Subcutaneous phaeohyphomycosis caused by Bipolaris hawaiiensis: a case report

Costa, Alcyr Ribeiro; Porto, Edward; Tabuti, Alceu Hidearu; Lacaz, Carlos da Silva; Sakai-Valente, Neusa Yurico; Maranhão, Wanira Márcia; Rodrigues, Maria Conceição

doi:10.1590/S0036-46651991000100014

Abstracts

A case of phaeohyphomycosis caused by Bipolaris hawaiiensis is reported. The patient, an immunocompetent host, presented a verrucous lesion on the first finger of the left foot. Dematiaceous septate hyphae and yeast-like elements were seen in direct and histological examination. The isolated strain was identified on the basis of micro and macromorphological aspects. Treated with electrocoagulation, the lesions healed and presented no relapse after two years follow-up.

Bipolaris hawaiiensis; Phaeohyphomycosis; Dematiaceous yeast-like cells

Os autores descrevem um caso de feohifomicose com lesão verrucosa no hálux esquerdo. O paciente não apresentava sinais clínicos de deficiência imunológica. Os exames direto e histopatológico mostraram células leveduriformes e poucas hifas septadas, demacióides, essenciais ao diagnóstico desta micose. O cultivo em lâmina permitiu identificar o hifomiceto como Bipolaris hawaiiensis. A eletrocoagulação foi usada como tratamento, com cura do processo, não havendo recidiva após dois anos.

CASE REPORT

Subcutaneous phaeohyphomycosis caused by Bipolaris hawaiiensis. A case report

Feohifomicose subcutánea causada por Bipolaris hawaiiensis. Registro de um caso

Alcyr Ribeiro Costa^I; Edward Porto^II; Alceu Hidearu Tabuti^I; Carlos da Silva Lacaz^II; Neusa Yurico Sakai-Valente^I; Wanira Márcia Maranhão^I; Maria Conceição Rodrigues^III

^IHospital do Servidor Público Estadual "Francisco Morato de Oliveira". Serviço de Dermatologia (Direção: Dr. J. A. S. Sittart). São Paulo, SP, Brasil

^IILaboratório de Micologia Médica Instituto de Medicina Tropical de São Paulo e Laboratório de Investigação Médica, LIM-53 Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo. São Paulo, SP, Brasil

^IIIDivisão de Tisiologia e Pneumologia. Laboratório de Micologia Médica Instituto Clemente Ferreira. São Paulo, SP, Brasil

^{Address for correspondence} Address for correspondence: Prof. Carlos da Silva Lacaz Instituto de Medicina Tropical de São Paulo Av. Dr. Enéas de Carvalho Aguiar, 470 CEP 05403 São Paulo, SP, Brasil

SUMMARY

A case of phaeohyphomycosis caused by Bipolaris hawaiiensis is reported. The patient, an immunocompetent host, presented a verrucous lesion on the first finger of the left foot. Dematiaceous septate hyphae and yeast-like elements were seen in direct and histological examination. The isolated strain was identified on the basis of micro and macromorphological aspects. Treated with electrocoagulation, the lesions healed and presented no relapse after two years follow-up.

Key words: Bipolaris hawaiiensis; Phaeohyphomycosis; Dematiaceous yeast-like cells.

RESUMO

Os autores descrevem um caso de feohifomicose com lesão verrucosa no hálux esquerdo. O paciente não apresentava sinais clínicos de deficiência imunológica. Os exames direto e histopatológico mostraram células leveduriformes e poucas hifas septadas, demacióides, essenciais ao diagnóstico desta micose. O cultivo em lâmina permitiu identificar o hifomiceto como Bipolaris hawaiiensis.

A eletrocoagulação foi usada como tratamento, com cura do processo, não havendo recidiva após dois anos.

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

ACKNOWLEDGEMENTS

We thank to Mrs. Sônia Cecília Damazio for secretarial assistance.

Recebido para publicação em 29/6/1990.

Aceito para publicação em 06/9/1990.

