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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.37 no.2 São Paulo Mar./Apr. 1995

http://dx.doi.org/10.1590/S0036-46651995000200001 

MICROBIOLOGY

 

Mycobacterium avium complex (MAC): an unusual potential pathogen in cerebrospinal fluid of AIDS patients

 

Complexo Mycobacterium avium: um patógeno potencial pouco comum no líquido céfalo -raquidiano de pacientes com AIDS

 

 

David Jamil HadadI; Tereza Cristina PetryII; Anaenza Freie MarescaIII; Lucilaine FerrazoliIV; Maria Conceição MartinsIV; Maria Cecilia de Almeida PalharesV; Walkyria Pereira PintoVI; Adauto Castelo FilhoVII; Moises PalaciIV

IMédico infectologista do Centro de Referência e Treinamento AIDS (CRTA), Mestre em Doenças Infecciosas e Parasitárias pela Escola Paulista de Medicina
IIMédico Infectologista do CRTA
IIIEx-Infectologista do CRTA
IVPesquisadores Científicos do Setor de Micobactérias do Instituto Adolfo Lutz
VChefe do Laboratório do CRTA
VIDiretora Técnica do CRTA
VIIProfessor Adjunto da Disciplina de Doenças Infecciosas e Parasitárias da Escola Paulista de Medicina

Correspondence to

 

 


SUMMARY

Mycobacterium avium complex (MAC) is frequently isolated from patients with late complications of Acquired Immunodeficiency Syndrome (AIDS), especially in North America and Europe. However, its isolation from the central nervous system (CNS) has been seldom reported in these countries. MAC infections in AIDS patients in African and Latin American countries are believed to be uncommon. We report the isolation of MAC from cerebrospinal fluid (CSF) of 11 AIDS patients out of 1723 (0.63%) seen at "Centro de Referência e Treinamento - AIDS", São Paulo and discuss the significance of its isolation.

Keywords: Mycobacterium avium complex (MAC); Cerebrospinal fluid (CSF); Acquired immunodeficiency syndrome (AIDS).


RESUMO

O complexo Mycobacterium avium (CMA) é frequentemente isolado de pacientes com complicações tardias de Síndrome de Imunodeficiência Adquirida (AIDS), especialmente na América do Norte e Europa. Entretanto, existem poucos relatos do isolamento deste complexo a partir do sistema nervoso central (SNC) nestes países. Acredita-se que infecções pelo CMA sejam raras entre pacientes portadores de AIDS em países da África e América Latina. Neste trabalho relatamos o isolamento do CMA do líquor de 11 pacientes portadores de AIDS dentre 1723 (0.63%) atendidos no Centro de Referência e Treinamento -AIDS, de São Paulo, e discutimos a significância deste achado.


 

 

Full text available only in PDF format.

Texto completo disponível apenas em PDF.

 


ACKNOWLEDGEMENTS

We are grateful to Prof. Dr. Gildo Del Negro, from Faculdade de Medicina - Universidade de São Paulo, for his critical review of this manuscript.

 

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Correspondence to:
David Jamil Hadad
Rua Dr. Diogo de Faria, 666/35
Vila Clementino, 04037-222 São Paulo, S.P., Brasil

Recebido para publicação em 05/09/1994
Aceito para publicação em 20/09/1994

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