The frequency of blood-born viral infections in a population of multitransfused Brazilian patients

Freqüência de infecções virais transmitidas por transfusões em uma população de pacientes brasileiros multitransfundidos

EPIDEMIOLOGY

The frequency of blood-born viral infections in a population of multitransfused Brazilian patients

Freqüência de infecções virais transmitidas por transfusões em uma população de pacientes brasileiros multitransfundidos

Dimas T. Covas; Edmir Boturão Neto; Marco A. Zago

Regional Blood Center and Division of Hematology, School of Medicine of Ribeirão Preto

^{Address for correspondence}

SUMMARY

The frequency of viral markers for hepatitis B (HBV) and C (HCV), human immunodeficiency virus-1 (HIV-1) and human T-lymphotropic virus-1 (HTLV-1) was evaluated in 32 Brazilian ß-thalassemia multitransfused patients. Additionaly the serum concentrations of ferritin and alanine aspartate transaminase (ALAT) were determined. The results show a high prevalence of markers of infection by HBV (25.0%) and HCV (46.8%) and a low prevalence of markers for HIV-1 and HTLV-1. No correlations were demonstrated between the presence of the hepatitis markers and the number of units transfused or the serum concentrations of ferritin and ALAT.

Key words: Blood-Born Viral Infections; ß-thalassemia; Hepatitis; HIV-1; HTLV-1.

RESUMO

A freqüência de marcadores virais para hepatite B (HBV), C (HCV), vírus da imunodeficiência humana-1 (HIV-1) e vírus linfotrópico-T humano (HTLV-1) foi avaliada em 32 pacientes brasileiros multitransfundidos, portadores de ß-talassemia. Adicionalmente determinou-se a concentração sérica de transaminase alani-na aspártica (ALAT) e de ferritina. Os resultados mostraram alta prevalência de marcadores para HBV (25,0%) e HCV (46,8%) e baixa prevalência de marcadores para HIV-1 e HTLV-1. Não se demonstrou correlação entre a presença de marcadores para hepatite e o número de unidades transfundidas ou com as concentrações séricas de ferritina e ALAT.

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Recebido para publicação em 01/09/1992

Aceito para publicação em 03/12/1992

Supported by grants from the Fundação Hemocentro de Ribeirão Preto (FUNDHERP), Brazil.

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Address for correspondence:

Dr. Dimas Tadeu Covas

Hemocentro de Ribeirão Preto

14048-900 Ribeirão Preto, Brazil

FAX nº 55 16 633-11.44

Publication Dates

• Publication in this collection
  20 July 2006
• Date of issue
  June 1993

History

• Received
  01 Sept 1992
• Accepted
  03 Dec 1992