1. ADAM, R.D.; PAQUIN, M.L.; PETERSEN, E.A.; SAUBOLLE, M.A.; RINALDI, M.G.; CORCORAN, J.G.; GALGIANI, J.N. & SOBONYA, R.E. Phaeohyphomycosis caused by the Fungal Genera Bipolaris and Exserohilum A report of 9 cases and review of the literature. Medicine, 65: 203-217, 1986.
2. AJELLO, L. Hyalohyphomycosis and phaeohyphomycosis: two global entities of public health importance. Europ. J. Epidem., 2: 243-251, 1986.
3. ANANDI, V.; SURYAWANSHI, N.B.; KOSHI, G.; PADHYE, A.A. & AJELLO, L. Corneal ulcer caused by Bipolaris hawaiiensis. J. med. Vet. Mycol., 26: 301 306, 1988.
4. BURGES, G.E.; WALLS, C.T. & MAIZE, J.C. Subcutaneous phaeohyphomycosis caused by Exserohilum rostratum in immunocompetent host. Arch. Derm., 123: 1346-1350, 1987.
5. DE HOOG, G.S. On the potentially pathogenic dematiaceous hyphomycetes. In: HOWARD, D.H. & HOWARD, L.F., ed. Fungi pathogenic for humans and animals. Part A. Biology, New York, Marcel Dekker, 1983. p. 149-216.
6. ELLIS, M.B. Dematiaceous Hyphomycetes Kew, Surrey, Commonwealth Mycological Institute, 1976. p. 415.
7. FUSTE, F.J.; AJELLO, L.; THRELKED, R. & HENRY Jr., J.E. Drechslera hawaiiensis: causative agent of a fatal meningo-encephalitis. Sabouraudia, 11: 59-63, 1973.
8. KOENIG, H.; WARTER, A.; BIEVRE, C. de; WALLER, J.; WEITZEBLUM, E. & MORAND, G. Mycose pulmonaire a Drechslera hawaiiensis. Bull. Soc. franç. Mycol. med., 13: 373-376, 1984.
9. KOSHI, G.; ANANDI, V.; KURIEN, M.; KIRUBAKARAN, M.G.; PADHYE, A.A. & AJELLO, L. Nasal phaeohyphomycosis caused by Bipolaris hawaiiensis. J. med. Vet. Mycol., 25: 397-402, 1987.
10. McGINNIS, M.R. Chromoblastomycosis and phaeohyphomycosis: new concepts, diagnosis, and mycology. Amer. Acad. Derm., 8: 1-16, 1983.
11. McGINNIS, M.R.; RINALDI, M.G. & WINN, R.E. Emerging agents of phaeohyphomicosis: pathogenic species of Bipolaris and Exserohilum. J. clin. Microbiol., 24: 250-259, 1986.
12. McGINNIS, M.R. & HILGER, A.E. Infections caused by black fungi (editorial). Arch. Derm., 123: 1300-1302, 1987.
13. MORTON, S.J.; MIDTHUN, K. & MERZ, W.G. Granulomatous encephalitis caused by Bipolaris hawaiiensis. Arch. Path. Lab. Med., 110: 1183 1185, 1986.
14. NELSON, R.R. Cochliobolus intermedius, the perfect stage of Curvularia intermedia. Mycologia, 52: 775 778, 1960.
15. NELSON, R.R. The perfect stage of Helmonthosporium spiciferum. Mycologia, 56: 196-201, 1964.
16. PORTO, E.; TAKAHASHI, N.; HEINS, E.M. & LACAZ, C. da S. Nuevo metodo para microcultivo de hongos. Rev. argent. Micol., 4: 24-29, 1981.
17. RUBEN, S.J.; SCOTT, T.E. & SELTZER, H.M. Intracranial and paranasal sinus infections due to Drechslera. South. med. J., 80: 1057-1058, 1987.
18. STOCKDALE, P.M. Nannizia incurvata gen. nov., sp. nov., a perfect state of Microsporum gypseum (Bodin) Guiart et Grigorakis. Sabouraudia, 1: 41-48, 1961.
19. YOUNG, C.N.; SWART, J.G.; ACKERMAN, D. & DIVID-GE-PITTS, K. Nasal obstruction and bone erosion caused by Drechslera hawaiiensis. J. Laryng., 92: 137-143, 1978.

Address for correspondence:

Prof. Carlos da Silva Lacaz

Instituto de Medicina Tropical de São Paulo

Av. Dr. Enéas de Carvalho Aguiar, 470

CEP 05403 São Paulo, SP, Brasil

Publication Dates

Publication in this collection
12 Sept 2006
Date of issue
Feb 1991

History

Accepted
06 Sept 1990
Received
29 June 1990

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

[1] 1. ADAM, R.D.; PAQUIN, M.L.; PETERSEN, E.A.; SAUBOLLE, M.A.; RINALDI, M.G.; CORCORAN, J.G.; GALGIANI, J.N. & SOBONYA, R.E. Phaeohyphomycosis caused by the Fungal Genera Bipolaris and Exserohilum A report of 9 cases and review of the literature. Medicine, 65: 203-217, 1986.

