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Thymulin: biochemistry, biology and therapeutical applications

Abstract

Thymulin is a pharmacologically active metallononapeptide inducing the differentiation of T cells and enhancing several functions of the various T cell subsets in normal or partially thymus-deficient recipients. Its effect on suppressor T cells is, so far, the most remarkable and should be the first to find useful clinical applications. The peptide is a natural hormone, available in synthetic form. It is not toxic and one may foresee its clinical use as one of the major immunoregulatory agents in the near future.


ABSTRACT

Thymulin: biochemistry, biology and therapeutical applications

Mireille Dardenne1

J. F. Bach1

INSERM U 25, Hôpital Necker, Paris, France

Thymulin is a pharmacologically active metallononapeptide inducing the differentiation of T cells and enhancing several functions of the various T cell subsets in normal or partially thymus-deficient recipients. Its effect on suppressor T cells is, so far, the most remarkable and should be the first to find useful clinical applications. The peptide is a natural hormone, available in synthetic form. It is not toxic and one may foresee its clinical use as one of the major immunoregulatory agents in the near future.

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Publication Dates

  • Publication in this collection
    26 June 2009
  • Date of issue
    1987
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