SciELO - Scientific Electronic Library Online

vol.38 issue3Progression of Salmonella Enteritidis phage type 4 strains in São Paulo State, BrazilFour adult hemoglobin types in one mulatto family author indexsubject indexarticles search
Home Pagealphabetic serial listing  

Services on Demand




Related links


Revista do Instituto de Medicina Tropical de São Paulo

On-line version ISSN 1678-9946

Rev. Inst. Med. trop. S. Paulo vol.38 no.3 São Paulo May/June 1996 



Gastrointestinal translocation as a possible source of candidemia in an AIDS patient


Translocação gastrointestinal como possível fonte de fungemia em paciente portador de AIDS



Arnaldo Lopes ColomboI; Maria Luiza BranchiniIII; Débora GeigerII; Ana Lucia SchimidtI; Antonio Carlos Campos PignatariI; Olga FischmanII

IDivision of Infectious Diseases from Escola Paulista de Medicina - Universidade Federal de São Paulo, São Paulo, SP, Brazil
IIDivision of Celular Biology from Escola Paulista de Medicina - Universidade Federal de São Paulo, São Paulo, SP, Brazil
IIIDivision of Infectious Diseases from Faculdade de Ciências Médicas - Universidade de Campinas, Campinas, SP, Brazil

Correspondence to




Apart from cryptococcosis and histoplasmosis, which are mycoses contained by T cell-mediated mechanisms of host defense, fungemia is rarely found in AIDS patients. The frequency of fungemia due to Candida spp. has been reported to be as low as 1 %. We report a non-neutropenic AIDS patient who presented a candidemia which probably arose from her gastrointestinal tract.

Keywords: Fungemia; AIDS; Candidiasis.


Diferente de histoplasmose e criptococose, doenças fúngicas associadas a depressão da imunidade celular, fungemia causada por Candida spp. tem sido raramente relatada em pacientes com AIDS. O presente relato ilustra um caso de candidemia em paciente não neutropênico portador de AIDS, cuja origem parece ter sido via translocação através do trato gastrointestinal.



Full text available only in PDF format.

Texto completo disponível apenas em PDF.




1. BARCHIESI, F.; MORBIDUCCI, V.; ANCARANI, F. & SCALISE, A.D. - Trichosporon beigelii fungemia in AIDS patient. AIDS, 7: 139-140, 1993.         [ Links ]

2. BRANCHINI, M.L.; PFALLER, M.A.; RHINE-CHALBERG, J.; FREMPONG, T. & ISEMBERG, H.D. - Genotipic variation and slime production among blood and catheter isolates of Candida parapsilosis. J. clin. Microbiol., 32: 452-456, 1994.         [ Links ]

3. DIAMOND, R.D. - The growing problem of mycoses in patients infected with the Human Immunodeficiency Virus. Rev. infect. Dis., 13: 480-486, 1991.         [ Links ]

4. DUPONT, B.; GRAYBILL, J.R.; ARMSTRONG, D. et al. - Fungal infections in AIDS patients. J. Med. vet. Mycol., 30 (suppl. 1): 19-28, 1992.         [ Links ]

5. GUBBINS, P.O.; PISCITELLI, S.C. & DANZIGER, L.H. - Candidal urinary tract infections: a comprehensive review of their diagnosis and management. Pharmacotherapy, 13: 110-127, 1993.         [ Links ]

6. KRAUSE, W.; MATHEIS, H. & WULF, K. - Fungemia and funguria after oral administration of C. albicans. Lancet, 1: 598-599, 1969.         [ Links ]

7. LAGUNA, F. & RODRIGUEZ-TUDELA, E. - Fungemia due to fluconazole-resistant Candida albicans in a patient with AIDS. Clin. infect. Dis., 19: 542-543, 1994.         [ Links ]

8. LEHRER, R.I. – Inhibition by sulfonamides of the candidacidal activity of human neutrophils. J. clin. Invest., 50: 2498-2505, 1971.         [ Links ]

9. WADE, J.C. – Epidemiology of Candida infections. In: BODEY, G.P., ed. Candidiasis: pathogenesis, diagnosis, and treatment. 2. ed. New York, Raven Press, 1993. p. 85.         [ Links ]

10. WALSH, T.J.; BUSTAMANTE, C.I.; VLAHOV, D. & STANDIFORD, H.C. - Candidal suppurative peripheral thrombophlebitis: recognition, prevention and management. Infect. Control, 7: 16-22, 1986.         [ Links ]

11. WHIMBEY, E.; GOLD, J.W.; POLSKY, B. et al. – Bacteremia and fungemia in patients with the acquired immunodeficiency syndrome. Ann. intern. Med., 104: 511-514, 1986.         [ Links ]

12. WILKES, M.S.; FORTIN, A.H.; FELIX, J.C; GODWIN, T.A. & TOMPSON, W.G. – Value of necropsy in acquired immunodeficiency syndrome. Lancet, 2: 85-88, 1988.         [ Links ]



Correspondence to:
Arnaldo Lopes Colombo, MD
Division of Infectious Diseases/Escola Paulista de Medicina - UNIFESP
Rua Botucatu 740
04023-062 São Paulo, SP, Brazil
FAX: (5511) 549-2127, PHONE: (5511)572-6348

Recebido para publicação em 13/09/1995.
Aceito para publicação em 27/06/1996.

Creative Commons License All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License