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Memórias do Instituto Oswaldo Cruz

Print version ISSN 0074-0276On-line version ISSN 1678-8060

Mem. Inst. Oswaldo Cruz vol.46 no.4 Rio de Janeiro Dec. 1948

http://dx.doi.org/10.1590/S0074-02761948000400008 

Estudos sobre a regeneração do figado - variação do volume nuclear das celulas hepáticas em repouso divisional

Fernando Ubatuba

Jorge Costa de Morais

ABSTRACT

Surgical removal of large amounts of hepatic tissue in male albino rats results in a rapid and conspicuous raise in cellular nuclear volumes. Measurements were made exclusively in resting nuclei. This volume variation is transitory. Nuclear volumes return to the normal value withins 6 days of restoration. The higher value are abserved 48 hours after the hepatic removal, indicating probably that this effect is due to hydration of the nucei, as occurs in the cytoplasm. This hydration could be correlated to the mitotic activity of the renmant tissue since a peak of mitoses parallels the changes in the nuclear volumes.

 

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