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Revista do Instituto de Medicina Tropical de São Paulo

versão On-line ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo v.36 n.6 São Paulo nov./dez. 1994

http://dx.doi.org/10.1590/S0036-46651994000600003 

MICROBIOLOGY

 

Bacterial agents isolated from cerebrospinal fluid of patients with Acquired Immunodeficiency Syndrome (AIDS) and neurological complications

 

Agentes bacterianos isolados de líquido cefalorraquidiano de pacientes com Síndrome de Imunodeficiência Adquirida (SIDA) e complicações neurológicas

 

 

Ilka Maria LandgrafI; Moisés PalaciI; Maria de Fátima Paiva VieiraI; Sueli Yoko Mizuka UekiI; Maria Conceição MartinsI; Daisy Nakamura SatoI; Lucilaine FerrazoliI; Maria Alice Silva TellesI; Maria Cecília Outeiro GorlaI; Tania Mara Ibelli VazI; Rosemarie LorençoII; Lilian Regina Macelloni MarquesI

ISeção de Bacteriologia, Instituto Adolfo Lutz, Av. Dr. Arnaldo 355, 01246-902 São Paulo, SP, Brasil
IIInstituto de Infectologia Emílio Ribas, Av. Dr. Arnaldo, 165, 01245-901 São Paulo, SP, Brasil

Correspondence to

 

 


SUMMARY

Cerebrospinal fluid (CSF) samples from 2083 patients with acquired immunodeficiency syndrome (AIDS) and neurological complications were bacteriologically examined during a period of 7 years (1984-1990). The percentage of patients who had at least one bacterial agent cultured from the CSF was 6.2%. Mycobacterium tuberculosis was the most frequently isolated agent (4.3%), followed by Mycobacterium avium complex or MAC (0.7%), Pseudomonas spp (0.5%), Enterobacter spp (0.4%), and Staphylococcus aureus (0.3%). Among 130 culture positive patients, 89 (68.5%) had M. tuberculosis and 15 (11.6%) had MAC. The frequency of bacterial isolations increased from 1988 (5.2%) to 1990 (7.2%), partly due to the increase in MAC isolations. Bacterial agents were more frequently isolated from patients in the age group 21-30 years and from women (p<0.05).

Keywords: Acquired Immunodeficiency Syndrome; Cerebrospinal fluid; Bacterial agents.


RESUMO

Amostras de líquido cefalorraquidiano (LCR) de 2083 pacientes com Síndrome de Imunodeficiência Adquirida (SIDA) e complicações neurológicas foram examinados durante um período de 7 anos (1984-1990). A porcentagem de pacientes que tiveram pelo menos um agente bacteriano cultivado do LCR foi de 6,2%. Mycobacterium tuberculosis foi o mais frequentemente isolado (4,3%), seguido do complexo Mycobacterium avium ou MAC (0,7%), de Pseudomonas spp (0,5%), Enterobacter spp (0,4%), e Staphylococcus aureus (0,3%). Entre 130 pacientes com cultura positiva, de 89 (68,5%) foi isolado M. tuberculosis e de 15 (11,6%) MAC. A frequência de isolamentos bacterianos aumentou de 1988 (5,2%) a 1990 (7,2%), particularmente devido ao maior isolamento de MAC. Os agentes bacterianos foram mais frequentemente isolados de pacientes na faixa etária de 21-30 anos e de mulheres (p<0.05).


 

 

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

 

 

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Correspondence to:
Ilka Maria Landgraf
Seção de Bacteriologia, Instituto Adolfo Lutz
Av. Dr. Arnaldo 355
01246-902 São Paulo, SP, Brasil
Fax: 055-011-851-3505

Recebido para publicação em 18/04/1994.
Aceito para publicação em 17/06/1994.

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