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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.35 no.1 São Paulo Jan./Feb. 1993 



Interaction between neutrophils and Schistosoma mansoni larvae in vivo. A transmission electron-microscopic study


Interação entre neutrófilos e larvas de Schistosoma mansoni in vivo. Estudo ao microscópio eletrônico de transmissão



Alan Lane de MeloI; Conceição Ribeiro da Silva MachadoII; Leógenes Horácio PereiraI

IDepartamento de Parasitologia e Grupo Interdepartamental de Estudos sobre Esquistossomose (GIDE)
IIDepartamento de Morfologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, 31270-901 - Belo Horizonte, Brasil




Schistosoma mansoni cercariae were inoculated into the peritoneal cavity of naive mice and recovered 30 minutes later. Ultrastructural studies showed that neutrophils adhere to the larval surface and participate in the removal of glycocalyx by phagocytosis. This finding suggests that the neutrophils can play a role on the cercaria-schistosomulum transformation process.

Key words: Neutrophils; Schistosoma mansoni; Cercaria transformation.


Cercárias de Schistosoma mansoni foram inoculadas na cavidade peritoneal de camundongos normais e recuperadas 30 minutos depois. Estudos ultra-estruturais mostraram que neutrófilos aderem à superfície da larva, participando da remoção do glicocálice através de fagocitose. Este achado sugere que neutrófilos possam ter papel no processo de transformação de cercária em esquistossômulo.



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Recebido para publicação em 24/6/1992
Aceito para publicação em 24/08/1992.
Financial support has been provided by the Parasitic Diseases Programme, World Health Organization, Switzerland, and FINEP/CNPq, Brazil.

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