Abstract
The recent findings on immunodiagnosis of schistosomiasis mansoni have shown that purified Schistosoma mansoni antigens do not provide maximum positivity. Therefore, the authors suggest the use of semi-purified antigens for diagnostic purposes. So far, no serological marker for cured patients as shown by negative stool examination was found. However, a tendency of IgG antibody titre decrease was observed, when egg antigen was used.
Schistosomiasis mansoni: immunodiagnosis aspects and search for an immunological marker related to therapeutic efficacy
Hermínia Y. Kanamura1
Sumie Hoshino-Shimizu1
Dirce M. C. Lima2
Clarice P. Abrantes2
Luiz Caetano da Silva2
Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, São Paulo, Brasil
Instituto de Medicina Tropical de São Paulo, São Paulo, Brasil
The recent findings on immunodiagnosis of schistosomiasis mansoni have shown that purified Schistosoma mansoni antigens do not provide maximum positivity. Therefore, the authors suggest the use of semi-purified antigens for diagnostic purposes. So far, no serological marker for cured patients as shown by negative stool examination was found. However, a tendency of IgG antibody titre decrease was observed, when egg antigen was used.
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Publication Dates
-
Publication in this collection
26 June 2009 -
Date of issue
1987
