.P. & PEREIRA, M.S. - Diagnosis assays with monoclonal antibodies for the human serum parvovirus-like virus (SPLV). J. Hyg. (Lond.), 91: 113-130, 1983.

[9] 9. COHEN, B.J. & BUCKLEY, M.M. - The prevalence of antibody to human parvovirus B19 in England and Wales. J. med. Microbiol., 25: 151-153, 1988.

[10] 10. COSSART, Y.E.; FIELD, A.M.; CANT, B. & WIDDOWS, K. - Parvovirus like particles in human sera. Lancet, 1: 72-73, 1975.

[11] 11. CRAMP, H.E. & ARMSTRONG, B.D.J. - Erythema infectiosum: an outbreak of "Slapped cheek" disease in north Devon. Brit. med. J., 1: 885-886, 1976.

[12] 12. CRUZ, A.S.; SERPA, M.J.A.; BARTH, O.M. & NASCIMENTO, J.P. - Detection of the human parvovirus B19 in a blood donor plasma in Rio de Janeiro. Mem. Inst. Oswaldo Cruz, 84: 279-280, 1989.

[13] 13. EDWARDS, J.M.B.; KESSEL, J.; GARDNER, S.D.; EATON, B.R.; POLLOCK, T.M.; FLECK, D.G.; GIBSON, P.; WOODROOF, M. & PORTER, A.D. - A search for a characteristic illness in children with serological evidence of viral or toxoplasma infection. J. Infect., 3: 316-323, 1981.

[14] 14. FREITAS, R.B.; LINHARES, A.C.; MIRANDA, M.F.R. & GABBAY, Y. - Novo agente de doença exantematica na Amazônia: o parvovirus "B19". Bol. epidem. (Rio de Janeiro.), 20: 104, 1988.

[15] 15. KOCH, W.C. & ADLER, S.P. - Human parvovirus B19 infections in women of childbearing age and within families. Pediat. infect. Dis. J., 8: 83-87, 1989.

[16] 16. LAUER, B.A.; MACCORMACK, J.N. & WILFERT, C. - Erythema infectiosum: An elementary school outbreak. Amer. J. Dis. Child., 130: 252-254, 1976.

[17] 17. MORI, J.; BEATTIE, P.; MELTON, D.W.; COHEN, B.J. & CLEWLEY, J.P. - Structure and mapping of the DNA of human parvovirus B19. J. gen. Virol., 68: 2797-2806, 1987.

[18] 18. NASCIMENTO, J.P.; BUCKLEY, M.M.; CRUZ, A. & COHEN, B.J. - Antibodies to human parvovirus B19 in Rio de Janeiro. In: CONGRESSO BRASILEIRO DE VIROLOGIA, 4., Săo Lourenço, 1988. Resumo. p.108.

[19] 19. NUNOUE, T.; OKOCHI, K.; MORTIMER, P.P. & COHEN, B.J. - Human parvovirus (B19) and erythema infectiosum. J. Pediat., 107: 38-40, 1985.

[20] 20. PATTISON, J.R. - Diseases caused by the human parvovirus B19. Arch. Dis. Childh., 63: 426-427, 1988.

[21] 21. SCHWARZ, T.F.; ROGGENDORF, M. & DEINHARDT, F. - Human parvovirus B19 infections in United Kingdom 1984-86. Lancet, 1: 738-739, 1985.

[22] 22. SCHWARZ, T.F.; ROGGENDORF, M. & DEINHARDT, F. - Haufigkeit der Parvovirus-B19-Infectionen. Dtsch. med. Wschr., 112: 1526-1531, 1987.

[23] 23. THURN, J. - Human parvovirus B19: historical and clinical review. Rev. infect. Dis., 10: 1005-1011, 1988.

[24] 24. WOOLF, A.D.; CAMPION, G.V.; CHISHICK, A.; WISER, S.; COHEN, B.J.; KLOUDA, P.T.; CAUL, E.O. & DIEPPE, P.A. - Clinical manifestations of human parvovirus B19 in adults. Arch. intern. Med. (In press)