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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.34 no.3 São Paulo May/June 1992

http://dx.doi.org/10.1590/S0036-46651992000300004 

ORIGINAL ARTICLES

 

Schistosoma mansoni: host cell adhesion to the different stages of the parasite, in vivo

 

Schistosoma mansoni: adesão de células do hospedeiro aos diferentes estádios do parasito, in vivo

 

 

Alan L. MeloI; Leógenes H. PereiraI; Conceição R. S. MachadoII

IGrupo Interdepartamental de estudos Sobre Esquistossomose/Departamento de Parasitologia - Instituto de Ciências Biológicas da UFMG - Caixa Postal 2486 CEP 30161 Belo Horizonte, Brazil
IIDepartamento de Morfologia - Instituto de Ciências Biológicas da UFMG - Caixa Postal 2486 CEP 30161 Belo Horizonte, Brazil

 

 


SUMMARY

The peritoneal cavity of laboratory mice was used to study the phenomenon of host cell adhesion to different evolutive stages of the Schistosoma mansoni (cercaria, adult worm, developing and mature eggs, miracidium, young and mature daughter sporocysts). Material recovered from the peritoneal cavity 30 and 180 min after the inoculation of each evolutive form was examined with the help of a stereomicroscope. The free swimming larvae (cercaria and miracidium), and the evolutive forms producing such larvae (mature egg and mature daughter sporocyst) elicited the host cell adhesion phenomenon. In all forms but cercariae the adherent cells remained as so till 180 minutes after inoculation.

Key words: Schistosoma mansoni; Cell adhesion; Peritoneal cavity.


RESUMO

A cavidade peritoneal de camundongos foi utilizada para estudos de adesão celular a diferentes estádios evolutivos do Schistosoma mansoni (cercária, verme adulto, ovos imaturos e maduros, miracídio, esporocisto jovem e esporocisto maduro). O material recuperado da cavidade peritoneal 30 e 180 min após o inóculo, foi examinado com auxílio de estereomicroscópio. As formas livres (cercária e miracídio) e as formas evolutivas que produzem tais larvas (ovo maduro e esporocisto maduro) apresentam células do hospedeiro aderidas à superfície. Em todas as formas, exceto cercária, as células permanecem aderidas pelo menos até 180 min após o inóculo.


 

 

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Recebido para publicação em 26/9/1991.
Aceito para publicação em 11/2/1992.
Supported by FAPEMIG, CNPQ, FINEP (Brazil) and Parasitic Diseases Programme - WHO - Switzerland.

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