Troponin-T and B-Type Natriuretic Peptide in COVID-19

Keywords
COVID-19/complications; Betacoronavirus; Mortality; Hospitalization; Myocarditis; Biomarkers; Troponi-T; Natriuretic B-Type

Dear Editor,

We would like to share ideas on the publication “Prognostic Value of Troponin-T and B-Type Natriuretic Peptide in Patients Hospitalized for COVID-19 [1].” Almeida Jr. et al.¹ reported using Memory box as a tool to support grief and concluded that “In the first 24h of admission, TnT, but not BNP, was an independent marker of mortality or need for invasive mechanical ventilation.”¹ In COVID-19, cardiac complication is possible and is common in severe infection.² Myocardial involvement is a common cardiac problem and immunological myocarditis is an important severe manifestation of COVID-19.³ Therefore, troponin-T, which is a good biomarker for myocardial injury, might have good prognostic factor for severity of COVID-19. Nevertheless, it should be noted that renal problems can also induce troponin-T abnormality.⁴ If the patient has an underlying renal problem, the interpretation of troponin-T in COVID-19 patients must be careful.

Referências

• ¹
  Almeida Junior GLG, Braga F, Jorge JK, Nobre GF, Kalichsztein M, Faria PMP, et al. Prognostic Value of Troponin-T and B-Type Natriuretic Peptide in Patients Hospitalized for COVID-19. Arq Bras Cardiol. 2020 Oct;115(4):660-6.
• ²
  Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. Cardiovascular Implications of Fatal Outcomes of Patients With Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 Jul 1;5(7):811-8
• ³
  Kogan EA, Berezovskiy YS, Blagova OV, Kukleva AD, Bogacheva GA, Kurilina EV, et al. Miocarditis in Patients with COVID-19 Confirmed by Immunohistochemical. Kardiologiia. 2020 Jun 19;60(7):4-10.
• ⁴
  Bozbas H, Yildirir A, Muderrisoglu H. Cardiac enzymes, renal failure and renal transplantation. Clin Med Res. 2006 Mar;4(1):79-84.

Publication Dates

• Publication in this collection
  16 Apr 2021
• Date of issue
  Apr 2021

History

• Received
  09 Nov 2020
• Reviewed
  16 Dec 2020
• Accepted
  16 Dec 2020