[2] 2. AJELLO, L. Hyalohyphomycosis and phaeohyphomycosis: two global entities of public health importance. Europ. J. Epidem., 2: 243-251, 1986.

[3] 3. ANANDI, V.; SURYAWANSHI, N.B.; KOSHI, G.; PADHYE, A.A. & AJELLO, L. Corneal ulcer caused by Bipolaris hawaiiensis. J. med. Vet. Mycol., 26: 301 306, 1988.

[4] 4. BURGES, G.E.; WALLS, C.T. & MAIZE, J.C. Subcutaneous phaeohyphomycosis caused by Exserohilum rostratum in immunocompetent host. Arch. Derm., 123: 1346-1350, 1987.

[5] 5. DE HOOG, G.S. On the potentially pathogenic dematiaceous hyphomycetes. In: HOWARD, D.H. & HOWARD, L.F., ed. Fungi pathogenic for humans and animals. Part A. Biology, New York, Marcel Dekker, 1983. p. 149-216.

[6] 6. ELLIS, M.B. Dematiaceous Hyphomycetes Kew, Surrey, Commonwealth Mycological Institute, 1976. p. 415.

[7] 7. FUSTE, F.J.; AJELLO, L.; THRELKED, R. & HENRY Jr., J.E. Drechslera hawaiiensis: causative agent of a fatal meningo-encephalitis. Sabouraudia, 11: 59-63, 1973.

[8] 8. KOENIG, H.; WARTER, A.; BIEVRE, C. de; WALLER, J.; WEITZEBLUM, E. & MORAND, G. Mycose pulmonaire a Drechslera hawaiiensis. Bull. Soc. franç. Mycol. med., 13: 373-376, 1984.

[9] 9. KOSHI, G.; ANANDI, V.; KURIEN, M.; KIRUBAKARAN, M.G.; PADHYE, A.A. & AJELLO, L. Nasal phaeohyphomycosis caused by Bipolaris hawaiiensis. J. med. Vet. Mycol., 25: 397-402, 1987.

[10] 10. McGINNIS, M.R. Chromoblastomycosis and phaeohyphomycosis: new concepts, diagnosis, and mycology. Amer. Acad. Derm., 8: 1-16, 1983.

[11] 11. McGINNIS, M.R.; RINALDI, M.G. & WINN, R.E. Emerging agents of phaeohyphomicosis: pathogenic species of Bipolaris and Exserohilum. J. clin. Microbiol., 24: 250-259, 1986.

[12] 12. McGINNIS, M.R. & HILGER, A.E. Infections caused by black fungi (editorial). Arch. Derm., 123: 1300-1302, 1987.

[13] 13. MORTON, S.J.; MIDTHUN, K. & MERZ, W.G. Granulomatous encephalitis caused by Bipolaris hawaiiensis. Arch. Path. Lab. Med., 110: 1183 1185, 1986.

[14] 14. NELSON, R.R. Cochliobolus intermedius, the perfect stage of Curvularia intermedia. Mycologia, 52: 775 778, 1960.

[15] 15. NELSON, R.R. The perfect stage of Helmonthosporium spiciferum. Mycologia, 56: 196-201, 1964.

[16] 16. PORTO, E.; TAKAHASHI, N.; HEINS, E.M. & LACAZ, C. da S. Nuevo metodo para microcultivo de hongos. Rev. argent. Micol., 4: 24-29, 1981.

[17] 17. RUBEN, S.J.; SCOTT, T.E. & SELTZER, H.M. Intracranial and paranasal sinus infections due to Drechslera. South. med. J., 80: 1057-1058, 1987.

[18] 18. STOCKDALE, P.M. Nannizia incurvata gen. nov., sp. nov., a perfect state of Microsporum gypseum (Bodin) Guiart et Grigorakis. Sabouraudia, 1: 41-48, 1961.

[19] 19. YOUNG, C.N.; SWART, J.G.; ACKERMAN, D. & DIVID-GE-PITTS, K. Nasal obstruction and bone erosion caused by Drechslera hawaiiensis. J. Laryng., 92: 137-143, 1978.

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