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Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.38 no.3 São Paulo May/June 1996 



Progression of Salmonella Enteritidis phage type 4 strains in São Paulo State, Brazil


Disseminação de cepas de Salmonella Enteritidis do fagotipo 4 (PT-4) em São Paulo, Brasil



K. Irino; S.A. Fernandes; A.T. Tavechio; B.C. Neves; A.M.G. Dias

Correspondence to




A total of 574 S. Enteritidis strains (383 from human sources and 191 from non-human sources) isolated between 1975-95, in São Paulo State, Brazil, were phagetyped. Among the strains isolated during the period of 1975-92, 80.9% of them belonged to phage type 8 (PT-8), but in 1993 strains of PT-4 accounted for 65.2% of all the S. Enteritidis isolates. In the following years, PT-4 strains accounted for 99.7% and 98.4% of phagetyped S. Enteritidis strains. The results obtained suggested that the current epidemic of S. Enteritidis in São Paulo State is clearly associated with the progression of PT-4 strains.

Keywords: Salmonella; S. Enteritidis; Phage types.


Um total de 574 cepas de Salmonella Enteritidis isoladas no período 1975-95, em São Paulo, Brasil, foram fagotipadas. Entre estas cepas, 383 eram de origem humana e 191 isoladas de materiais de origem não humana. Verificou-se que a grande maioria (80.9%) das cepas isoladas até 1992 pertencia ao fagotipo 8 (PT-8) e que cepas do fagotipo 4 (PT-4) começaram a predominar a partir de 1993. Cepas deste fagotipo corresponderam em 1993, 1994 e 1995, respectivamente, a 65.2%, 99.7% e 98.4% das amostras fagotipadas. O aumento da S. Enteritidis em São Paulo está claramente associado a disseminação de cepas PT-4.



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We are very grateful to Dr. B. Rowe from the Division of Enteric Pathogens, Central Public Health Laboratories, Colindale, London, UK, for providing S. Enteritidis phages and type strains. We would like to thank our collegues from Regional Laboratories who provided S. Enteritidis strains.



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Correspondence to:
Kinue Irino
Instituto Adolfo Lutz Seção de Bacteriologia
Av. Dr. Arnaldo, 355
01246-902 São Paulo, Brazil
Tel.: 011-3061-0111 ramal 213. Fax: 011-853-3505

Recebido para publicação em 06/05/1996
Aceito para publicação em 02/07/1996

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