Resumos
São descritos os dois primeiros casos de neurocriptococose durante a gravidez diagnosticados em São Paulo (Brasil). Uma paciente foi tratada com anfotericina B no segundo trimestre, a outra, com anfotericina B no primeiro trimestre e no 2º trimestre com anfotericina B e 5 flucitosina. Ambas tiveram boa evolução materna e fetal. É apresentada revisão da literatura da neurocriptococose em gestantes.
Neurocriptococose; Gravidez; Anfotericina B; Flucitosina
Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage. The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed. A review of the literature concerning neurocryptococcosis during pregnancy is presented.
REGISTRO DE CASO
Neurocriptococose durante a gravidez. Revisão da literatura. Relato de dois casos
Cryptococcal meningitis in pregnancy. Review of the literature. Report of two cases
Carlos Alberto Pires PereiraI; Olga FischmanII; Arnaldo Lopes ColomboI; Antonio Fernandes MoronIII; Antonio Carlos Campos PignatariI
IDisciplina de Doenças Infecciosas e Parasitárias da Escola Paulista de Medicina. São Paulo, SP, Brasil
IIDisciplina de Biologia Celular, Setor de 'Micologia Médica da Escola Paulista de Medicina. São Paulo, SP, Brasil
IIIDisciplina de Obstetrícia da Escola Paulista de Medicina. São Paulo, SP, Brasil
Endereço para correspondência Endereço para correspondência: Carlos Alberto Pires Pereira Rua Napoleão de Barros, 715 - 1º andar Vila Clementino. CEP 04023-062 São Paulo, SP, Brasil Fone: 572-6348, Fax: (011) 572-6348 ou 549-2127
RESUMO
São descritos os dois primeiros casos de neurocriptococose durante a gravidez diagnosticados em São Paulo (Brasil). Uma paciente foi tratada com anfotericina B no segundo trimestre, a outra, com anfotericina B no primeiro trimestre e no 2º trimestre com anfotericina B e 5 flucitosina. Ambas tiveram boa evolução materna e fetal.
É apresentada revisão da literatura da neurocriptococose em gestantes.
Unitermos: Neurocriptococose; Gravidez; Anfotericina B; Flucitosina.
SUMMARY
Two cases of neurocryptococcosis were diagnosed during pregnancy in São Paulo (Brazil). Amphotericin B was used in the second trimester in one patient. The other, received amphotericin B during the first trimester of pregnancy and 5-fluorocytosine was added in the second trimester. In both, the pregnancy was uneventful and the fetus suffered no damage.
The therapy used to treat pregnant women with cryptococcal meningitis is commented. The newborn follow-up is discussed.
A review of the literature concerning neurocryptococcosis during pregnancy is presented.
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Recebido para publicação em 20/10/1992
Aceito para publicação em 21/12/1992
Trabalho realizado na Escola Paulista de Medicina - Hospital São Paulo. Rua Botucatú, 740 - Vila Clementino. São Paulo, SP, Brasil.
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Datas de Publicação
-
Publicação nesta coleção
21 Jul 2006 -
Data do Fascículo
Ago 1993
Histórico
-
Aceito
21 Dez 1992 -
Recebido
20 Out 1992